Results 91 to 100 of about 280,367 (274)

Fluorescence in situ hybridization is superior for monitoring Epstein Barr viral load in infectious mononucleosis patients

BMC Infectious Diseases, 2017
Background Epstein Barr virus (EBV) plays a causal role in some diseases, including infectious mononucleosis, lymphoproliferative diseases and nasopharyngeal carcinoma.
Pengfei Cao, Meili Zhang, Wei Wang, Yafei Dai, Buqing Sai, Jun Sun, Lujuan Wang, Fan Wang, Guiyuan Li, Juanjuan Xiang   +9 more
doaj   +1 more source

CXCL6 Reshapes Lipid Metabolism and Induces Neutrophil Extracellular Trap Formation in Cholangiocarcinoma Progression and Immunotherapy Resistance

Advanced Science, EarlyView.
CXCL6's function in cholangiocarcinoma is underexplored. Here it is discovered that CXCL6 is upregulated in cholangiocarcinoma tissues and promotes proliferation and metastasis of it. CXCL6 functions through the CXCR1/2‐JAK‐STAT/PI3K axis and reshaping tumor lipid metabolism.
Tian He, Zi‐Yi Wang, Bin Xu, Cheng‐Jie Zhong, Lu‐Na Wang, Huan‐Chen Shi, Zi‐Yue Yang, Shi‐Qi Zhou, Hui Li, Bo Hu, Xiao‐Dong Zhu, Ying‐Hao Shen, Jian Zhou, Jia Fan, Hui‐Chuan Sun, Cheng Huang   +15 more
wiley   +1 more source

Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with carcinogenesis [PDF]

BMC Bioinformatics 2006, 7:413, 2006
Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several investigations support the view that common fragile sites play a role in carcinogenesis.
arxiv  

Plasmonic Molecular Entrapment for Label‐Free Methylated DNA Detection and Machine‐Learning Assisted Quantification

Advanced Science, EarlyView.
Plasmonic molecular entrapment (PME) is label‐free detection and quantification method for DNA methylation. This technique provides direct hotspot site generation around target analytes, overcoming mismatch geometrical properties. The PME demonstrates superior SERS performance and quantification capability, offering promising potential for epigenetic ...
Muhammad Shalahuddin Al Ja'farawy, Vo Thi Nhat Linh, Chaewon Mun, Jun‐Yeong Yang, Jun Young Kim, Rowoon Park, Sung‐Gyu Park, Dong‐Ho Kim, Min‐Young Lee, Ho Sang Jung   +9 more
wiley   +1 more source

Vertebrate Radiobiology: Histopathology and Carcinogenesis [PDF]

, 1953
J. Fürth, A. C. Upton
openalex   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

Inhibition of Rho GEFs attenuates pulmonary fibrosis through suppressing myofibroblast activation and reprogramming profibrotic macrophages

Cell Death and Disease
Idiopathic pulmonary fibrosis has a poor prognosis, with existing medications only partially alleviating symptoms, highlighting the urgent need for new therapeutic approaches.
Chengju Luo, Chenqi Huang, Yuqi Zhu, Yuxin Zhou, Yansheng Qiao, Chenxiao Shi, Yuan Gao, Yongjian Guo, Libin Wei   +8 more
doaj   +1 more source

Emerging roles of lipid metabolism in cancer metastasis

Molecular Cancer, 2017
Cancer cells frequently display fundamentally altered cellular metabolism, which provides the biochemical foundation and directly contributes to tumorigenicity and malignancy.
Xiangjian Luo, Can Cheng, Zheqiong Tan, Namei Li, Min Tang, Lifang Yang, Ya Cao   +6 more
doaj   +1 more source

Epidermal Transplantation during Chemical Carcinogenesis [PDF]

, 1950
R. E. Billingham, J. W. Orr, D. L. Woodhouse   +2 more
openalex   +1 more source

Dynamic network and epigenetic landscape model of a regulatory core underlying spontaneous immortalization and epithelial carcinogenesis [PDF]

arXiv, 2016
Tumorigenic transformation of human epithelial cells in vitro has been described experimentally as the potential result of a process known as spontaneous immortalization. In this process a generic series of cell state transitions occur in which normal epithelial cells acquire a senescent state, later surpassed to attain first a mesenchymal state and ...
arxiv