ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza +2 more
wiley +1 more source
Structural Characterization, Toxicity Assessment and Molecular Modeling of Forced Degradation Products of Siponimod. [PDF]
Liang Y, Zhang T, Zhang D, Jin B, Ma C.
europepmc +1 more source
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara +4 more
wiley +1 more source
Wildland-urban interface co-combustion of biomass, synthetic polymeric materials, and lithium-ion batteries generates a new class of ultrafine soot-metal-PAH hybrid particles. [PDF]
Rumi MJU +7 more
europepmc +1 more source
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima +4 more
wiley +1 more source
Tissue and Sex-Specific Performance of a Cancer Driver Based Biomarker in rasH2-Tg Mice. [PDF]
Harris KL, Faske JB, Gong B, Parsons BL.
europepmc +1 more source
Testing for carcinogenicity of pharmaceuticals.
T, Usui, H, Masuda
openaire +1 more source
Editorial: Application of new approach methodologies in toxicological assessment of next-generation tobacco and nicotine products. [PDF]
Lemus R +4 more
europepmc +1 more source
A Statistical Exploration of QSAR Models in Cancer Risk Assessment: A Case Study on Pesticide-Active Substances and Metabolites. [PDF]
Greco S +3 more
europepmc +1 more source
Exploring Retene's Tumour-Initiating Potential: Integrating Computational and Experimental Approaches. [PDF]
da Silva Junior FC +3 more
europepmc +1 more source

