Results 51 to 60 of about 1,853,915 (311)

Clinical features and diagnostic imaging of cholangiolocellular carcinoma compared with other primary liver cancers: a surgical perspective

Technology in Cancer Research & Treatment, 2020
Background and Objectives: Although cholangiolocellular carcinoma is considered a combined hepatocellular and cholangiocarcinoma, we feel that this classification is not appropriate.
Hiroyuki Takamura PhD, MD, Ryousuke Gabata MD, Yoshinao Obatake PhD, MD, Shinichi Nakanuma PhD, MD, Hironori Hayashi PhD, MD, Kazuto Kozaka PhD, MD, Motoko Sasaki PhD, MD, Mitsuyoshi Okazaki PhD, MD, Takahisa Yamaguchi PhD, MD, Hiroyuki Shimbashi PhD, MD, Shiro Terai PhD, MD, Koichi Okamoto PhD, MD, Isamu Makino PhD, MD, Jun Kinoshita PhD, MD, Keishi Nakamura PhD, MD, Tomoharu Miyashita PhD, MD, Hidehiro Tajima PhD, MD, Itasu Ninomiya PhD, MD, Sachio Fushida PhD, MD, Azusa Kitao PhD, MD, Masaaki Kitahara PhD, MD, Kuniaki Arai PhD, MD, Taro Yamashita PhD, MD, Tatsuya Yamashita PhD, MD, Hiroko Ikeda PhD, MD, Yasunori Satoh PhD, MD, Kenichi Harada PhD, MD, Syuichi Kaneko PhD, MD, Toshihumi Gabata PhD, MD, Tateo Kosaka PhD, MD, Tetsuo Ohta PhD, MD   +30 more
doaj   +1 more source

Microenvironment and tumor cells: two targets for new molecular therapies of hepatocellular carcinoma. [PDF]

, 2018
Hepatocellular carcinoma (HCC), is one of the most frequent human cancer and is characterized by a high mortality rate. The aggressiveness appears strictly related to the liver pathological background on which cancer develops.
Amicone, Laura, Marchetti, Alessandra
core   +1 more source

Portal vein thrombosis and arterioportal shunts : effects on tumor response after chemoembolization of hepatocellular carcinoma [PDF]

, 2011
AIM: To evaluate the effect of portal vein thrombosis and arterioportal shunts on local tumor response in advanced cases of unresectable hepatocellular carcinoma treated by transarterial chemoembolization.
Abdelaziz, Omar, Ackermann, Hans, Emad-Eldin, Sally, Mohammed, Nour-Eldin Abdelrehim Nour-Eldin, Naguib, Nagy Naguib Naeem, Trojan, Jörg, Vogl, Thomas J.   +6 more
core   +2 more sources

COMPARATIVE STUDY ON LIVER TRANSPLANTATION WITH AND WITHOUT HEPATOCELLULAR CARCINOMA WITH CIRRHOSIS: ANALYSIS OF MELD, WAITING TIME AND SURVIVAL

ABCD: Arquivos Brasileiros de Cirurgia Digestiva, 2016
Background: Liver transplantation is the usual treatment for hepatocellular carcinoma. Aim : To analyze the MELD score, waiting time and three month and one year survival for liver transplantation in cirrhotic patients affected by hepatocellular ...
Alexandre Coutinho Teixeira de FREITAS, Rafael Shinmi SHIGUIHARA, Ruan Teles MONTEIRO, Thiago Linck PAZETO, Júlio Cezar Uili COELHO   +4 more
doaj   +2 more sources

Bioinformatic Analysis and In Vitro and In Vivo Experiments Reveal That Fibrillarin Participates in the Promotion of Lung Metastasis in Hepatocellular Carcinoma

Bioengineering, 2022
Lung metastasis, the most frequent metastatic pattern in hepatocellular carcinoma, is an important contributor to poor prognosis. However, the mechanisms responsible for lung metastasis in hepatocellular carcinoma remain unknown.
Weixin Luo, Shusheng Lin, Yipei Huang, Ke Zhu, Fapeng Zhang, Junlong Lin, Yufei Qin, Ziyu Zhou, Wenrui Wu, Chao Liu   +9 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

FEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Biomarkers and overall survival in patients with advanced hepatocellular carcinoma treated with TGF-βRI inhibitor galunisertib. [PDF]

, 2020
BackgroundTransforming growth factor beta (TGF-β) signalling is involved in the development of hepatocellular carcinoma (HCC). We followed changes in biomarkers during treatment of patients with HCC with the TGF-βRI/ALK5 inhibitor galunisertib ...
Benhadji, Karim A, Cleverly, Ann, Estrem, Shawn T, Faivre, Sandrine, Gane, Ed, Giannelli, Gianluigi, Kelley, Robin K, Lahn, Michael M, Man, Michael, Paradis, Valerie, Raymond, Eric, Santoro, Armando, Smith, Claire, Wang, Shuaicheng   +13 more
core   +2 more sources

Exosomal microRNAs in hepatocellular carcinoma

Cancer Cell International, 2021
Hepatocellular carcinoma is one of the most common malignant tumors worldwide and the fourth leading cause of cancer-related deaths. The prognosis of hepatocellular carcinoma patients is extremely poor due to the occult onset and high metastasis of ...
Chenbin Liu, Han Wu, Yinqi Mao, Wei Chen, Shuying Chen   +4 more
doaj   +1 more source

Autophagy in cancer and protein conformational disorders

FEBS Letters, EarlyView.
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley   +1 more source

Alpha-fetoprotein detection of hepatocellular carcinoma leads to a standardized analysis of dynamic AFP to improve screening based detection [PDF]

, 2016
Detection of hepatocellular carcinoma (HCC) through screening can improve outcomes. However, HCC surveillance remains costly, cumbersome and suboptimal. We tested whether and how serum Alpha-Fetoprotein (AFP) should be used in HCC surveillance.
Ahn, Sang Hoon, Bird, Sheila M., Bird, Thomas G., Blunsum, Andrew, Cusack, Pearce, Dimitropoulou, Polyxeni, Hayes, Peter C., Hey, Shiying, Jenks, Sara J., Kelly, Sarah, Sturgeon, Catharine, Turner, Rebecca M.   +11 more
core   +2 more sources