Results 91 to 100 of about 28,766 (211)
, 2019 Clinical metagenomic next-generation sequencing (mNGS), the comprehensive analysis of microbial and host genetic material (DNA and RNA) in samples from patients, is rapidly moving from research to clinical laboratories. This emerging approach is changing
Chiu, Charles Y, Miller, Steven A
core
iMetaOmics, Volume 3, Issue 1, March 2026.Schematic of the study design. In this study, we developed a comprehensive unfolded protein response (UPR) gene signature and applied it to systematically characterize the UPR landscape across multiple cancer types. By integrating bulk and single‐cell transcriptomic data, we revealed substantial inter‐ and intra‐tumoral heterogeneity in UPR activity ...
Xinyu Yang +8 more
wiley +1 more source
Phase I study of IMGN901, a CD56-targeting antibody-drug conjugate, in patients with CD56-positive solid tumors. [PDF]
, 2016 Background IMGN901 is a CD56-targeting antibody-drug conjugate designed for tumor-selective delivery of the cytotoxic maytansinoid DM1. This phase 1 study investigated the safety, tolerability, pharmacokinetics, and preliminary activity of IMGN901 in ...
A Ballantyne +34 more
core +3 more sources
Plaque‐type trichoblastoma and its siblings: A (follicular tumour) family history
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ines Bertlich +4 more
wiley +1 more source
Andrology, Volume 14, Issue 3, Page 661-701, March 2026.Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani +6 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 63, Issue 6, Page 778-794, March 2026.Statin therapy in cirrhosis may confer a survival benefit while reducing the risk of hepatic decompensation and hepatocellular carcinoma. ABSTRACT Background The role of statins in cirrhosis remains controversial. Historically restricted due to safety concerns, emerging evidence highlights potential pleiotropic benefits, though effects on mortality and
Bernardo de Faria Moraes +8 more
wiley +1 more source
Clinical case: successful treatment of Merkel cell carcinoma in an 84-year-old patient
Сибирский научный медицинский журналMerkel cell carcinoma is a rare tumour characterized by a high potential for metastasis and local recurrence. The nonspecific clinical picture of the disease often leads to late diagnosis, which creates certain difficulties in the further management of ...
E. E. Babykhin +5 more
doaj +1 more source
Rare Tumors, 2011 Merkel cell carcinoma is a rare tumor frequently involving the skin with an aggressive behavior and fatal outcome. It occurs mostly in the caucasian race between 60-80 years of age and it is rare in children. Herein we report our experience with a highly
Mohammad Reza Farzaneh +2 more
doaj +1 more source
An Updated Review of the Biomarkers of Response to Immune Checkpoint Inhibitors in Merkel Cell Carcinoma: Merkel Cell Carcinoma and Immunotherapy. [PDF]
Cancers (Basel), 2023 Fojnica A +4 more
europepmc +1 more source
Merkel cell polyomavirus and Merkel cell carcinoma [PDF]
Philosophical Transactions of the Royal Society B: Biological Sciences, 2017 Merkel cell polyomavirus (MCPyV) causes the highly aggressive and relatively rare skin cancer known as Merkel cell carcinoma (MCC). MCPyV also causes a lifelong yet relatively innocuous infection and is one of 14 distinct human polyomaviruses species.
openaire +2 more sources