Results 91 to 100 of about 2,274 (220)
Synthesis of Analogues of (+)-Gomphoside, a Potent HIF-1 Inhibitor and Cardenolide
Natural Product Communications, 2018 The milkweed bush Gomphocarpus fruticosus R.Br. found in Australia contains the steroidal glycoside (+)-gomphoside, its derivatives (-)-3'-dehydrogomphoside and (+)-3'- epi -gomphoside, as well as other glycoside compounds. The key structural features of
Eckehard Cuny
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The Qualitative Identification of Cardenolide-Containing Plants Using Ultra High Performance Liquid Chromatography – High Resolution Mass Spectrometry Chromatograms at Select Ions [PDF]
, 2023 Cardiac glycosides (CGs), classified as cardenolides or bufadienolides, are toxins found in a variety of flora and fauna. CGs have historically been used to treat heart failure, but despite their place in medicine, they are still toxic to humans and ...
Ng, Megan
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12β,14-Dihydroxy-3-oxo-5β,20(22)-cardenolide monohydrate
Acta Crystallographica Section E, 2010 The title compound, digoxigenone, C23H30O5·H2O, was biotransformed from digoxigenin. In the crystal, intermolecular O—H...O hydrogen bonds contribute to the formation of a three-dimensional supramolecular structure.
Chao-Jun He +4 more
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Nucleolus and c-Myc: potential targets of cardenolide-mediated antitumor activity. [PDF]
, 2008 The use of cardenolides like ouabain, digitoxin, or oleandrin has been reported previously many times as a means of potentially combating human refractory prostate cancer by inducing apoptosis through an increase in intracellular calcium concentrations ...
Mijatovic, Tatjana +9 more
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Total Synthesis of Cardenolides Acospectoside A and Acovenoside B
MoleculesAcospectoside A (1) and acovenoside B (2), two cytotoxic cardenolides extracted from the venomous South African bush Acokanthera oppositifolia, are distinguished by their unique structural motifs of the l-acovenose moiety at C-3 and a 1β-O-acetylated ...
Benzhang Liu, Peng Xu, Biao Yu
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, 2017 Substitutions within the cardenolide target site of several insects' Na,K-ATPase α-subunits may confer resistance against toxic cardenolides. However, to which extent these substitutions alter the Na,K-ATPase's kinetic properties and how they interact ...
Dalla, Safaa +5 more
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, 1988 The composition of the defence secretions of six species of chrysomelid beetles (Chrysolina polita, C. americana, C. grossa, C. herbacea, C. fastuosa, and Oreina gloriosa) belonging to the sub‐tribe Chrysolinina has been investigated.
Van Oycke, S. +4 more
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, 2013 iv, 25 p.Plants produce an array of secondary defense compounds to combat herbivory. However, secondary compounds in nectar seem to serve a paradoxical function, since nectar is commonly used to attract insect pollinators.
Liu, Conrad K.
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PLoS ONE, 2014 Cardiotonic steroids are used to treat heart failure and arrhythmia and have promising anticancer effects. The prototypic cardiotonic steroid ouabain may also be a hormone that modulates epithelial cell adhesion. Cardiotonic steroids consist of a steroid
Sayonarah C Rocha +23 more
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The Evolution of Cardenolide-Resistant Forms of Na +,K +-Atpase in Danainae Butterflies
, 2012 Cardenolides are a class of plant secondary compounds that inhibit the proper functioning of the Na +, K +-ATPase enzyme in susceptible animals. Nonetheless, many insect species are able to sequester cardenolides for their own defence.
Zhen, Ying +2 more
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