Results 11 to 20 of about 105,344 (245)
Medullary Thyroid Carcinoma [PDF]
Scandinavian Journal of Surgery, 2004 Medullary thyroid carcinoma (MTC) is subdivided into sporadic (75%) and hereditary (25%) forms. Several germline mutations in the RET proto-oncogene are the source of distinct clinical phenotypes in hereditary MTC including familial MTC (FMTC) and multiple endocrine neoplasia 2A (MEN 2A) and 2B (MEN 2B).
M, Brauckhoff +5 more
+7 more sources
Thyroid: Medullary carcinoma [PDF]
Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2013 Medullary thyroid cancers (MTC) are rare neuroendocrine tumors arising from the parafollicular C-cells of the thyroid. In this review, we provide a general overview of the classification, pathology, and clinical management of MTC. In the latter half, we survey the underlying genetic framework of MTC and its potential implications within a diagnostic ...
Somnay, Y, Schneider, D, Mazeh, H
openaire +3 more sources
Expert Review of Anticancer Therapy, 2023 Medullary thyroid carcinoma (MTC) constitutes approximately 5-10% of all thyroid cancers. Although the tumor forms in the thyroid, it doesn't originate from thyroid cells, but from the C cells or parafollicular cells which produce and release a hormone called calcitonin (CT). Starting from the second half of the 1900s, MTC was progressively studied and
Pelizzo, Maria Rosa +3 more
openaire +4 more sources
Current Opinion in Endocrinology, Diabetes & Obesity, 2021 Purpose of review To summarize recent developments in the diagnosis and management of patients with medullary thyroid cancer (MTC), with a focus on pathogenesis, systemic therapy, and future directions. Recent findings The addition of mutational analysis to cytological assessment of
Tania, Jaber, Ramona, Dadu, Mimi I, Hu
openaire +3 more sources
Urology Case Reports, 2015 Medullary carcinoma is a rare malignant tumor of the kidney. It affects individuals of African descent and all cases reported show evidence of sickle cell trait. We reviewed an unusual carcinoma arising in a white man, the ninth in the literature.
Piergiuseppe Colombo +8 more
doaj +1 more source
IGF-I influences everolimus activity in medullary thyroid carcinoma [PDF]
, 2015 Context: Medullary thyroid carcinoma (MTC) is a rare tumor originating from thyroid parafollicular C cells. It has been previously demonstrated that insulin-like growth factor I (IGF-I) protects MTC from the effects of antiproliferative drugs. Everolimus,
degli Uberti, Ettore C. +9 more
core +1 more source
Hashimoto's Thyroiditis and Medullary Carcinoma of Thyroid
Journal of Nepal Medical Association, 2014 Hashimoto’s thyroiditis has been found to be associated with lymphoma, papillary carcinoma and Hürthle cell neoplasms of thyroid. In contrast, there are only a few reports of co-existence of HT with medullary carcinoma of thyroid.
Senjuti Dasgupta +3 more
doaj +1 more source
Journal of Medical Case Reports, 2013 Introduction Papillary thyroid microcarcinoma has been demonstrated to present in association with medullary thyroid carcinoma, however, medullary thyroid carcinoma and papillary thyroid carcinoma represent rare entities.
Adnan Zaina +4 more
doaj +1 more source
Journal of Medical Case Reports, 2023 Background Medullary carcinoma of the colon is a rare subtype of colorectal cancer that has a unique, and sometimes varied, clinical and histologic profile. It usually presents in adult patients older than 50 years. Here, we report a unique case of young
Fajer Al-Ishaq +6 more
doaj +1 more source
Anaplastic Thyroid Carcinoma Histologically Mimicking a Plasmacytoma. [PDF]
, 2020 Anaplastic (undifferentiated) thyroid carcinoma (ATC) is a rare malignancy which may arise from transformation of a pre-existing differentiated carcinoma. We report the unique case where a lesion of thyroid origin presented with the histological features
Mo, Joshua H +4 more
core +1 more source