Results 171 to 180 of about 7,024 (237)

Cardenolides from Adonis aestivalis

Phytochemistry, 1992
Four cardenolides were isolated for the first time from the aerial parts of Adonis aestivalis. The compounds were identified by spectrometry and for 3-epi-periplogenin, helveticoside also by comparison with authentic substances. Two new cardenolides were structurally elucidated: strophanthidin-3-O-beta-D-digitoxosido-alpha-L-cymarosido-be ta-D ...
B, Kopp, L, Krenn, E, Kubelka, W, Kubelka   +3 more
openaire   +2 more sources

Cardenolides from Nierembergia aristata

Journal of Natural Products, 1995
The EtOAc extract of the whole plant of the Argentinian species Nierembergia aristata showed significant cytotoxicity against eleven different cancer cell lines. In addition to several known compounds, bioassay-guided fractionation led to the isolation of three new cardenolides, 17-epi-11 alpha-hydroxy-6, 7-dehydrostrophanthidin-3-O-beta ...
R R, Gil, L Z, Lin, H B, Chai, J M, Pezzuto, G A, Cordell   +4 more
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Research Progress on Plant‐Derived Cardenolides (2010–2023)

Chemistry and Biodiversity
Cardenolides are a class of steroidal glycoside compounds that are mainly distributed in plants, have significant physiological activity in the heart, and have been used clinically for over 200 years.
Yi-jiao He, Hong Yang, Lei Zhang, Zheng Gong, Guo-Li Li, Kun Gao   +5 more
semanticscholar   +1 more source

Synthesis of cardenolide glycosides and putative biosynthetic precursors of cardenolide glycosides

Steroids, 1998
A rapid and efficient procedure for glycosylation of steroids was established using a modified Koenigs-Knorr procedure. Peracetylated beta-glycosides were synthesized by reaction of cardenolides, various pregnanes and 23-nor-5,20(22)E-choldienic acid at room temperature with the peracetylated 1-bromo derivatives of D-glucose, D-galactose, D-fucose and ...
M, Luta, A, Hensel, W, Kreis
openaire   +2 more sources

Cardenolides: Insights from chemical structure and pharmacological utility

Pharmacological Research, 2019
&NA; Cardiac glycosides (CGs) are a class of naturally occurring steroid‐like compounds, and members of this class have been in clinical use for more than 1500 years.
H. El-Seedi, S. Khalifa, Eman A Taher, M. Farag, A. Saeed, Mohamed G. Abouelenein, M. Hegazy, Diaa T. A. Youssef, S. Musharraf, Muaaz Alajlani, Jianbo Xiao, T. Efferth   +11 more
semanticscholar   +1 more source

ChemInform Abstract: PARTIAL SYNTHESES OF CARDENOLIDES AND CARDENOLIDE ANALOGS. VIII. LACTONE RING‐ALKYLATED CARDENOLIDES

Chemischer Informationsdienst, 1984
AbstractBehandeln der Cardenolide (I) mit NaH in DMF, anschließen de Zugabe der Alkylhalogenide (II) binnen fünf Minuten und Ansäuern der Ansätze liefern die Monoalkylderivate (III) als Hauptprodukte, daneben die Dialkylderivate (IV).
B. STRECKENBACH, P. FRANKE, R. HINTSCHE, H. J. PORTIUS, K. R. H. REPKE   +4 more
openaire   +1 more source

Conformational states of the pig kidney Na+/K+-ATPase differently affect bufadienolides and cardenolides: a directed structure-activity and structure-kinetics study.

Biochemical Pharmacology, 2019
There is a renewed interest in the Na+/K+-ATPase (NKA, EC 3.6.3.9) either as a target for new therapeutic uses or for understanding the putative pathophysiological role of its mammalian endogenous ligands.
Pedro Azalim, Fernando M do Monte, Mariana Manzano Rendeiro, Xiaofan Liu, G. O'Doherty, Carlos Frederico Leite Fontes, S. Leitão, L. Quintas, F. Noël   +8 more
semanticscholar   +1 more source

Two cardenolides fromCalotropis procera

Magnetic Resonance in Chemistry, 1999
Two cardiotonic glycosides were isolated from Calotropois procera; one of them (1) is a new natural product. Their structures were elucidated by extensive application of oneand two-dimensional 1H and 13C NMR spectroscopy. Copyright  1999 John Wiley & Sons, Ltd.
Atef G. Hanna, M. Hani A. Elgamal, Nagy A. M. Morsy, Helmut Duddeck, József Kovács, Gábor Tóth   +5 more
openaire   +1 more source

ChemInform Abstract: CARDENOLIDES. I. RING D CLEAVAGE OF CARDENOLIDES

Chemischer Informationsdienst, 1982
AbstractDie Einwirkung von Ozon auf die Cardadienolide (I) und nachfolgende reduktive Aufarbeitung führen überraschenderweise nicht zum Abbau des Butenolidringes, sondern nahezu ausschließlich zur D‐Ringspaltung unter Bildung der 14,1 S‐Seeocardenolide (IIa) und (IIb) bzw. (Ile).
E. COHNEN, K. WEDEMEIER, V. SINNWELL
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ChemInform Abstract: PARTIAL SYNTHESES OF CARDENOLIDES AND CARDENOLIDE ANALOGS. III. SYNTHESIS OF CARDENOLIDE‐ANALOGOUS METHYL β‐STEROIDYLCROTONATES

Chemischer Informationsdienst, 1981
AbstractDas Ausgangsprodukt für die Synthesen der Cardenolid‐Analogen (VII) bzw. (XI) ist das aus dem Iodketon (I) erhaltene (II).
F. THEIL, C. LINDIG, K. REPKE
openaire   +1 more source