Results 61 to 70 of about 615,884 (310)

Life Threatening haemoptysis in primary lung cancer-signet ring cell carcinoma

open access: yesRespiratory Medicine Case Reports, 2020
Primary signet ring cell carcinoma of the lung is a rare non-small cell carcinoma of the lung with extremely aggressive features and poor prognosis. The diagnosis mainly required tissue biopsy with immunohistochemical analysis and gene mutation studies ...
Shamsuddin Anwar   +4 more
doaj   +1 more source

Long-term survival after an aggressive surgical resection and chemotherapy for stage IV pulmonary giant cell carcinoma [PDF]

open access: yes, 2005
BACKGROUND: Pulmonary giant cell carcinoma is one of the rare histological subtypes with pleomorphic, sarcomatoid or sarcomatous elements. The prognosis of patients with this tumor tends to be poor, because surgery, irradiation and chemotherapy are not ...
Ichinose, Yukito   +6 more
core   +3 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

Surgically resected sarcomatoid carcinoma of the lung: a nationwide retrospective study in 2010

open access: yesBMC Cancer
Background Sarcomatoid carcinoma of the lung is a rare histological type of non-small cell lung cancer with a poor prognosis. We aimed to investigate the clinicopathological characteristics and prognostic factors of surgically resected sarcomatoid ...
Kaoru Kaseda   +12 more
doaj   +1 more source

Non-small cell lung carcinoma in an adolescent manifested by acute paraplegia due to spinal metastases: a case report

open access: yesJournal of Medical Case Reports, 2011
Introduction Bronchial carcinomas in childhood and adolescence are extremely rare; only individual cases have been reported previously. Case presentation We report on a 16-year-old Caucasian German boy with non-small cell lung carcinoma (squamous cell ...
Haffner Dieter   +2 more
doaj   +1 more source

A Case of Advanced Lung Squamous Cell Carcinoma with CLIP1-ALK Fusion Gene

open access: yesChinese Journal of Lung Cancer, 2022
Anaplastic lymphoma kinase (ALK) fusion gene is an important tumor driver gene of non-small cell lung cancer, accounting for about 5% of patients with non-small cell lung cancer, of which 97% are patients with lung adenocarcinoma.
Yue YUAN   +4 more
doaj   +1 more source

Case report: Heterogenous SMARCA4-deficient thoracic non-small cell lung carcinoma with various responses to nivolumab

open access: yesFrontiers in Immunology, 2023
SMARCA4-deficient non-small cell carcinoma is an aggressive neoplasm with poor outcome. Several studies have highlighted its immunochemistry, pathophysiology, and underlying mechanisms, but studies of its definite treatment are few.
Yun-Tzu Lin   +10 more
doaj   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

Multiple intraventricular brain metastasis in a case of non-small cell lung carcinoma

open access: yesVascular Investigation and Therapy, 2019
Intraventricular metastasis is a rare entity encountered in very few malignancies. Although the renal cell carcinoma is the most common primary causing this rare event, due to overall more incidences of lung carcinomas, the intraventricular metastasis by
Rashmeet Kaur   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy