Results 171 to 180 of about 13,945 (267)

Genotoxic carcinogenicity of pyrrolizidine alkaloids: relevance of potency factors for the risk assessment. [PDF]

Arch Toxicol
Sachse B, Hessel-Pras S, Schäfer B.
europepmc   +1 more source

Tests on the pill for carcinogenicity. [PDF]

BMJ, 1972
openaire   +2 more sources

Evaluation of DNA/Chromosome Integrity and Cell Death in Human Metabolically Noncompetent and Competent Cells Exposed to N′‐(3,5‐Difluorobenzylidene)Pyridine‐4‐Carbohydrazide

Journal of Applied Toxicology, EarlyView.
ABSTRACT The N‐acylhydrazone scaffold is recognized as a privileged structure for the design of bioactive substances with increasing applications in medicinal chemistry research. Ensuring the safety of newly developed molecules is a critical step for both human health and environmental protection. Accordingly, this study aimed to evaluate the cytotoxic
Larissa Ribeiro Canuto Santos, Jéssica Natalia Barbosa de Almeida, Camila Cavalleiro Frias, Wanda Pereira Almeida, Edson Luis Maistro   +4 more
wiley   +1 more source

Re-evaluation of sucralose (E 955) as a food additive and evaluation of a new application on extension of use of sucralose (E 955) in fine bakery wares. [PDF]

EFSA J
EFSA Panel on Food Additives and Flavourings (FAF), Castle L, Andreassen M, Aquilina G, Bastos ML, Boon P, Fallico B, FitzGerald R, Fernandez MJF, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Houdeau E, Kurek M, Louro H, Morales P, Passamonti S, Batke M, Dourus A, Chipman J, Crebelli R, Fürst P, Halldorsson T, Mirat M, Mortensen A, Wright M, Lindtner O, Barmaz S, Civitella C, Horvath Z, Levorato S, Mazzoli E, Rasinger JD, Rincon AM, Smeraldi C, Tard A, Lodi F.   +36 more
europepmc   +1 more source

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

Journal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal, Abdullah Burak Karaduman, Büşra Korkut Çelikateş, Merve Güven, Özlem Atlı‐Eklioğlu, Sinem Ilgın   +5 more
wiley   +1 more source

Tracing pesticides through terrestrial food webs with wildlife at risk. [PDF]

iScience
Chen S, Li Z.
europepmc   +1 more source

Synthesis and Characterization of Juglone‐Derived cu (II), Mn (II) and Zn (II) Complexes and Investigation of Their Cytotoxic Activities Against Lung and Colon Cancer Cells in Vitro and in Silico

Journal of Applied Toxicology, EarlyView.
ABSTRACT Three new Zn (II), Cu (II) and Mn (II) complexes have been synthesized from 5‐hydroxy‐1,4‐naphthoquinone (HNQ). Elemental analysis, magnetic susceptibility, UV–Vis, IR and Mass spectrometry have all been used to explore the structural characterization of these compounds.
Mustafa Öztatlıcı, Turan Birimoğlu, Semih Güler, Rukiye Betül Çolaksel, Mehmet Tahir Husunet, Mehmet Sönmez   +5 more
wiley   +1 more source

Impact of carbon-based fibers morphologies on their carcinogenic potential. [PDF]

Part Fibre Toxicol
Wagner A, Schulz F, Meyer-Plath A, Dahlmann F, Rittinghausen S, Schaudien D.   +5 more
europepmc   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

Journal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye, M. B. Komane, A. P. Manyisane, R. Manganyi   +3 more
wiley   +1 more source

Integration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of 4 small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities. [PDF]

Toxicol Sci
Guo X, Seo JE, Xu H, Yan J, Malhi P, Atrakchi AH, McGovern T, Davis Bruno KL, Heflich RH, Chen T.   +9 more
europepmc   +1 more source