Results 11 to 20 of about 576,149 (314)

Reduced Immunity Regulator MAVS Contributes to Non-Hypertrophic Cardiac Dysfunction by Disturbing Energy Metabolism and Mitochondrial Homeostasis

Frontiers in Immunology, 2022
Cardiac dysfunction is manifested as decline of cardiac systolic function, and multiple cardiovascular diseases (CVDs) can develop cardiac insufficiency.
Qian Wang, Qian Wang, Qian Wang, Zhenzhen Sun, Zhenzhen Sun, Zhenzhen Sun, Shihan Cao, Shihan Cao, Shihan Cao, Xiuli Lin, Xiuli Lin, Xiuli Lin, Mengying Wu, Mengying Wu, Mengying Wu, Yuanyuan Li, Yuanyuan Li, Yuanyuan Li, Jie Yin, Jie Yin, Jie Yin, Wei Zhou, Wei Zhou, Wei Zhou, Songming Huang, Songming Huang, Songming Huang, Aihua Zhang, Aihua Zhang, Aihua Zhang, Yue Zhang, Yue Zhang, Yue Zhang, Weiwei Xia, Weiwei Xia, Weiwei Xia, Zhanjun Jia, Zhanjun Jia, Zhanjun Jia   +38 more
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Protocol for Isolation of Golgi Vesicles from Human and Animal Hearts by Flotation through a Discontinuous Sucrose Gradient

STAR Protocols, 2020
Summary: Detailed study of cellular organelles requires their isolation. Several protocols have been described for the isolation of the Golgi apparatus from liver tissue, but these are not suitable and not reproducible in harder tissues.
Estefanía Tarazón, Manuel Portolés, Esther Roselló-Lletí   +2 more
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Cardiac dysfunction in a cohort of biopsy proven nonalcoholic steatohepatitis in comparison to nonalcoholic fatty liver

Egyptian Liver Journal, 2023
Introduction NAFLD (non-alcoholic fatty liver disease) is increasing worldwide. Inflammation, fibrosis, and steatosis are the three components of NAFLD. Cardiac events are the most common cause of death in NAFLD.
Jijo Varghese, Krishnadas Devadas, Neeraj Vinayakumar, Nibin Nahaz, Atul Hareendran, Tharun Tom Oommen, Bony George   +6 more
doaj   +1 more source

Il12a Deletion Aggravates Sepsis-Induced Cardiac Dysfunction by Regulating Macrophage Polarization

Frontiers in Pharmacology, 2021
Cardiac dysfunction is a well-recognized complication of sepsis and is associated with the outcome and prognosis of septic patients. Evidence suggests that Il12a participates in the regulation of various cardiovascular diseases, including heart failure ...
Zhen Wang, Zhen Wang, Zhen Wang, Menglin Liu, Di Ye, Di Ye, Di Ye, Jing Ye, Jing Ye, Jing Ye, Menglong Wang, Menglong Wang, Menglong Wang, Jianfang Liu, Jianfang Liu, Jianfang Liu, Yao Xu, Yao Xu, Yao Xu, Jishou Zhang, Jishou Zhang, Jishou Zhang, Mengmeng Zhao, Mengmeng Zhao, Mengmeng Zhao, Yongqi Feng, Yongqi Feng, Yongqi Feng, Shuwan Xu, Shuwan Xu, Shuwan Xu, Wei Pan, Wei Pan, Wei Pan, Zhen Luo, Zhen Luo, Zhen Luo, Dan Li, Jun Wan, Jun Wan, Jun Wan   +40 more
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Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

PLoS Pathogens, 2023
Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance.
Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram   +12 more
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An Update on Intradialytic Cardiac Dysfunction [PDF]

Seminars in Dialysis, 2016
AbstractCardiac dysfunction is a key factor in the high morbidity and mortality rates seen in hemodialysis (HD) patients. Much of the dysfunction is manifest as adverse changes in cardiac and vascular structure prior to commencing dialysis. This adverse vascular remodeling arises as a dysregulation between pro‐ and antiproliferative signaling pathways ...
Odudu, Aghoghomeore, McIntyre, Christopher W   +1 more
openaire   +3 more sources

Combination therapy using tafamidis and neurohormonal blockers for cardiac amyloidosis and a reduced ejection fraction: a case report

Journal of International Medical Research, 2022
Cardiac amyloidosis usually presents with diastolic dysfunction, but sometimes systolic dysfunction develops, particularly at its advanced stage. However, the therapeutic strategy for patients with cardiac amyloidosis and systolic dysfunction remains ...
Teruhiko Imamura, Toshihide Izumida, Masakazu Hori, Shuhei Tanaka, Koichiro Kinugawa   +4 more
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Origins of cardiac dysfunction in cirrhosis [PDF]

Gut, 2003
Is cirrhotic cardiomyopathy a specific cardiac dysfunction of cirrhotic patients or is it induced by the hyperdynamic circulation in these patients? The clinical course of patients with advanced liver disease is complicated by progressive impairment in circulatory function characterised by low arterial pressure, high cardiac output, and decreased ...
W, Jiménez, V, Arroyo
openaire   +2 more sources

Assessment of cardiac function in rat endovascular perforation model of subarachnoid hemorrhage; A model of subarachnoid hemorrhage-induced cardiac dysfunction

Frontiers in Synaptic Neuroscience, 2022
Although the association between cardiac dysfunction and subarachnoid hemorrhage (SAH) has been recognized, its precise underlying mechanism remains unknown. Furthermore, no suitable animal models are available to study this association.
Masahito Munakata, Hideaki Kanazawa, Kensuke Kimura, Takahide Arai, Hiroaki Sukegawa, Keiichi Fukuda   +5 more
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Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential. [PDF]

PLoS ONE, 2013
It has been recognized that changes in mitochondrial structure plays a key role in development of cardiac dysfunction, and autophagy has been shown to exert maintenance of mitochondrial homeostasis effects.
Li Wang, Keyi Lu, Haihu Hao, Xiaoyu Li, Jie Wang, Ke Wang, Jin Wang, Zi Yan, Suli Zhang, Yunhui Du, Huirong Liu   +10 more
doaj   +1 more source