Results 11 to 20 of about 1,793,619 (305)

Mitochondrial Dysfunction in Cardiac Arrhythmias

Cells, 2023
Electrophysiological and structural disruptions in cardiac arrhythmias are closely related to mitochondrial dysfunction. Mitochondria are an organelle generating ATP, thereby satisfying the energy demand of the incessant electrical activity in the heart.
Jielin Deng, Yunqiu Jiang, Zhen Bouman Chen, June-Wha Rhee, Yingfeng Deng, Zhao V. Wang   +5 more
doaj   +4 more sources

Diabetes-Related Cardiac Dysfunction [PDF]

Endocrinology and Metabolism, 2017
The proposal that diabetes plays a role in the development of heart failure is supported by the increased risk associated with this disease, even after correcting for all other known risk factors.
Lamario J. Williams, Brenna G. Nye, Adam R. Wende   +2 more
doaj   +3 more sources

An Update on Intradialytic Cardiac Dysfunction [PDF]

Seminars in Dialysis, 2016
AbstractCardiac dysfunction is a key factor in the high morbidity and mortality rates seen in hemodialysis (HD) patients. Much of the dysfunction is manifest as adverse changes in cardiac and vascular structure prior to commencing dialysis. This adverse vascular remodeling arises as a dysregulation between pro‐ and antiproliferative signaling pathways ...
Odudu, Aghoghomeore, McIntyre, Christopher W   +1 more
openaire   +5 more sources

The role of cardiac dysfunction in multiorgan dysfunction

Current Opinion in Anaesthesiology, 2016
The aim of this review was to examine the main determinants of cardiac dysfunction in critically ill patients, as well as how a reduction in cardiac performance influences other organ function.Cardiac dysfunction is a frequent complication in critically ill patients and contributes to organ hypoperfusion and poor outcome.
Abele, Donati, Andrea, Carsetti, Elisa, Damiani   +2 more
openaire   +3 more sources

Cardiac biomarkers for screening and prognostication of cardiac dysfunction in critically ill patients

ESC Heart Failure
Aims This study aimed to assess the use of high‐sensitivity troponin T (hsTNT) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) in screening for cardiac dysfunction [left ventricular (LV) systolic or diastolic dysfunction or right ventricular (RV)
Oscar Cavefors, Freyr Einarsson, Jakob Holmqvist, Odd Bech‐Hanssen, Sven‐Erik Ricksten, Björn Redfors, Jonatan Oras   +6 more
doaj   +2 more sources

Radiation-induced cardiac dysfunction: Practical implications [PDF]

, 2022
Radiation-induced cardiac dysfunction is a critical healthcare concern facing survivors of thoracic cancers treated with radiation therapy. Despite cardiac-sparing advances in radiation therapy delivery, many patients with thoracic cancers receiving ...
Schiffer, Walter; Division of Cardiology, Department of Medicine, Washington University in St. Louis, St. Louis, MO, United States, Pedersen, Lauren N; Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States, Mitchell, Joshua D; Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States; Alvin J Siteman Center, Washington University in St. Louis, St. Louis, MO, United States; Cardio-Oncology Center of Excellence, Washington University in St. Louis, St. Louis, MO, United States, Bergom, Carmen; Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States; Alvin J Siteman Center, Washington University in St. Louis, St. Louis, MO, United States; Cardio-Oncology Center of Excellence, Washington University in St. Louis, St. Louis, MO, United States, Carmen Bergom, Lauren N Pedersen, Joshua D Mitchell, Walter Schiffer   +7 more
core   +1 more source

Proteotoxicity and Cardiac Dysfunction [PDF]

Circulation Research, 2015
Baseline physiological function of the mammalian heart is under the constant threat of environmental or intrinsic pathological insults. Cardiomyocyte proteins are thus subject to unremitting pressure to function optimally, and this depends on them assuming and maintaining proper conformation.
Patrick M, McLendon, Jeffrey, Robbins
openaire   +2 more sources

Il12a Deletion Aggravates Sepsis-Induced Cardiac Dysfunction by Regulating Macrophage Polarization

Frontiers in Pharmacology, 2021
Cardiac dysfunction is a well-recognized complication of sepsis and is associated with the outcome and prognosis of septic patients. Evidence suggests that Il12a participates in the regulation of various cardiovascular diseases, including heart failure ...
Zhen Wang, Zhen Wang, Zhen Wang, Menglin Liu, Di Ye, Di Ye, Di Ye, Jing Ye, Jing Ye, Jing Ye, Menglong Wang, Menglong Wang, Menglong Wang, Jianfang Liu, Jianfang Liu, Jianfang Liu, Yao Xu, Yao Xu, Yao Xu, Jishou Zhang, Jishou Zhang, Jishou Zhang, Mengmeng Zhao, Mengmeng Zhao, Mengmeng Zhao, Yongqi Feng, Yongqi Feng, Yongqi Feng, Shuwan Xu, Shuwan Xu, Shuwan Xu, Wei Pan, Wei Pan, Wei Pan, Zhen Luo, Zhen Luo, Zhen Luo, Dan Li, Jun Wan, Jun Wan, Jun Wan   +40 more
doaj   +1 more source

Pseudomonas aeruginosa pulmonary infection results in S100A8/A9-dependent cardiac dysfunction.

PLoS Pathogens, 2023
Pseudomonas aeruginosa (P.a.) infection accounts for nearly 20% of all cases of hospital acquired pneumonia with mortality rates >30%. P.a. infection induces a robust inflammatory response, which ideally enhances bacterial clearance.
Naresh Kumar, Matthew J Pestrak, Qian Wu, Omar Santiagonunez Ahumada, Sheri Dellos-Nolan, Noushin Saljoughian, Rajni Kant Shukla, Cortney F Mitchem, Prabhakara R Nagareddy, Latha P Ganesan, Lafuse P William, Daniel J Wozniak, Murugesan V S Rajaram   +12 more
doaj   +1 more source

Combination therapy using tafamidis and neurohormonal blockers for cardiac amyloidosis and a reduced ejection fraction: a case report

Journal of International Medical Research, 2022
Cardiac amyloidosis usually presents with diastolic dysfunction, but sometimes systolic dysfunction develops, particularly at its advanced stage. However, the therapeutic strategy for patients with cardiac amyloidosis and systolic dysfunction remains ...
Teruhiko Imamura, Toshihide Izumida, Masakazu Hori, Shuhei Tanaka, Koichiro Kinugawa   +4 more
doaj   +1 more source