Results 11 to 20 of about 1,472,301 (348)

European Association of Urology Guidelines on Renal Cell Carcinoma: The 2022 Update.

European Urology, 2022
CONTEXT The European Association of Urology (EAU) Renal Cell Carcinoma (RCC) Guideline Panel has prepared evidence-based guidelines and recommendations for the management of RCC.
B. Ljungberg, L. Albiges, Y. Abu-Ghanem, J. Bedke, U. Capitanio, S. Dabestani, S. Fernandez-Pello, R. Giles, F. Hofmann, M. Hora, T. Klatte, T. Kuusk, T. Lam, L. Marconi, T. Powles, R. Tahbaz, A. Volpe, A. Bex   +17 more
semanticscholar   +1 more source

Lenvatinib plus Pembrolizumab or Everolimus for Advanced Renal Cell Carcinoma.

New England Journal of Medicine, 2021
BACKGROUND Lenvatinib in combination with pembrolizumab or everolimus has activity against advanced renal cell carcinoma. The efficacy of these regimens as compared with that of sunitinib is unclear. METHODS In this phase 3 trial, we randomly assigned (
R. Motzer, B. Alekseev, S. Rha, C. Porta, M. Eto, T. Powles, V. Grünwald, Thomas E. Hutson, E. Kopyltsov, M. Méndez-Vidal, V. Kozlov, A. Alyasova, Sung-Hoo Hong, A. Kapoor, T. Alonso Gordoa, J. Merchan, E. Winquist, P. Maroto, J. Goh, Miso Kim, H. Gurney, V. Patel, A. Peer, G. Procopio, T. Takagi, B. Melichar, F. Rolland, U. de Giorgi, Shirley S. Wong, J. Bedke, M. Schmidinger, C. Dutcus, Alan D. Smith, L. Dutta, K. Mody, R. Perini, D. Xing, T. Choueiri   +37 more
semanticscholar   +1 more source

Nivolumab plus Cabozantinib versus Sunitinib for Advanced Renal-Cell Carcinoma.

New England Journal of Medicine, 2021
BACKGROUND The efficacy and safety of nivolumab plus cabozantinib as compared with those of sunitinib in the treatment of previously untreated advanced renal-cell carcinoma are not known.
T. Choueiri, T. Powles, M. Burotto, B. Escudier, M. Bourlon, B. Żurawski, V. O. Oyervides Juarez, J. Hsieh, U. Basso, A. Shah, C. Suarez, A. Hamzaj, J. Goh, C. Barrios, M. Richardet, C. Porta, R. Kowalyszyn, Juan P Feregrino, J. Zolnierek, D. Pook, E. Kessler, Y. Tomita, R. Mizuno, J. Bedke, Joshua Zhang, M. Maurer, B. Simsek, F. Ejzykowicz, G. Schwab, A. Apolo, R. Motzer   +30 more
semanticscholar   +1 more source

Tumor and immune reprogramming during immunotherapy in advanced renal cell carcinoma

Cancer Cell, 2021
Summary Immune checkpoint blockade (ICB) results in durable disease control in a subset of patients with advanced renal cell carcinoma (RCC), but mechanisms driving resistance are poorly understood.
K. Bi, M. X. He, Z. Bakouny, Abhay Kanodia, S. Napolitano, Jingyi Wu, Grace Grimaldi, D. Braun, Michael S. Cuoco, Angie Mayorga, L. Dellostritto, G. Bouchard, J. Steinharter, A. Tewari, N. Vokes, E. Shannon, Maxine Sun, Jihye Park, Steven L. Chang, B. McGregor, Rizwan Haq, Thomas Denize, S. Signoretti, J. Guerriero, S. Vigneau, O. Rozenblatt-Rosen, Asaf Rotem, A. Regev, T. Choueiri, E. V. Van Allen   +29 more
semanticscholar   +1 more source

Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma.

New England Journal of Medicine, 2021
BACKGROUND Patients with renal-cell carcinoma who undergo nephrectomy have no options for adjuvant therapy to reduce the risk of recurrence that have high levels of supporting evidence. METHODS In a double-blind, phase 3 trial, we randomly assigned, in
T. Choueiri, P. Tomczak, S. Park, B. Venugopal, T. Ferguson, Yen‐Hwa Chang, J. Hajek, S. Symeonides, Jae Lyun Lee, N. Sarwar, A. Thiery-Vuillemin, M. Gross-Goupil, M. Mahave, N. Haas, P. Sawrycki, H. Gurney, C. Chevreau, B. Melichar, Evgeniy Kopyltsov, A. Alva, J. Burke, G. Doshi, D. Topart, S. Oudard, H. Hammers, H. Kitamura, J. Bedke, R. Perini, Pingye Zhang, K. Imai, Jaqueline Willemann-Rogerio, D. Quinn, T. Powles   +32 more
semanticscholar   +1 more source

Renal papillary carcinoma developed in a kidney transplant recipient with late IgA-nephropathy [PDF]

, 2016
With improvements in immunosuppressive therapy, patient and graft survival in renal transplant recipients have been prolonged. Increasing donor age and patient survival rates have been related to an increase in the number of de novo tumors ...
BERLOCO, Pasquale Bartolomeo, G. Mennini, GIANNAKAKIS, Konstantinos, GUGLIELMO, NICOLA, MELANDRO, FABIO, NUDO, FRANCESCO, POLI, Luca, PRETAGOSTINI, Renzo   +7 more
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A novel combination of triple metachronous malignancies of the kidney, oropharynx and prostate. A case report [PDF]

, 2015
Synchronous or metachronous malignancies are a rare event, with an incidence rate that increases with age. The present study reports the case of a 70-year-old Caucasian male who was referred to the outpatient office of the Urology Unit, Sapienza ...
Carbone, Antonio, Leto, Antonino, Palleschi, Giovanni, Pastore, ANTONIO LUIGI, Petrozza, Vincenzo, Porta, Natale, Silvestri, Luigi   +6 more
core   +1 more source

Treatment Landscape of Renal Cell Carcinoma

Current Treatment Options in Oncology, 2023
The treatment landscape of renal cell carcinoma (RCC) has evolved significantly over the past three decades. Active surveillance and tumor ablation are alternatives to extirpative therapy in appropriately selected patients.
Yu-Wei Chen, Luke L. Wang, J. Panian, S. Dhanji, I. Derweesh, B. Rose, Aditya Bagrodia, Rana R Mckay   +7 more
semanticscholar   +1 more source

Hereditary papillary renal cell carcinoma primarily diagnosed in a cervical lymph node: a case report of a 30-year-old woman with multiple metastases

BMC Urology, 2013
Background Papillary renal cell carcinoma is a rare cancer. Some cases can be attributed to individuals with hereditary renal cell carcinomas usually consisting of the clear cell subtype.
Behnes Carl Ludwig, Schlegel Christina, Shoukier Moneef, Magiera Isabella, Henschke Frank, Schwarz Alexander, Bremmer Felix, Loertzer Hagen   +7 more
doaj   +1 more source

Case Report: Bilateral Renal Cell Carcinoma With Different Histological and Morphological Features, Clear Cell and Cystic Thyroid-Like Follicular Subtype

Frontiers in Oncology, 2021
Thyroid-like follicular renal cell carcinoma is a rare subtype of renal cell carcinoma that has only been recently recognized, as most cases involve a solid tumor in one kidney.
Jinsong Ni, Ni Cui, Yanfang Wang, Jixuan Liu   +3 more
doaj   +1 more source