The relationship of myocardial and liver T2* values with cardiac function and laboratory findings in transfusion-dependent thalassemia major patients: A retrospective cardiac MRI study [PDF]
Journal of Cardiovascular and Thoracic Research, 2023 Introduction: Cardiac complications are the leading cause of death in thalassemia patients. It is assumed that progressive iron accumulation results in myocyte damage. Myocardial T2* measurement by cardiac MRI quantifies iron overload.
Sepideh Abdi +6 more
doaj +1 more source
Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively : a case control study [PDF]
, 2012 Introduction: Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP ...
Tuli, Sagun +24 more
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ESC Heart Failure, 2020 Aims Obesity doubles the lifetime risk of developing heart failure. Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient for optimal risk stratification.
Sanne M. Snelder +9 more
doaj +1 more source
The utility of B-type natriuretic peptide in predicting postoperative cardiac events and mortality in patients undergoing major emergency non-cardiac surgery [PDF]
, 2007 B-type natriuretic peptide (BNP) levels predict cardiovascular risk in several settings. We hypothesized that they would identify individuals at increased risk of complications and mortality following major emergency non-cardiac surgery.Forty patients ...
Croal, Bernard L. +4 more
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Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection
Scientific Reports, 2019 Accumulating evidence has confirmed that the expression of sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) is downregulated in heart failure and cardiac allograft rejection.
Estefanía Tarazón +9 more
doaj +1 more source
JMIR Research Protocols, 2020 BackgroundCardiovascular disease is the leading nonmalignant cause of late deaths in childhood cancer survivors. Cardiovascular disease and cardiac dysfunction can remain asymptomatic for many years, but eventually lead to progressive disease with high ...
Schindera, Christina +8 more
doaj +1 more source
Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency. [PDF]
PLoS ONE, 2014 Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better than
Jianmin Chen +5 more
doaj +1 more source
Radiation-induced cardiac dysfunction: Practical implications
, 2022 Radiation-induced cardiac dysfunction is a critical healthcare concern facing survivors of thoracic cancers treated with radiation therapy. Despite cardiac-sparing advances in radiation therapy delivery, many patients with thoracic cancers receiving ...
Bergom, Carmen; Department of Radiation Oncology, Washington University in St. Louis, St. Louis, MO, United States; Alvin J Siteman Center, Washington University in St. Louis, St. Louis, MO, United States; Cardio-Oncology Center of Excellence, Washington University in St. Louis, St. Louis, MO, United States +3 more
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Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice.
PLoS ONE, 2022 BackgroundSuppression of cardiac iinflammasome, which can be inhibited by Farnesoid X receptor (FXR) agonist, can ameliorate cardiac inflammation and fibrosis.
Szu-Yu Liu +7 more
doaj +3 more sources
The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. [PDF]
PLoS ONE, 2017 Cardiac glycosides such as digoxin are Na+/K+-ATPase inhibitors that are widely used for the treatment of chronic heart failure and cardiac arrhythmias; however, recent epidemiological studies have suggested a relationship between digoxin treatment and ...
Motoi Kobayashi +9 more
doaj +1 more source