Results 221 to 230 of about 89,882 (308)

Oncological outcome of surgical resection for anaplastic carcinoma of the pancreas. [PDF]

Mol Clin Oncol
Sonoda I, Konishi T, Takano S, Takayashiki T, Suzuki D, Sakai N, Hosokawa I, Mishima T, Nishino H, Suzuki K, Nakada S, Ohtsuka M.   +11 more
europepmc   +1 more source

Downregulation of sST2, a decoy receptor for interleukin‐33, enhances subcutaneous tumor growth in murine pancreatic cancer cells

FEBS Open Bio, Volume 15, Issue 12, Page 2031-2044, December 2025.
Subcutaneous implantation of murine Panc02 pancreatic cancer cells depleted of sST2, a soluble decoy receptor for the proinflammatory interleukin‐33 (IL‐33), leads to a decreased number of GLUT4‐positive cancer‐associated adipocytes, reduced levels of the anti‐inflammatory molecule adiponectin, increased phosphorylation of IκBα, elevated Cxcl3 ...
Miho Akimoto, Nobuko Koshikawa, Takao Morinaga, Mimi Tamamori‐Adachi, Atsushi Takatori, Keizo Takenaga   +5 more
wiley   +1 more source

Tumor Budding and E-Cadherin Loss as Robust Prognostic Markers in Pancreatic Ductal Adenocarcinoma: A Study in a Turkish Patient Cohort. [PDF]

Can J Gastroenterol Hepatol
Özcan TB, Pasaoglu E, Gülçiçek OB.
europepmc   +1 more source

Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics

Advanced Materials, Volume 37, Issue 48, December 3, 2025.
Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi, Yadi Fan, Qin Zhang, Yingying Huang, Mo Yang   +4 more
wiley   +1 more source

Molecular mechanisms of RACK1-driven metastasis in pancreatic ductal adenocarcinoma revealed by single-cell RNA sequencing. [PDF]

Discov Oncol
Liu H, Wang T, Cui Y, Zhang B, Shang D, Song H.   +5 more
europepmc   +1 more source

Microneedles From Shape‐Preserving Crosslinked Poly(Vinyl Alcohol) Hydrogels: Minimising Interference in Transdermal Proteomics

Advanced Materials Technologies, Volume 10, Issue 23, December 3, 2025.
Hydrogel‐forming microneedle patches are developed using shape‐preserving PVA‐PVP hydrogels, with and without chitosan, for minimally invasive transdermal protein biomarker sampling. The optimised patches enable efficient interstitial fluid uptake and proteomic analysis, while minimising interference.
Achmad Himawan, Robert Graham, Fabiana Volpe‐Zanutto, Huanhuan Li, Anjali K. Pandya, Andi Nur Aisyah, Rina Agustina, Juan L. Paris, Juan Dominguez‐Robles, Lalitkumar K. Vora, Andi D. Permana, Christopher J. Scott, Ryan F. Donnelly   +12 more
wiley   +1 more source

A pentacyclic triterpene tormentic acid inhibits the proliferation and migration of pancreatic ductal adenocarcinoma cells. [PDF]

Transl Cancer Res
Alshahrani MM, Al Awadh AA.
europepmc   +1 more source

Advancing Clinical Medicine with Raman Spectroscopy: Current Trends and Future Perspectives

Advanced Photonics Research, Volume 6, Issue 12, December 2025.
Raman spectroscopy and microscopy may become excellent tools in clinical medicine, including hematology, oncology, infectious diseases, neurology, gastroenterology, reproductive medicine, rheumatology, and cardiovascular research. However, many challenges such as signal interference, standardization issues, and limited clinical application need to be ...
Jiří Bufka, Lenka Vaňková, Josef Sýkora, Věra Křížková, Jan Schwarz, Petr Bouř   +5 more
wiley   +1 more source

Lactate Activates the HCAR1/β‐Arrestin2/PP2A Signaling Axis to Mediate STAT1/2 Dephosphorylation and Drive Osteosarcoma Progression

Advanced Science, Volume 12, Issue 45, December 4, 2025.
In the present study, it is found that in osteosarcoma, lactate‐activated HCAR1 promotes β‐arrestin 2 translocation from cytoplasm to nucleus. In the nucleus, β‐arrestin 2 recruits PP2A to the activated STAT1/2 dimers, mediating STAT1/2 dephosphorylation and inhibiting the transcription of downstream anti‐oncogenes to promote OS progression.
Zhitao Han, Qi Jia, Guangjian Bai, Zhao Li, Jin Zeng, Zhenhua Wang, Jing Zhang, Jiashi Cao, Baoquan Xin, Yonggang Liu, Jingyu Shen, Lining Wang, Xing Huang, Chunlei Zhang, Kai Tong, Fenglei Dai, Yajie Zhang, Weina Zhu, Songyi Cheng, Yuanming Chen, Xinghai Yang, Guanghui Chen, Zhenhua Zhou, Yong Ma, Weibo Liu, Ting Wang, Tielong Liu   +26 more
wiley   +1 more source

Comparative spatial transcriptomics of pancreatic cancer with ductal and acinar origins in mouse models. [PDF]

Clin Transl Med
Cui M, Bai J, Chang X, Xiao R, Mo S, Soares KC, Yang S, You L, Liao Q, He J, Hu Y, Zhao Y.   +11 more
europepmc   +1 more source