Although the association between cardiac dysfunction and subarachnoid hemorrhage (SAH) has been recognized, its precise underlying mechanism remains unknown. Furthermore, no suitable animal models are available to study this association.
Masahito Munakata +5 more
doaj +1 more source
Origins of cardiac dysfunction in cirrhosis [PDF]
Is cirrhotic cardiomyopathy a specific cardiac dysfunction of cirrhotic patients or is it induced by the hyperdynamic circulation in these patients? The clinical course of patients with advanced liver disease is complicated by progressive impairment in circulatory function characterised by low arterial pressure, high cardiac output, and decreased ...
W, Jiménez, V, Arroyo
openaire +2 more sources
Left ventricular dysfunction in critically ill patients [PDF]
Background: Cardiac dysfunction is common in Intensive Care Unit (ICU) patients and can contribute to multiorgan failure and death. Despite this, few studies have been performed on pathogenies, prevalence, diagnosis and impact on mortality in ...
Cavefors, Oscar +14 more
core +1 more source
BET inhibition blocks inflammation-induced cardiac dysfunction and SARS-CoV-2 infection
Cardiac injury and dysfunction occur in COVID-19 patients and increase the risk of mortality. Causes are ill defined but could be through direct cardiac infection and/or inflammation-induced dysfunction. To identify mechanisms and cardio-protective drugs,
Zhao, Wei +14 more
core +2 more sources
Maternal Cardiovascular Impairment in Pregnancies Complicated by Severe Fetal Growth Restriction [PDF]
—Fetal growth restriction and preeclampsia are both conditions of placental etiology and associated to increased risk for the long-term development of cardiovascular disease in the mother. At presentation, preeclampsia is associated with maternal global
Thilaganathan, B +3 more
core +1 more source
Cardiac troponins in intensive care [PDF]
The cardiac troponins are integral components of the myofibrillary apparatus and they regulate muscle contraction. The measurement of cardiac troponins has replaced other biomarkers for the specific detection of myocardial necrosis and for the diagnosis ...
Collinson, P.O. +3 more
core +1 more source
The relationship of myocardial and liver T2* values with cardiac function and laboratory findings in transfusion-dependent thalassemia major patients: A retrospective cardiac MRI study [PDF]
Introduction: Cardiac complications are the leading cause of death in thalassemia patients. It is assumed that progressive iron accumulation results in myocyte damage. Myocardial T2* measurement by cardiac MRI quantifies iron overload.
Sepideh Abdi +6 more
doaj +1 more source
Hypothermia and postconditioning after cardiopulmonary resuscitation reduce cardiac dysfunction by modulating inflammation, apoptosis and remodeling [PDF]
Background: Mild therapeutic hypothermia following cardiac arrest is neuroprotective, but its effect on myocardial dysfunction that is a critical issue following resuscitation is not clear.
Meybohm, Patrick +29 more
core +2 more sources
Decreased autophagy in rat heart induced by anti-β1-adrenergic receptor autoantibodies contributes to the decline in mitochondrial membrane potential. [PDF]
It has been recognized that changes in mitochondrial structure plays a key role in development of cardiac dysfunction, and autophagy has been shown to exert maintenance of mitochondrial homeostasis effects.
Li Wang +10 more
doaj +1 more source
Aims Obesity doubles the lifetime risk of developing heart failure. Current knowledge on the role of obesity in causing cardiac dysfunction is insufficient for optimal risk stratification.
Sanne M. Snelder +9 more
doaj +1 more source

