Results 251 to 260 of about 182,384 (307)

Development of adeno-associated viral vectors targeting cardiac fibroblasts for efficient in vivo cardiac reprogramming. [PDF]

Stem Cell Reports
Nakano K, Sadahiro T, Fujita R, Isomi M, Abe Y, Yamada Y, Akiyama T, Honda S, French BA, Mizukami H, Ieda M.   +10 more
europepmc   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

Food Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra, Monika Bhadauria, Satendra Kumar Nirala   +2 more
wiley   +1 more source

Branched-chain amino acids deficiency promotes diabetic cardiomyopathy by activating autophagy of cardiac fibroblasts. [PDF]

Theranostics
Zhou ZY, Song K, Liu ZY, Ke YF, Shi Y, Cai K, Zhao R, Sun X, Tao H, Zhao JY.   +9 more
europepmc   +1 more source

Isorhamnetin Alleviates Renal Fibrosis Induced by Renal Tubular Epithelial Cell Senescence Via Inhibition of the IL‐6/IL‐6R Signaling Pathway

iMetaMed, EarlyView.
IL‐6 from RTECs upregulates TGF‐β in macrophages, promoting fibroblast transdifferentiation. Isorhamnetin inhibits this effect. ABSTRACT Chronic kidney disease (CKD) is a major global health issue. Kidney fibrosis is a key mechanism leading to end‐stage renal disease.
Weifei Liang, Xiangqiu Chen, Tao Wu, Xichun Zheng, Shaohua Zeng, Qingchun Zhou, Wen Ma, Hao Lin, Donglin Sun   +8 more
wiley   +1 more source

Novel Identification of Ankyrin-R in Cardiac Fibroblasts and a Potential Role in Heart Failure. [PDF]

Int J Mol Sci
Argall AD, Sucharski-Argall HC, Comisford LG, Jurs SJ, Seminetta JT, Wallace MJ, Crawford CA, Takenaka SS, Han M, El Refaey M, Hund TJ, Mohler PJ, Koenig SN.   +12 more
europepmc   +1 more source

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, EarlyView.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

CD63 as novel target for nanoemulsion-based ¹⁹F MRI imaging and drug delivery to activated cardiac fibroblasts. [PDF]

Theranostics
Euan Martínez AA, Bergmann AK, Tellkamp F, Schott-Verdugo S, Bouvain P, Steinhausen J, Bahr J, Kmietczyk V, Bencun M, Flögel U, Distler JHW, Krueger M, Völkers M, Czekelius C, Gohlke H, Temme S, Hesse J, Schrader J.   +17 more
europepmc   +1 more source

CDX1 improves nicotine induced cardiac fibroblasts activation and cardiomyocyte hypertrophy by alleviating autophagic flux impairment through modulation of LAPTM4B. [PDF]

Sci Rep
Li YY, Meng FL, Zhou SY, Du JM, Li WJ, Liu QY, Wu L, Zhao MM, Jin Y, Zhang QY, Li Y, Su GH.   +11 more
europepmc   +1 more source

The dual endothelin-1 antagonist aprocitentan alleviates mitochondrial oxidative stress in human cardiac fibroblasts. [PDF]

Eur Heart J Cardiovasc Pharmacother
Varzideh F, Jankauskas SS, Jain U, Soderquist L, Densu Agyapong E, Kansakar U, Santulli G.   +6 more
europepmc   +1 more source

WISP-1 Regulates Cardiac Fibrosis by Promoting Cardiac Fibroblasts' Activation and Collagen Processing. [PDF]

Cells
Li Z, Williams H, Jackson ML, Johnson JL, George SJ.   +4 more
europepmc   +1 more source