Results 241 to 250 of about 2,980,265 (315)

Naphtha (petroleum), hydrotreated heavy: MAK Value Documentation, addendum - Translation of the German version from 2025.

MAK Collect Occup Health Saf
Hartwig A, MAK Commission.
europepmc   +1 more source

DrugDL: dual-modal deep learning framework for multi-property drug prediction and targeted therapy discovery. [PDF]

Bioinformatics
Zhang Q, Yu X, Wei Y, Xia Y, Shen LC, Wang ZH, Shen HB, Yu DJ.   +7 more
europepmc   +1 more source

Bisphenol M Induces Dose‐Dependent Hepatic Injury and Fibrotic Remodeling in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The safety of bisphenol analogs as alternatives to bisphenol A (BPA) is increasingly concerning. This study investigated the hepatotoxic effects of bisphenol M (BPM), a widely used BPA substitute, in 6‐week‐old female BALB/c mice exposed to 2.5, 5, and 10 mg/kg/day intraperitoneally for 14 days. Hepatic changes were assessed via histopathology,
Muhammed Canik, Asuman Deveci Ozkan, Tuğba Kotil, Nazan Deniz Yön   +3 more
wiley   +1 more source

Reassessing the carcinogenic potential of dibutyl hydrogen phosphate: new insight from repeated-dose toxicity studies. [PDF]

Arch Toxicol
Fayyaz S, Sauer UG, Li Q, Guthmann H, Lichtblau A, Hufnagel M, Grimm FA.   +6 more
europepmc   +1 more source

Repeated Exposure to a Hair Bleaching Mixture Alters cGAS–STING Pathway Transcripts in Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT Hair bleaching products commonly contain ammonia and hydrogen peroxide, chemicals capable of generating reactive oxygen species (ROS). However, their effects on innate immune signaling pathways associated with DNA damage remain poorly understood.
Leticia Rodrigues Sampaio, Marjori Lima Boblitz Parente, Ronald Feitosa Pinheiro   +2 more
wiley   +1 more source

The history of statistics in statistically valid regulation. [PDF]

BJHS Themes
Phillips CJ.
europepmc   +1 more source

Cytotoxic and Genotoxic Effects in Buccal Cells of Sandstone Quarry Workers

Journal of Applied Toxicology, EarlyView.
ABSTRACT Mineral extraction poses significant occupational health risks, particularly from respirable crystalline silica exposure. Sandstone quarrying generates substantial dust, yet evidence of its genotoxic effects remains limited. This study investigated cytogenotoxic damage in sandstone quarry workers from southern Brazil using the buccal ...
Ana Carolina de Quadros Duarte, Maria Isabela Toniazzo, Rayne Vallada da Luz, Cleisson Guimarães Bueno, Daniela Müller de Quevedo, Luciano Basso da Silva, Daiane Bolzan Berlese   +6 more
wiley   +1 more source

Antidiabetic potential of a novel hydroxyphenyl-bi-benzopyran-hexol compound from Cassia fistula as an α-amylase inhibitor: Integrated in silico screening and in vitro validation using a nonlinear regression model. [PDF]

J Ayurveda Integr Med
Baskar R, Harini M, Selvapriya SS, Hemadevi T, Rajalakshmi A, Kavitha K, Puvanakrishnan R, Ramesh B.   +7 more
europepmc   +1 more source

Metal Accumulation, Liver Histopathology, and Human Health Risk Assessment Across Different Trophic Guilds in a Mining‐Affected Neotropical River

Journal of Applied Toxicology, EarlyView.
ABSTRACT Metal pollution in aquatic environments represents a recurring global concern; however, traditional paradigms often assume linear bioaccumulation patterns that may fail under catastrophic contamination scenarios. This study evaluated metal concentrations in water, sediment, and tissues of 10 fish species from different trophic guilds in the ...
Breno Thuller, Alessandro Loureiro Paschoalini, Fabio Pereira Arantes, Cristiano Schetini de Azevedo, Elizete Rizzo, Nilo Bazzoli   +5 more
wiley   +1 more source

Oncotransformation in Bhas 42 Cell Transformation Assay by Typical Non-Genotoxic Carcinogens, PFOA and PFOS, and Time-Course Transcriptome Analysis. [PDF]

Biomolecules
Ohmori K.
europepmc   +1 more source