ABSTRACT Background We compared treatment delays, costs, and management impact between oropharyngeal squamous cell carcinoma (OPSCC) patients undergoing in‐office versus general anesthesia panendoscopy‐guided biopsies in two large tertiary centers in a public healthcare system. Methods All OPSCC patients included were treated between 2010 and 2024 with
Samuel Bellavance +10 more
wiley +1 more source
An Industry Perspective on Key Considerations for the ICH S13 Guidance: Nonclinical Safety Evaluations of Oligonucleotide-Based Therapeutics. [PDF]
Sisler JD +12 more
europepmc +1 more source
Re: Arsenic carcinogenicity testing. [PDF]
openaire +1 more source
ABSTRACT Introduction Oral cavity cancer (OCC) incidence is rising among non‐smokers and younger individuals without traditional risk factors. While carcinogenic exposures such as tobacco and alcohol are well studied, the association between unhealthy dietary patterns and OCC has been minimally explored.
Mateo Useche +8 more
wiley +1 more source
Oncotransformation in Bhas 42 Cell Transformation Assay by Typical Non-Genotoxic Carcinogens, PFOA and PFOS, and Time-Course Transcriptome Analysis. [PDF]
Ohmori K.
europepmc +1 more source
Toward Explainable Carcinogenicity Prediction: An Integrated Cheminformatics Approach and Consensus Framework for Possibly Carcinogenic Chemicals. [PDF]
Duy HA, Srisongkram T.
europepmc +1 more source
Naphthalene: MAK Value Documentation, addendum - Translation of the German version from 2022. [PDF]
Hartwig A +1 more
europepmc +1 more source
Tetrabromobisphenol A: MAK Value Documentation - Translation of the German version from 2023. [PDF]
Hartwig A, MAK Commission .
europepmc +1 more source
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia +4 more
wiley +1 more source
Guidance on the scientific data requirements for an application for authorisation of a food additive submitted under Regulation (EC) No 1331/2008. [PDF]
EFSA Panel on Food Additives and Flavourings (FAF) +30 more
europepmc +1 more source

