The utility of B-type natriuretic peptide in predicting postoperative cardiac events and mortality in patients undergoing major emergency non-cardiac surgery [PDF]
, 2007 B-type natriuretic peptide (BNP) levels predict cardiovascular risk in several settings. We hypothesized that they would identify individuals at increased risk of complications and mortality following major emergency non-cardiac surgery.Forty patients ...
Croal, Bernard L. +4 more
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Circulating Sphingosine-1-Phosphate as A Non-Invasive Biomarker of Heart Transplant Rejection
Scientific Reports, 2019 Accumulating evidence has confirmed that the expression of sarcoplasmic reticulum calcium ATPase 2a (SERCA2a) is downregulated in heart failure and cardiac allograft rejection.
Estefanía Tarazón +9 more
doaj +1 more source
Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]
, 2014 BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Collinson, PO +5 more
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JMIR Research Protocols, 2020 BackgroundCardiovascular disease is the leading nonmalignant cause of late deaths in childhood cancer survivors. Cardiovascular disease and cardiac dysfunction can remain asymptomatic for many years, but eventually lead to progressive disease with high ...
Schindera, Christina +8 more
doaj +1 more source
Gender dimorphism of the cardiac dysfunction in murine sepsis: signalling mechanisms and age-dependency. [PDF]
PLoS ONE, 2014 Development of cardiac dysfunction is associated with increased morbidity and mortality in patients with sepsis. Increasing evidence shows that gender determines the degree of inflammatory response of the host and that females tolerate sepsis better than
Jianmin Chen +5 more
doaj +1 more source
The effects of a supervised cardiac rehabilitation exercise programme on left ventricular function in patients with ischaemic heart disease (interim report) [PDF]
, 2006 Purpose. This study sought to determine the effects of a supervised cardiac rehabilitation exercise programme on left ventricular function in patients with ischaemic heart disease and any degree of left ventricular systolic dysfunction. Subjects.
Smith, Geoffrey T.
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Obeticholic acid treatment ameliorates the cardiac dysfunction in NASH mice.
PLoS ONE, 2022 BackgroundSuppression of cardiac iinflammasome, which can be inhibited by Farnesoid X receptor (FXR) agonist, can ameliorate cardiac inflammation and fibrosis.
Szu-Yu Liu +7 more
doaj +3 more sources
The cardiac glycoside ouabain activates NLRP3 inflammasomes and promotes cardiac inflammation and dysfunction. [PDF]
PLoS ONE, 2017 Cardiac glycosides such as digoxin are Na+/K+-ATPase inhibitors that are widely used for the treatment of chronic heart failure and cardiac arrhythmias; however, recent epidemiological studies have suggested a relationship between digoxin treatment and ...
Motoi Kobayashi +9 more
doaj +1 more source
Biomedicines, 2021 The CR6-interacting factor1 (CRIF1) mitochondrial protein is indispensable for peptide synthesis and oxidative phosphorylation. Cardiomyocyte-specific deletion of CRIF1 showed impaired mitochondrial function and cardiomyopathy.
Shuyu Piao +7 more
doaj +1 more source
PLoS ONE, 2023 Speckle tracking echocardiography (STE) has been utilized to evaluate independent spatial alterations in the diabetic heart, but the progressive manifestation of regional and segmental cardiac dysfunction in the type 2 diabetic (T2DM) heart remains ...
Andrya J Durr +7 more
doaj +1 more source