Results 31 to 40 of about 357,374 (264)

Quantitative proteomics in resected renal cancer tissue for biomarker discovery and profiling [PDF]

, 2014
BACKGROUND: Proteomics-based approaches for biomarker discovery are promising strategies used in cancer research. We present state-of-art label-free quantitative proteomics method to assess proteome of renal cell carcinoma (RCC) compared with noncancer ...
J T-J Huang, Bray, S E, Fleming, S., Lamont, D J, D J Lamont, Zakikhani, P, P Zakikhani, M A V Mudaliar, Atrih, A, S Fleming, Zakikhani, P., Lamont, D. J., Barton, G.; id_orcid, G Nabi, G Barton, A Atrih, Bray, S. E., Barton, G, Huang, J. T.-J.; id_orcid, Mudaliar, M. A. V., Atrih, A., Fleming, S, Nabi, G, Nabi, G., Huang, J T-J, S E Bray, Mudaliar, M A V   +26 more
core   +1 more source

Differential expression of prognostic proteomic markers in primary tumour, venous tumour thrombus and metastatic renal cell cancer tissue and correlation with patient outcome

, 2013
Renal cell carcinoma (RCC) is the most deadly of urological malignancies. Metastatic disease affects one third of patients at diagnosis with a further third developing metastatic disease after extirpative surgery.
Antony C P Riddick, Stewart Grant D., Laird Alexander, Alexander Laird, Grant D Stewart, Laird, Alexander, O'Mahony, Fiach C, Riddick, Antony C P, Riddick Antony C. P., O’Mahony Fiach C., Harrison David J., Fiach C O'Mahony, Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Riddick, Antony C. P., Nanda Jyoti, Nanda, Jyoti, Stewart, Grant D., O’Donnell Marie, O'Donnell, Marie, Stewart, Grant D, Marie O'Donnell, Harrison, David J.   +24 more
core   +1 more source

Surgical management for upper urinary tract transitional cell carcinoma [PDF]

, 2011
Background Upper tract transitional cell carcinomas (TCC) are uncommon and aggressive tumours. There are a number of surgical approaches to manage this condition including open radical nephroureterectomy and laparoscopic procedures.
El-Mokadem, Ismail, Ismail El-Mokadem, Bhavan Prasad Rai, Nabi, Ghulam, Mike Shelley, Biyani, Chandra S., Bernadette Coles, Chandra S Biyani, Ghulam Nabi, Coles, Bernadette, Shelley, Mike, Rai, Bhavan Prasad   +11 more
core   +1 more source

The use of automated quantitative analysis to evaluate epithelial-to-mesenchymal transition associated proteins in clear cell renal cell carcinoma

, 2012
Background: Epithelial-to-mesenchymal transition (EMT) has recently been implicated in the initiation and progression of renal cell carcinoma (RCC). Some mRNA gene expression studies have suggested a link between the EMT phenotype and poorer clinical ...
Antony C P Riddick, Stewart Grant D., Faratian Dana, Theodoulou Marianna, Grant D Stewart, Dana Faratian (171110), O'Mahony Fiach C., O'Mahony, Fiach C, James Varley (181899), David J. Harrison (171106), Jyoti Nanda (181902), Riddick, Antony C P, Varley James, Marianna Theodoulou, Dana Faratian, Varley, James, Riddick Antony C. P., Harrison David J., Fiach C O'Mahony, Antony C. P. Riddick (145315), Jyoti Nanda, Harrison, David J, David J Harrison, O'Mahony, Fiach C., Faratian, Dana, Riddick, Antony C. P., Nanda Jyoti, Marianna Theodoulou (181905), Grant D. Stewart (145312), Theodoulou, Marianna, Nanda, Jyoti, Stewart, Grant D., James Varley, Stewart, Grant D, Fiach C. O'Mahony (181892), Harrison, David J.   +35 more
core   +1 more source

Surgical excision of renal cell carcinoma with caval and intra-atrial tumour thrombus extension using deep hypothermic circulatory arrest [PDF]

, 2013
Surgery for tumour thrombus extension in Renal Cell Carcinoma may be associated with a good prognosis if no distant metastases are identified and if the thrombus can be completely excised.
Bugeja, Simon, German, Karl Andrew, Zammit, Patrick, Galea, Joseph   +3 more
core  

Resistance after chronic application of the HDAC-inhibitor valproic acid is associated with elevated Akt activation in renal cell carcinoma in vivo

, 2013
Targeted drugs have significantly improved the therapeutic options for advanced renal cell carcinoma (RCC). However, resistance often develops, negating the benefit of these agents.
Eva Juengel, Jasmina Makarević, Axel Haferkamp, Georg Bartsch, Roman A Blaheta, Jüngel, Eva, Nelson, Karen, Blaheta, Roman A., Igor Tsaur, Makarević, Jasmina, Karen Nelson, Tsaur, Igor, Haferkamp, Axel, Bartsch, Georg   +13 more
core   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Prognostic significance of CKAP2L expression in patients with clear cell renal cell carcinoma

Frontiers in Genetics, 2023
Background: Cytoskeleton-associated protein 2-like protein (CKAP2L) is thought to promote the progression of glioma, breast cancer, and ovarian cancer. However, the role of cytoskeleton-associated protein 2-like protein in clear cell renal cell carcinoma
Zhi Liu, Jun Zhang, Deyun Shen, Xuechun Hu, Zongpan Ke, I Nyoman Ehrich Lister, Bungaran Sihombing   +6 more
doaj   +1 more source