Results 41 to 50 of about 1,472,301 (348)

Progressive immune dysfunction with advancing disease stage in renal cell carcinoma.

Cancer Cell, 2021
The tumor immune microenvironment plays a critical role in cancer progression and response to immunotherapy in clear cell renal cell carcinoma (ccRCC), yet the composition and phenotypic states of immune cells in this tumor are incompletely characterized.
D. Braun, Kelly Street, K. Burke, D. Cookmeyer, Thomas Denize, C. B. Pedersen, S. Gohil, N. Schindler, Lucas Pomerance, L. Hirsch, Z. Bakouny, Yue Hou, J. Forman, Teddy Huang, Shuqiang Li, Ang Cui, D. Keskin, J. Steinharter, G. Bouchard, Maxine Sun, E. Pimenta, Wenxin Xu, K. Mahoney, B. McGregor, M. Hirsch, Steven L. Chang, K. Livak, D. McDermott, S. Shukla, L. Olsen, S. Signoretti, A. Sharpe, R. Irizarry, T. Choueiri, Catherine J. Wu   +34 more
semanticscholar   +1 more source

Small bowel intussusception from renal cell carcinoma metastasis : a case report and review of the literature [PDF]

, 2016
Background: Renal cell carcinoma is the most frequent malignant neoplasia of the kidney accounting for 90 % of all renal solid tumors. Metastases from renal cell carcinoma are rarely located in the small bowel and generally their clinical presentation ...
Bellio, Gabriele, Bortul, Marina, Casagranda, Biagio, Cipolat Mis, Tommaso, Dattola, Roberto, Kaso, Gladiola   +5 more
core   +1 more source

COMPREHENSIVE MOLECULAR CHARACTERIZATION OF CLEAR CELL RENAL CELL CARCINOMA

Nature, 2013
Genetic changes underlying clear cell renal cell carcinoma (ccRCC) include alterations in genes controlling cellular oxygen sensing (for example, VHL) and the maintenance of chromatin states (for example, PBRM1).
The Cancer Genome Atlas Research Network
semanticscholar   +1 more source

Epidemiology of Renal Cell Carcinoma

World Journal of Oncology, 2020
Though renal cell carcinoma (RCC) accounts for 2% of global cancer diagnoses and deaths, it has more than doubled in incidence in the developed world over the past half-century, and today is the ninth most common neoplasm in the United States (US). While
S. Padala, Adam Barsouk, K. Thandra, Kalyan Saginala, A. Mohammed, Anusha Vakiti, Prashanth Rawla, Alexander Barsouk   +7 more
semanticscholar   +1 more source

Accuracy of magnetic resonance imaging to identify pseudocapsule invasion in renal tumors [PDF]

, 2020
Purpose: To evaluate accuracy of MRI in detecting renal tumor pseudocapsule (PC) invasion and to propose a classification based on imaging of PC status in patients with renal cell carcinoma.
Altobelli, Emanuela, Angeletti, Silvia, Bellangino, Mariangela, Catalano, Carlo, Ciccozzi, Massimo, Del Monte, Maurizio, D’ovidio, Giulia, Faiella Eliodoro, Gallucci, Michele, Grasso, Francesco Rosario, Mastroianni, Riccardo, Muto, Giovanni, Panebianco, Valeria, Papalia, Rocco, Scarpa, Roberto Mario, Simone, Giuseppe   +15 more
core   +1 more source

Conditional survival and long‐term efficacy with nivolumab plus ipilimumab versus sunitinib in patients with advanced renal cell carcinoma

Cancer, 2022
Conditional survival estimates provide critical prognostic information for patients with advanced renal cell carcinoma (aRCC). Efficacy, safety, and conditional survival outcomes were assessed in CheckMate 214 (ClinicalTrials.gov identifier NCT02231749 ...
R. Motzer, D. McDermott, B. Escudier, M. Burotto, T. Choueiri, H. Hammers, P. Barthélémy, E. Plimack, C. Porta, S. George, T. Powles, F. Donskov, H. Gurney, C. Kollmannsberger, M. Grimm, C. Barrios, Y. Tomita, D. Castellano, V. Grünwald, B. Rini, M. McHenry, Chung-Wei Lee, Jennifer McCarthy, F. Ejzykowicz, N. Tannir   +24 more
semanticscholar   +1 more source

Atraumatic Ruptured Giant Renal Tumor

The Annals of African Surgery, 2020
Massive hemoperitoneum due to spontaneous rupture of renal cell carcinoma is a rare presentation during emergency laparotomy. A 60-year-old female patient presented with severe abdominal pain, nausea, vomiting and abdominal distension.
Gezahen Negusse Ayane, Khutsafalo Kadimo
doaj  

The long noncoding RNA urothelial carcinoma-associated 1 overexpression as a poor prognostic biomarker in clear cell renal cell carcinoma

Tumor Biology, 2017
Long noncoding RNA urothelial carcinoma-associated 1 has previously played important roles in cancer. However, its role is still unknown in clear cell renal cell carcinoma.
Yang Wang, Wen Gao, Jiali Xu, Yizhi Zhu, Lingxiang Liu   +4 more
doaj   +1 more source

The ambitious role of anti angiogenesis molecules: Turning a cold tumor into a hot one [PDF]

, 2018
In renal cancer emerging treatment options are becoming available and there is a strong need to combine therapies to reformulate and adjourn clinical practice.
Botticelli, A., Marchetti, P., Nuti, M., Rughetti, A., Zizzari, I. G.   +4 more
core   +1 more source

Renal cell carcinoma

BMJ, 2014
The treatment of renal cell carcinoma (RCC) has changed greatly over the past 15 years. Progress in the surgical management of the primary tumor and increased understanding of the molecular biology and genomics of the disease have led to the development of new therapeutic agents.
Jonasch, Eric, Gao, Jianjun, Rathmell, W Kimryn   +2 more
openaire   +3 more sources