Results 201 to 210 of about 84,483 (336)

In Vitro Expansion and Transduction of Primary NK Cells Using Feeder Cells Expressing Costimulatory Molecules and IL‐21

open access: yesCancer Science, EarlyView.
Our findings show that feeder cells expressing CD80, 41BBL and membrane‐bound IL‐21 promote optimal NK cell expansion. We also evaluated CAR transduction efficiency into expanded NK cells using different lentiviral vectors. The results indicate that NK cells transduced with the BaeV lentivirus exhibit high cytotoxicity toward target cells.
Thi Bao Tram Tran   +12 more
wiley   +1 more source

Combining Procalcitonin and Calcitonin for the Diagnosis of Medullary Thyroid Cancer: A Two‐Step Approach

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective Calcitonin (CT) represents the most important biochemical marker of medullary thyroid cancer (MTC), but has certain limits. Procalcitonin (ProCT) has been recognized as an alternative or additional marker for MTC. The aim of the study is to evaluate prospectively the role of ProCT combined with CT in the identification of MTC ...
Cristina Clausi   +13 more
wiley   +1 more source

Avidin-gated mesoporous silica nanoparticles for signal amplification in electrochemical biosensor

open access: yesElectrochemistry Communications, 2019
We report herein a novel sensing strategy for electrochemical biosensors, by using mesoporous silica nanoparticles loaded with the redox probe methylene blue and capped with an avidin/imminobiotin stimulus-responsive gate-like ensemble as signal ...
Sandra Jimenez-Falcao   +5 more
doaj  

Measurement of Carcinoembryonic Antigen

open access: yesClinical Chemistry, 1973
Martin Fleisher   +3 more
openaire   +3 more sources

Obstructive sleep apnea is associated with impaired insulin clearance and hepatic insulin sensitivity in paediatric obesity

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
Abstract Aims Obstructive sleep apnea (OSA) affects up to 40% of children and adolescents with obesity and is linked to hyperinsulinism. However, the mechanisms underpinning this association remain unclear. The study aims to assess the three key determinants of hyperinsulinemia: insulin clearance, secretion, and sensitivity in paediatric patients with ...
Giuseppina Rosaria UMANO   +11 more
wiley   +1 more source

Reirradiation: Standards, challenges, and patient‐focused strategies across tumor types

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Reirradiation (reRT), defined as administering a course of radiation therapy to a specific area previously irradiated, is an evolving treatment strategy for locoregionally recurrent cancer that offers significant potential and poses inherent challenges.
Arnaud Beddok   +21 more
wiley   +1 more source

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