Results 61 to 70 of about 689,752 (349)

Study of PD-L1 Expression in Tumours Based on Site and Histology of Tumour – The Experience of a Tertiary Referral Laboratory

Asian Pacific Journal of Cancer Biology, 2023
Background: PD-L1 IHC test is used as a predictive biomarker using FDA-approved assays to select patients likely to benefit from immunotherapy in several advanced-stage tumors. We aim to present our data regarding the prevalence and expression pattern of
Vinita Pant, Munmun Harlalka
doaj   +1 more source

Molecular pathways and therapeutic targets in lung cancer [PDF]

, 2014
Lung cancer is still the leading cause of cancer death worldwide. Both histologically and molecularly lung cancer is heterogeneous. This review summarizes the current knowledge of the pathways involved in the various types of lung cancer with an emphasis
Bueno, Raphael, Dennis, Phillip A., Hensing, Thomas, Otterson, Gregory A., Salgia, Ravi, Shtivelman, Emma, Simon, George R.   +6 more
core   +2 more sources

MicroRNA-1253 suppresses cell proliferation and invasion of non-small-cell lung carcinoma by targeting WNT5A

Cell Death and Disease, 2018
MicroRNAs (miRNA) are a class of small, noncoding RNA molecules that regulate the expression of target genes. miRNA dysregulation is involved in carcinogenesis and tumor progression.
Mei-yue Liu, Yue Zhang, Jie Zhang, Haifeng Cai, Chao Zhang, Zhao Yang, Y. Niu, Huan Wang, Xiao-mei Wei, Wei Wang, Peng Gao, Hong-min Li, Jinghua Zhang, G. Sun   +13 more
semanticscholar   +1 more source

Pattern of Recurrence after Curative Resection of Local (Stage I and II) Non-Small Cell Lung Cancer: Difference According to the Histologic Type [PDF]

, 2004
The aim of the present study was to evaluate the pattern of recurrence after complete resection of pathological stage I, II non-small cell lung cancer, especially according to the cell type.
Cagini, D'Amico, Ham, Jhingook Kim, Kwhanmien Kim, Martini, Mussi, Ohta, Okada, Ramacciato, Rena, Thomas, Yong Soo Choi, Young Mog Shim   +13 more
core   +2 more sources

A Case Report of Small Cell Lung Carcinoma in a Patient with Progressive Diffuse Sclerosis

Journal of Mazandaran University of Medical Sciences, 2022
Connective tissue diseases, including scleroderma, may be associated with an increased risk of lung cancer. The most common type of lung cancer associated with systemic sclerosis is adenocarcinoma or bronchoalveolar carcinoma, and small cell carcinoma is
Hojatolah Ghorbani, Maryam Mobini, Ehsan Zaboli, Laleh Vahedi Larijani, Hadi Majidi   +4 more
doaj  

A Case of Advanced Lung Squamous Cell Carcinoma with CLIP1-ALK Fusion Gene

Chinese Journal of Lung Cancer, 2022
Anaplastic lymphoma kinase (ALK) fusion gene is an important tumor driver gene of non-small cell lung cancer, accounting for about 5% of patients with non-small cell lung cancer, of which 97% are patients with lung adenocarcinoma.
Yue YUAN, Zheng WANG, Xin NIE, Ping ZHANG, Lin LI   +4 more
doaj   +1 more source

Blood-Derived Exosomal hTERT mRNA in Patients with Lung Cancer: Characterization and Correlation with Response to Therapy

Biomedicines, 2023
Background: Telomerase (human telomerase reverse transcriptase (hTERT) is considered a hallmark of cancer, being active in cancer cells but repressed in human somatic cells. As such, it has the potential to serve as a valid cancer biomarker.
Ofer Rotem, Alona Zer, Lilach Yosef, Einat Beery, Hadar Goldvaser, Anna Gutkin, Ron Levin, Elizabeth Dudnik, Tamar Berger, Meora Feinmesser, Adva Levy-Barda, Meir Lahav, Pia Raanani, Orit Uziel   +13 more
doaj   +1 more source

Plasma lipid biomarker signatures in squamous carcinoma and adenocarcinoma lung cancer patients [PDF]

, 2015
There is a clinical need for reliable biomarkers for lung cancer that permit early diagnosis of the disease and provide prediction of histological phenotype.
AG Serrano, AM Fiorenza, Andrew W. Fogarty, CH Oak, D Kong, David A. Barrett, David R. Baldwin, E Wojcik, GL May, H Ulmer, H Yang, Helen L. Barr, J Castro de, J Chee, J Dong, J Liu, JM Poczobutt, K Yanagisawa, K Yang, L Cheng, M Haag, M Hassanein, M Hassanein, M Murphy, MJ Wakelam, MR Wenk, P Brites, R Angelis de, RA Murphy, RA Murphy, RE Smith, RL Keith, RT Sreseli, S Cedres, Srinivasarao Ravipati, WJ Scott, X Gao, X Zeng, Y Guo, YY Tyurina, ZA Fernandis   +40 more
core   +1 more source

Exosomal proteins as potential diagnostic markers in advanced non-small cell lung carcinoma

Journal of Extracellular Vesicles, 2015
Background Lung cancer is one of the leading causes of cancer-related death. At the time of diagnosis, more than half of the patients will have disseminated disease and, yet, diagnosing can be challenging.
K. R. Jakobsen, B. S. Paulsen, Rikke Bæk, K. Varming, B. Sørensen, M. Jørgensen   +5 more
semanticscholar   +1 more source

Classifying non-small cell lung cancer types and transcriptomic subtypes using convolutional neural networks

J. Am. Medical Informatics Assoc., 2020
OBJECTIVE Non-small cell lung cancer is a leading cause of cancer death worldwide, and histopathological evaluation plays the primary role in its diagnosis.
Kun‐Hsing Yu, Feiran Wang, G. Berry, Christopher Ré, R. Altman, M. Snyder, I. Kohane   +6 more
semanticscholar   +1 more source