Heteroaromatic Hybrid Benzimidazole/Oxadiazole (BZ/OZ) Ligand and Its Sm(III) Complex: Study of Their Antibacterial Activity, Toxicological Prediction and Interaction with Different Model Membranes [PDF]
Two heteroaromatic hybrid compounds were synthesized and characterized using various analytical techniques. The results indicate that the benzimidazole/oxadiazole (BZ/OZ) metal derivative exhibits a tridentate coordination mode, where the carbonyl ...
Alberto Aragón-Muriel +5 more
doaj +2 more sources
Content analysis of food advertisements on Iran broadcasting television channels [PDF]
Background: Most advertised foods are cariogenic. Analyzing the content of ads can provide essential perspectives on characteristics of ads and assist in reducing the cariogenic food advertisements, consequently improving oral health. This study aimed to
Zahra Mohammadzadeh +3 more
doaj +2 more sources
In silico study of the toxicity of hyperforin and its metabolites [PDF]
St. John’s wort is a medicinal herb well-known for its antidepressant, anti-inflammatory, antimycotic, and wound-healing properties. Hyperforin, the major phloroglucinol derivative, has been implicated as one of the main contributors to these therapeutic
Ivelin Iliev +3 more
doaj +3 more sources
Genotoxicity analysis and identification of citrinin based on a systematic literature search
Citrinin (CIT) is a mycotoxin produced by several species of the genera Aspergillus, Penicillium, and Monascus, and it often contaminates grains and grain products.
WANG Kexin +4 more
doaj +1 more source
The High Performance of Diethylhydroxylamine in Comparison with Hydrazine for the Removal of Dissolved Oxygen from Boilers of Power Plant [PDF]
In boilers and hot water heating systems, hydrazine is used as one of the powerful reducing agents for eliminating oxygen. Due to the toxicity and carcinogenicity of this material, a suitable replacement named diethylhydroxylamine (DEHA) can be used ...
Majid Sarmadi +3 more
doaj +1 more source
Short-term carcinogenicity study of N-methyl-N-nitrosourea in FVB-Trp53 heterozygous mice.
Carcinogenicity tests predict the tumorigenic potential of various substances in the human body by studying tumor induction in experimental animals. There is a need for studies that explore the use of FVB/N-Trp53em2Hwl/Korl (FVB-Trp53+/-) mice, created ...
Na-Won Kim +8 more
doaj +1 more source
The Role of Cytokines and Pattern Recognition Receptors in Inflammation Caused by Helicobacter pylori Infection in Gastric Cancer [PDF]
One of the most common and most critical mortality causes in modern society is gastrointestinal (GI) cancer. Helicobacter pylori is one of the most potent risk factors of gastric cancer. This bacterium can suppress the immune system by various pathogenic
Abbas Ganjali +4 more
doaj +1 more source
Toxicology of iodine: A mini review [PDF]
Iodine is necessary for all living organisms. Deficiency of iodine in the organism leads to various diseases (including mental) and increased rates of cancer.
Ilin Alexander, Nersesyan Armen
doaj +1 more source
DNA adducts as link between in vitro and in vivo carcinogenicity – A case study with benzo[a]pyrene
To reduce the need for animal tests, in vitro assays are often used as alternative methods. To derive toxic doses for higher tier organisms from in vitro assay results, quantitative in vitro-in vivo extrapolation (qIVIVE) based on physiological-based ...
Martin Gerhards +4 more
doaj +1 more source
Background Conflicting results between bacterial mutagenicity tests (the Ames test) and mammalian carcinogenicity tests might be due to species differences in metabolism, genome structure, and DNA repair systems. Mutagenicity assays using human cells are
Manabu Yasui +29 more
doaj +1 more source

