Results 111 to 120 of about 84,483 (336)

A computational study of the statistical mechanics of antibody-antigen conformations [PDF]

arXiv, 2004
We describe the representation of the chemical affinity between the antigen-combining site of the immunoglobulin molecule and the antigen molecule as the probability of the two molecules existing in a bound state. Our model is based on the identification of shape attractors in the configuration space for the joint antibody / antigen combining site ...
arxiv  

Occult mucin-producing urothelial-type adenocarcinoma of the prostate with elevated serum levels of carcinoembryonic antigen and carbohydrate antigen 19-9: Report of an autopsy-proven case

Urology Case Reports, 2019
Mucin-producing urothelial-type adenocarcinoma of the prostate (MPUAP) is a rare, aggressive neoplasm thought to originate from the prostatic urethral urothelium.
Keisuke Nonaka, Yoko Matsuda, Mototsune Kakizaki, Shoichiro Takakuma, Tomoyasu Matsubara, Shigeo Murayama, Toshiyuki Ishiwata, Masashi Kameyama, Kazuto Ogura, Sumiko Kobayashi, Tomio Arai   +10 more
doaj  

Lymph node metastasis risk factors in T2 colorectal cancer

DEN Open
Objectives This study evaluates risk factors for lymph node metastasis (LNM) in T2 colorectal cancer to refine patient selection for endoscopic resection. Methods We reviewed records from consecutive patients who had undergone curative surgical resection
Yuriko Morita, Shin‐ei Kudo, Yuki Takashina, Katsuro Ichimasa, Yuta Kouyama, Shigenori Semba, Kenichi Mochizuki, Osamu Shiina, Shun Kato, Takanori Kuroki, Shoji Shimada, Kenta Nakahara, Yusuke Takehara, Shunpei Mukai, Noriyuki Ogata, Takemasa Hayashi, Kunihiko Wakamura, Hideyuki Miyachi, Naruhiko Sawada, Tetsuo Nemoto, Toshiyuki Baba, Masashi Misawa   +21 more
doaj   +1 more source

cDNA Cloning Demonstrates the Expression of Pregnancy-Specific Glycoprotein Genes, a Subgroup of the Carcinoembryonic Antigen Gene Family, in Fetal Liver [PDF]

, 1989
The pregnancy-specific glycoprotein (PSG) genes constitute a subgroup of the carcinoembryonic antigen (CEA) gene family. Here we report the cloning of four cDNAs coding for different members of the PSG family from a human fetal liver cDNA library.
Thompson, John A., Weiss, Martina, Zimmermann, Wolfgang   +2 more
core   +1 more source

A severity‐based tumor‐superior mesenteric/portal vein interface grading criteria as a predictor of survival outcomes in pancreatic head ductal adenocarcinoma patients undergoing pancreaticoduodenectomy following neoadjuvant chemoradiotherapy

Annals of Gastroenterological Surgery, EarlyView.
PDAC patients with the radiological severe interface (≥25 contact length and ≥210 degrees circumferential tumor‐SMV/PV interface) may help predict poor survival outcomes preoperatively. Abstract Aim To assess the ability of a new severity‐based tumor‐superior mesenteric/portal vein interface criteria to predict survival outcomes in pancreatic ductal ...
Benson Kaluba, Naohisa Kuriyama, Motonori Nagata, Takahiro Ito, Aoi Hayasaki, Takehiro Fujii, Yasuhiro Murata, Akihiro Tanemura, Masashi Kishiwada, Shugo Mizuno   +9 more
wiley   +1 more source

A General Theory for Direct Quantitative Analysis of Antigen [PDF]

arXiv, 2011
A theory for direct quantitative analysis of an antigen is proposed. It is based on a potential homogenous immunoreaction system. It establishes an equation to describe the concentration change of the antigen and antibody complex. A maximum point is found in the concentration profile of the complex which can be used to calculate the concentration of ...
arxiv  

Medullary Thyroid Cancer Discovered Through Elevated Carcinoembryonic Antigen Levels Post Colorectal Cancer Resection

Annals of Internal Medicine: Clinical Cases
Medullary thyroid carcinoma (MTC) is a rare malignancy accounting for approximately 5% of all thyroid cancers. Common predictors of aggressiveness of MTC include specific RET mutations and levels of calcitonin.
Andrew Glaza, Jeffrey Margolis
doaj   +1 more source

Triple peptide vaccination as consolidation treatment in women affected by ovarian and breast cancer: clinical and immunological data of a phase I/II clinical trial [PDF]

, 2016
Vaccination with priming and expansion of tumour reacting T cells is an important therapeutic option to be used in combination with novel checkpoint inhibitors to increase the specificity of the T cell infiltrate and the efficacy of the treatment. In
Antonilli M, BARCHIESI, GIACOMO, BELLATI, FILIPPO, BENEDETTI PANICI, PIERLUIGI, CAPONNETTO, SALVATORE, Iadarola R, NAPOLETANO, Chiara, NUTI, Marianna, PIERELLI, LUCA, RAHIMI KOSHKAKI, HASSAN, RUGHETTI, Aurelia, RUSCITO, ILARY, VISCONTI, Valeria, ZIZZARI, ILARIA GRAZIA   +13 more
core   +1 more source

Does surgical intervention contribute to survival for patients with para‐aortic lymph node metastasis from colorectal cancer?

Annals of Gastroenterological Surgery, EarlyView.
Overall survival of patients who underwent surgical resection was significantly better compared to that of patients who underwent chemotherapy without surgical resection. These results highlight the benefit of surgical intervention to survival for patients with isolated para‐aortic lymph node metastasis or with resectable liver metastasis.
Akira Ouchi, Koji Komori, Sono Ito, Yusuke Kinugasa, Soichiro Ishihara, Akio Shiomi, Yukihide Kanemitsu, Takeshi Suto, Hiroki Takahashi, Yoichi Ajioka, on behalf of the study group for PALNM projected by JSCCR, Akinobu Furutani, Akira Hirata, Atsushi Ishibe, Eiji Sunami, Heita Ozawa, Hideki Ueno, Hideyuki Ishida, Hiroyuki Egi, Ichiro Takemasa, Jun Watanabe, Junichiro Hiro, Kay Uehara, Kazushige Kawai, Koya Hida, Manabu Shiozawa, Masaaki Ito, Masakatsu Numata, Masanori Hotchi, Masaya Hiyoshi, Masayuki Ohue, Michio Itabashi, Ryo Inada, Shuntaro Nagai, Takaya Kobatake, Takeshi Kato, Tomohiro Yamaguchi, Yasumasa Takii, Yasumitsu Hirano, Yoshihiro Kakeji   +39 more
wiley   +1 more source

Significance of Intraoperative Lavage Cytology in Perihilar Cholangiocarcinoma

Annals of Gastroenterological Surgery, EarlyView.
ABSTRACT Background Perihilar cholangiocarcinoma (PHC) has a poor prognosis, with frequent early metastatic recurrence after curative resection. Peritoneal metastasis (PM) is particularly difficult to diagnose and predict. While intraoperative lavage cytology (CY) is a standard method to detect PM, its utility remains unclear in PHC.
Kentaro Miyake, Ryusei Matsuyama, Yusuke Nakazaki, Kota Sahara, Tomoaki Takahashi, Yutaro Kikuchi, Yasuhiro Yabushita, Yu Sawada, Yuki Homma, Itaru Endo   +9 more
wiley   +1 more source