Results 101 to 110 of about 1,109,000 (367)

Clinical implications of carcinoembryonic antigen distribution in serum exosomal fraction—Measurement by ELISA

PLoS ONE, 2017
Background Serum exosomal proteins have great potential as indicators of disease status in cancer, inflammatory or metabolic diseases. The association of a fraction of various serum proteins such as carcinoembryonic antigen (CEA) with circulating ...
S. Yokoyama, Akihiro Takeuchi, Shunsuke Yamaguchi, Y. Mitani, Takashi Watanabe, K. Matsuda, T. Hotta, J. Shively, H. Yamaue   +8 more
semanticscholar   +1 more source

Impact of Body Weight Loss During Preoperative Chemoradiotherapy on Prognosis of Patients With Lower Rectal Cancer

Annals of Gastroenterological Surgery, EarlyView.
The present study aimed to investigate the relationship between changes in body weight and composition during chemoradiotherapy, such as the psoas muscle mass index, visceral fat index, and subcutaneous fat index obtained from computed tomography images, and long‐term outcomes in rectal cancer patients.
Shinya Abe, Hiroaki Nozawa, Kazuhito Sasaki, Koji Murono, Shigenobu Emoto, Yuichiro Yokoyama, Yuzo Nagai, Yuzo Harada, Takahide Shinagawa, Soichiro Ishihara   +9 more
wiley   +1 more source

Short‐ and Long‐Term Outcomes of Subtotal Gastrectomy for Remnant Gastric Cancer: A Multicenter Study

Annals of Gastroenterological Surgery, EarlyView.
This multicenter study compared subtotal versus completion gastrectomy for remnant gastric cancer. Subtotal gastrectomy was associated with shorter operative time and significantly less postoperative weight loss, with no difference in long‐term survival, suggesting it as a feasible surgical option without compromising oncologic outcomes.
Kensuke Kudou, Mitsuhiko Ota, Kippei Ogaki, Yasue Kimura, Yuta Kasagi, Naomichi Koga, Hirofumi Hasuda, Tetsuro Kawazoe, Eiji Oki, Tomoharu Yoshizumi   +9 more
wiley   +1 more source

CA19-9 as a Potential Target for Radiolabeled Antibody-Based Positron Emission Tomography of Pancreas Cancer. [PDF]

, 2011
Introduction. Sensitive and specific imaging of pancreas cancer are necessary for accurate diagnosis, staging, and treatment. The vast majority of pancreas cancers express the carbohydrate tumor antigen CA19-9. The goal of this study was to determine the
Girgis, Mark D, Kenanova, Vania, McCabe, Katelyn E, Olafsen, Tove, Tomlinson, James S, Wu, Anna M   +5 more
core   +4 more sources

Predicting Postresection Colorectal Liver Metastases Recurrence Using Advanced Graph Neural Networks with Explainability and Causal Inference

Advanced Intelligent Systems, EarlyView.
This study introduces a framework that combines graph neural networks with causal inference to forecast recurrence and uncover the clinical and pathological factors driving it. It further provides interpretability, validates risk factors via counterfactual and interventional analyses, and offers evidence‐based insights for treatment planning ...
Jubair Ahmed, Md. Abdur Rahman, Mohaimenul Azam Khan Raiaan, Sami Azam   +3 more
wiley   +1 more source

The Vietnamese swine as a translational model of invasive ductal carcinoma of the breast

Animal Models and Experimental Medicine, EarlyView.
The flow diagram outlines the chemical induction of breast tumors through a single intraperitoneal dose of MNU. Tumor development was assessed using ultrasound and clinical examination. After 14 weeks, mammary tissue was collected and histologically analyzed to evaluate structural similarities between sows and humans, the carcinogenic potential of MNU,
Claudia Elizabeth Vera‐Tizatl, Arturo Vera‐Hernández, Lorenzo Leija‐Salas, Marco Antonio Vega‐López, María del Carmen Ramírez‐Estudillo, German Isauro Garrido Fariña, Adriana Leticia Vera‐Tizatl   +6 more
wiley   +1 more source

Mice Transgenic for the Human Carcinoembryonic Antigen Gene Maintain Its Spatiotemporal Expression Pattern [PDF]

, 1994
The tumor marker carcinoembryonic antigen (CEA) is predominantly expressed in epithelial cells along the gastrointestinal tract and in a variety of adenocarcinomas.
Eades-Perner, Anne-Marie, Hirth, Antje, Kleist, Sabine von, Neumaier, Michael, Putten, Herman van der, Thompson, John A., Zimmermann, Wolfgang   +6 more
core  

Impact of extended insurance coverage on survival outcomes among patients with metastatic colorectal cancer in Taiwan

British Journal of Clinical Pharmacology, EarlyView.
Aims Predetermined treatment duration limits (PTDLs) are often used by Taiwan's National Health Insurance Administration to contain healthcare costs, but they may compromise patient outcomes. Therefore, we studied Taiwan's 2017 extension of the bevacizumab PTDL from 24 to 36 weeks in metastatic colorectal cancer (mCRC) to evaluate whether prolonged ...
Wei‐Ming Huang, Chen‐Han Chueh, Chien‐Yu Tseng, Christopher N. Kaufmann, Earl J. Morris, Chiao‐En Wu, Yi‐Wen Tsai   +6 more
wiley   +1 more source

Neural precursor cells derived from induced pluripotent stem cells exhibit reduced susceptibility to infection with a neurotropic coronavirus. [PDF]

, 2017
The present study examines the susceptibility of mouse induced pluripotent stem cell-derived neural precursor cells (iPSC-NPCs) to infection with the neurotropic JHM strain of mouse hepatitis virus (JHMV).
Lane, Thomas E, Mangale, Vrushali, Marro, Brett S, Plaisted, Warren C, Walsh, Craig M   +4 more
core   +1 more source

Lymph node metastasis risk factors in T2 colorectal cancer

DEN Open
Objectives This study evaluates risk factors for lymph node metastasis (LNM) in T2 colorectal cancer to refine patient selection for endoscopic resection. Methods We reviewed records from consecutive patients who had undergone curative surgical resection
Yuriko Morita, Shin‐ei Kudo, Yuki Takashina, Katsuro Ichimasa, Yuta Kouyama, Shigenori Semba, Kenichi Mochizuki, Osamu Shiina, Shun Kato, Takanori Kuroki, Shoji Shimada, Kenta Nakahara, Yusuke Takehara, Shunpei Mukai, Noriyuki Ogata, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Naruhiko Sawada, Tetsuo Nemoto, Toshiyuki Baba, Masashi Misawa   +21 more
doaj   +1 more source