Results 81 to 90 of about 2,590 (216)
BMC Evolutionary Biology, 2017 Background The Na,K-ATPase is a vital animal cell-membrane protein that maintains the cell’s resting potential, among other functions. Cardenolides, a group of potent plant toxins, bind to and inhibit this pump.
Jennifer N. Lohr +4 more
doaj +1 more source
Complex engineering of Solanum alkaloids structural diversity in Nicotiana benthamiana
Plant Biotechnology Journal, Volume 24, Issue 1, Page 328-345, January 2026.Summary Transient expression in Nicotiana benthamiana offers a powerful and versatile platform for rapid production of complex specialized metabolites. Steroidal glycoalkaloids (SGAs) and steroidal saponins produced by members of the Solanaceae family are known for their diverse structures and activities including antimicrobial, anticancer, antiviral ...
Sachin A. Gharat +6 more
wiley +1 more source
Cardenolide Glycosides from Elaeodendron australe var. integrifolium
, 2014 Extracts from dried leaf and stems of Elaeodendron australe var. integrifolium (Celastraceae) collected in South East Queensland, Australia, were active in an assay that measured Ca2+ driven expression of IL-2/luciferase designed to identify inhibitors ...
Hyde, Edward +10 more
core +1 more source
eLife, 2020 Phytochemical diversity is thought to result from coevolutionary cycles as specialization in herbivores imposes diversifying selection on plant chemical defenses.
Tobias Züst +16 more
doaj +1 more source
Cytotoxic cardenolide glycosides from the root of Reevesia formosana
, 2013 [[abstract]]Bioassay-guided fractionation of the root tissue of Reevesia formosana led to isolation of 13 cardenolide glycosides, reevesiosides A–I and epi-reevesiosides F–I.
Chang, HS;Chiang, MY;Hsu, HY;Yang, CW;Lin, CH;Lee, SJ;Chen, IS
core +1 more source
Toxicarioside M, a new cytotoxic 10β-hydroxy-19-nor-cardenolide from Antiaris toxicaria
, 2012 A new 10β-hydroxy-19-nor-cardenolide, named toxicarioside M (1), was isolated from the trunk bark of Antiaris toxicaria (Pers.) Lesch (Moraceae), along with six known cardenolides (convallatoxin (2), convallatoxol (3), convalloside (4), 3-O-ß-D ...
Levrier, C. +7 more
core +1 more source
Studies on growth and cardenolide production of Digitalis lanata tissue cultures
, 1989 Digitalis lanata cell cultures grown as small undifferentiated aggregates in suspension culture can be redifferentiated into green embryos that produce cardenolides.
Toivonen, Leena +4 more
core +1 more source
The Effect of Residual Roundup on Showy Milkweed Growth and Cardenolide Production [PDF]
, 2022 Western monarch butterfly populations have sharply declined over the last three decades largely due to destruction of their habitat and larval food source, milkweed (Asclepias spp.).
Silva, Estrella +3 more
core
Nucleolus and c-Myc: potential targets of cardenolide-mediated antitumor activity. [PDF]
, 2008 The use of cardenolides like ouabain, digitoxin, or oleandrin has been reported previously many times as a means of potentially combating human refractory prostate cancer by inducing apoptosis through an increase in intracellular calcium concentrations ...
Mijatovic, Tatjana +9 more
core +1 more source
, 2017 Substitutions within the cardenolide target site of several insects' Na,K-ATPase α-subunits may confer resistance against toxic cardenolides. However, to which extent these substitutions alter the Na,K-ATPase's kinetic properties and how they interact ...
Dalla, Safaa +5 more
core +1 more source