Results 211 to 220 of about 182,384 (307)

TWEAK/Fn14 signaling drives oxidative cardiac injury in systemic lupus erythematosus: Evidence from patient biomarker studies, lupus mouse models, and cardiomyocyte assays

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/Fn14 signaling in SLE‐related cardiomyopathy and its potential as a ...
Yale Liu   +12 more
wiley   +1 more source

Refsum disease [PDF]

open access: yes, 2015
Leroy, Bart   +2 more
core  

Comparison of JB4 plastic resin and standard paraffin methods on student performance and student perspectives in digital histology education: A randomized controlled study

open access: yesAnatomical Sciences Education, EarlyView.
Abstract This randomized controlled study compared the effectiveness of histological preparations embedded in glycol methacrylate‐based JB4 plastic resin with traditional paraffin blocks in digital histology education. A total of 297 second‐year medical students at Sivas Cumhuriyet University participated.
Zeynep Deniz Şahin İnan   +1 more
wiley   +1 more source

Cirrhosis Promotes Cardiac Fibrosis Development by Inhibiting Notch1 in Cardiac Fibroblasts. [PDF]

open access: yesJACC Basic Transl Sci
Sun H   +13 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay   +5 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

Proteome Alterations in Cardiac Fibroblasts: Insights from Experimental Myocardial Infarction and Clinical Ischaemic Cardiomyopathy. [PDF]

open access: yesInt J Mol Sci
Russell-Hallinan A   +9 more
europepmc   +1 more source

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