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Statement on the use and interpretation of the margin of exposure approach. [PDF]
EFSA Scientific Committee +26 more
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TESTS FOR CARCINOGENICITY OF ASBESTOS*
W E, Smith +3 more
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Carcinogenicity Testing of Drugs
JAMA: The Journal of the American Medical Association, 1980To the Editor.— I agree with John C. Ballin, MD (242:26, 1979), that the results of studies in which large doses are given to animals for a lifetime do not necessarily mean that "such drugs or chemicals are carcinogenic in man when taken according to label directions." But the studies do not necessarily mean that such drugs or chemicals are not ...
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Carcinogenicity testing of drugs
1985The dramatic advances in medicine in the last fifty years have stemmed in large part from extensive research to discover new effective medications for controlling and treating many types of diseases that afflict mankind. In the development of new drugs, an increasingly important aspect is to predict and assess any adverse effects that the products ...
G M, Williams, J H, Weisburger
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Carcinogenicity Testing of Drugs
JAMA: The Journal of the American Medical Association, 1979To the Editor.— The National Cancer Institute (NCI) has begun a long-term project of testing commonly used drugs for their possible carcinogenic effect in animals. In conducting these tests, the NCI uses a standard protocol that involves giving drugs for long periods (generally lifetime feeding) in large doses to mice, rats, and other experimental ...
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Australasian Journal of Dermatology, 1969
Summary A carcinogen in the form of whole tobacco smoke condensate was applied to the skin of a group of human subjects most of whom had suffered from bronchogenic carcinoma. One week later the epidermal density was estimated on the area exposed to the carcinogen and compared with, the density of unexposed epidermis in the same subject.
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Summary A carcinogen in the form of whole tobacco smoke condensate was applied to the skin of a group of human subjects most of whom had suffered from bronchogenic carcinoma. One week later the epidermal density was estimated on the area exposed to the carcinogen and compared with, the density of unexposed epidermis in the same subject.
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The peritoneal cell carcinogenicity test
Mutation Research Letters, 1986The peritoneal cell carcinogenicity test, which is a new short-term in vivo-in vitro transformation test invented by Nashed (1981), was evaluated in the present report. The experimental design and materials used were as close as possible to those used by Nashed (1981).
Nielsen, Jesper B., Andersen, Ole
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