Results 161 to 170 of about 7,024 (237)

Four enzymes control natural variation in the steroid core ofErysimumcardenolides

Younkin GC, Alani ML, Züst T, Jander G.
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Cytotoxic cardenolides from Calotropis gigantea.

Phytochemistry, 2021
Sixteen cardiac glycosides, including five previously undescribed compounds, were extracted and purified from whole plants of Calotropis gigantea (L.).
Yigang He, Hong-ying Yang, Peishan Huang, Weiyang Feng, K. Gao   +4 more
semanticscholar   +3 more sources

Three new cardenolides from the fruits of Cascabela thevetia (L.) Lippold and their cytotoxic activities

Natural Product Research, 2022
Phytochemical investigations on the fruits of Cascabela thevetia (L.) Lippold led to obtain three new cardenolides (1–3) and five known analogues (4–7).
J. Long, Jiajing Ouyang, Yuan Luo, Qi-jing Wu, Xiao-Tong Liao, Zhi-Le Chen, Qilin Wang, Xiao-yan Liang, Li Liu, Xueqin Yang, Xiaosan Li   +10 more
semanticscholar   +1 more source

Non-classical cardenolides from Calotropis gigantea exhibit anticancer effect as HIF-1 inhibitors.

Bioorganic chemistry (Print), 2021
Six new non-classical cardenolides (1-6), and seventeen known ones (7-23) were isolated from Calotropis gigantea. All cardenolides showed inhibitory effect on hypoxia inducible factor-1 (HIF-1) transcriptional activity with IC50 of 8.85 nM-16.69 µM ...
Zhiyuan Zheng, Zhongbo Zhou, Qiulong Zhang, Xiaobo Zhou, Ji Yang, Ming-rong Yang, Guo‐Yuan Zhu, Zhihong Jiang, Ting Li, Qian-yu Lin, Li-Ping Bai   +10 more
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Structural Analysis Revealed the Interaction of Cardenolides from Calotropis procera with Na+/K+ ATPases from Herbivores.

Protein Peptide Letters, 2021
BACKGROUND The herbivores Danaus plexippus (Lepidoptera), Oncopeltus fasciatus and Aphis nerii (Hemiptera) are specialist insects that feed on Calotropis procera (Apocynaceae) (Sodom Apple). At least 35 chemically distinct cardenolides have been reported
M. Ramos, L. B. Freitas, Emanuel A. Bezerra, F. S. Morais, J. P. Lima, P. F. Souza, C. Carvalho, C. D. Freitas   +7 more
semanticscholar   +1 more source

Calosides A-F, Cardenolides from Calotropis gigantea and Their Cytotoxic Activity.

Journal of Natural Products, 2020
Phytochemical analysis of the roots of Calotropis gigantea led to the isolation of six new cardenolide glycosides, calosides A-F (1-6), and five known cardenolides (7-11).
M. T. T. Nguyen, K. Nguyen, P. Dang, H. Nguyen, S. Awale, N. Nguyen   +5 more
semanticscholar   +1 more source

Aldimines of Cardenolides and Cardenolide-Glycosides

Chemistry of Natural Compounds, 2005
New aldimines were synthesized from the cardenolide strophantidin and cardenolide-glycosides erysimin and cymarin and included morpholine, nitrile, pyridine, furan, hydroxy- and methoxyphenyl, piperidine, and other derivatives. An effective modified method for synthesizing aldimines was proposed. 52 new compounds were synthesized. Their structures were
I. F. Makarevich, Yu. I. Gubin, R. Megges   +2 more
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Cytotoxicity of cardenolides and cardenolide glycosides from Asclepias curassavica

Bioorganic & Medicinal Chemistry Letters, 2009
A new cardenolide, 12beta,14beta-dihydroxy-3beta,19-epoxy-3alpha-methoxy-5alpha-card-20(22)-enolide (6), and a new doubly linked cardenolide glycoside, 12beta-hydroxycalotropin (13), together with eleven known compounds, coroglaucigenin (1), 12beta-hydroxycoroglaucigenin (2), calotropagenin (3), desglucouzarin (4), 6'-O-feruloyl-desglucouzarin (5 ...
Jun-Zhu, Li, Chen, Qing, Chang-Xiang, Chen, Xiao-Jiang, Hao, Hai-Yang, Liu   +4 more
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Cardenolides from Erysimum cheiranthoides

Phytochemistry, 1996
Three new cardiac glycosides were isolated along with two known cardenolides from the seeds of Erysimum cheiranthoides. The new ones were characterized by spectral methods as 16 beta-hydroxystrophanthidin (strophadogenin) 3-O-beta-glucopyranosyl-(1-->4)-beta-boiviopyranoside, strophadogenin 3-O-alpha-rhamnopyranosyl-(1-->4)-beta-digitoxopyranoside and ...
Z H, Lei, S, Yahara, T, Nohara, T B, Shan, J Z, Xiong   +4 more
openaire   +2 more sources