Results 231 to 240 of about 33,845 (314)

Nitrate measurement and age-specific carcinogenic and non-carcinogenic risk assessment in commonly consumed vegetables from Khuzestan Province, Iran. [PDF]

Sci Rep
Pakravan N, Noori SMA, Salehcheh M, Darvishnejad M, Seyedtabib M, Mohammadi E, Khodayar MJ.   +6 more
europepmc   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, EarlyView.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

An integrated multi-method assessment of toxic element contamination and associated ecological and health risks in heavily contaminated paddy soils of Bangladesh. [PDF]

Environ Sci Pollut Res Int
Hasan MS, Nakano A, Johannes LP, Nguyen TA, Xuan TD, Kibria MG, Thinh NV.   +6 more
europepmc   +1 more source

Beyond Tradition: An Integrated Toxicological, Ecological, and Public Health Perspective on Aristolochic Acids

Journal of Applied Toxicology, EarlyView.
ABSTRACT Aristolochia species have long been used in traditional medicine for their presumed anti‐inflammatory, analgesic and antimicrobial properties. However, extensive toxicological and epidemiological evidence now demonstrates that these plants contain aristolochic acids (AAs) I and II, highly potent nephrotoxic, genotoxic, and carcinogenic ...
Victor Ventura de Souza, Lara Rodrigues De Andrade, Tatiana da Silva Souza   +2 more
wiley   +1 more source

<i>N</i>,<i>N'</i>,<i>N</i>''-Tris(β-hydroxypropyl)hexahydro-1,3,5-triazine: MAK Value Documentation - Translation of the German version from 2023. [PDF]

MAK Collect Occup Health Saf
Hartwig A, MAK Commission https://www.dfg.de/de/ueber-uns/gremien/senat/arbeitsstoffe/mitglieder.   +1 more
europepmc   +1 more source

Health Biomarkers of Pesticide Exposure in Rural Populations of Santa Fe, Argentina: Oxidative Stress and Genotoxicity

Journal of Applied Toxicology, EarlyView.
ABSTRACT The present study aimed to quantify pesticide residues in environmental matrices and plasma and to evaluate their potential effects on oxidative stress and DNA damage in rural populations of Santa Fe province. Soil and rainwater samples were collected, and biological samples and semistructured surveys were obtained from volunteers in three ...
María Priscila Dechiara, Carlina Leila Colussi, Lucía Magdalena Odetti, Damián Marino, María Fernanda Simoniello   +4 more
wiley   +1 more source

Statement on the use and interpretation of the margin of exposure approach. [PDF]

EFSA J
EFSA Scientific Committee, Bennekou SH, Allende A, Bearth A, Casacuberta J, Castle L, Coja T, Crépet A, Halldorsson T, Hoogenboom LR, Knutsen H, Lambré C, Nielsen S, Turck D, Civera AV, Villa R, Jokelainen P, Zorn H, Benford D, Fitzgerald R, Meek B, Mortensen A, Sand S, Testai E, Manini P, Paini A, Schrenk D.   +26 more
europepmc   +1 more source

Subchronic Exposure to Arsenic and Nickel Triggers Nitrosative Stress and Histological Alterations in the Rat Liver

Journal of Applied Toxicology, EarlyView.
ABSTRACT Environmental exposure to heavy metals poses a threat to human health. Several studies documented harmful effects on the liver after arsenic and nickel exposure at concentrations beyond permissible limits. Nevertheless, the impact of a simultaneous exposure to both elements on hepatic biochemistry and histology remains unelucidated. Therefore,
Thainá Iasbik‐Lima, Luiz Otávio Guimarães‐Ervilha, Isabela Pereira da Silva Bento, Renê Chagas da Silva, Mariana Machado‐Neves   +4 more
wiley   +1 more source

A Statistical Exploration of QSAR Models in Cancer Risk Assessment: A Case Study on Pesticide-Active Substances and Metabolites. [PDF]

Toxics
Greco S, Bossa C, Battistelli CL, Giuliani A.   +3 more
europepmc   +1 more source

Bisphenol A Induces DNA Damage and Differential Cytotoxicity in Thyroid Cells: High‐Dose Effects Challenge Regulatory Thresholds

Journal of Applied Toxicology, EarlyView.
ABSTRACT Bisphenol A (BPA), a ubiquitous environmental endocrine disruptor, has been implicated in carcinogenesis; however, its effects on thyroid cells remain unclear. This study investigated BPA‐induced cytotoxicity and genotoxicity in thyroid cell lines, including normal follicular (Nthy‐ori 3‐1), papillary carcinoma (TPC‐1 and BCPAP) and anaplastic
Izabela Fernanda Dal' Bó, Natássia Elena Bufalo, Valdemar Máximo, Laura Sterian Ward   +3 more
wiley   +1 more source