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Addressing Immune Response Dysfunction in an Integrated Approach for Testing and Assessment for Non-Genotoxic Carcinogens in Humans: A Targeted Analysis. [PDF]
Colacci A, Corsini E, Jacobs MN.
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Potential mammary carcinogens used in food contact articles: implications for policy, enforcement, and prevention. [PDF]
Parkinson LV, Geueke B, Muncke J.
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Carcinogenicity of sterigmatocystin
Food and Cosmetics Toxicology, 1968Abstract The mycotoxin, sterigmatocystin, was administered to rats in doses of 0·15–2·25 mg/day by gavage or in the diet for 52 wk. Eight rats which received a high dose (1·5–2·25 mg/day) of sterigmatocystin died between wk 5 and 18, while 39 out of the 50 treated rats surviving to wk 42 eventually developed hepatocellular carcinoma. Of these, 31 had
J. J. van der Watt, I.F.H. Purchase
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Dietary Carcinogens and Anti-Carcinogens
Journal of Toxicology: Clinical Toxicology, 1984The scientific understanding of cancer and degenerative disease is being aided by new methodologies which are now used to approach the problem of environmental and occupational carcinogens and anticarcinogens. This paper reviews these powerful new tools and relates them to "natural" mutagens and carcinogens in food.
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Chemico-Biological Interactions, 2021
Current regulatory cancer risk assessment principles and practices assume a linear dose-response relationship-the linear no-threshold (LNT) model-that theoretically estimates cancer risks occurring following low doses of carcinogens by linearly extrapolating downward from experimentally determined risks at high doses.
Nicholas D. Priest+2 more
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Current regulatory cancer risk assessment principles and practices assume a linear dose-response relationship-the linear no-threshold (LNT) model-that theoretically estimates cancer risks occurring following low doses of carcinogens by linearly extrapolating downward from experimentally determined risks at high doses.
Nicholas D. Priest+2 more
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Carcinogens and Anticarcinogens
1986There is the potential for major progress in the prevention of cancer in the next 5 or 10 years. In the short term, progress in the prevention of cancer depends on a better understanding of some of the risk factors and antirisk factors for the major human cancers.
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Mutagens, Carcinogens, and Anti-Carcinogens
1982Mutagens and carcinogens in the environment represent a potential hazard, and it is important to screen large numbers of compounds and mixtures of compounds to which humans are exposed. However, it is Impractical for both technical and monetary reasons to do the bulk of mutagen screening by using mammals.
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