Results 261 to 270 of about 182,384 (307)

Regulation of cardiac fibroblasts reprogramming into cardiomyocyte-like cells with a cocktail of small molecule compounds. [PDF]

FEBS Open Bio
Chang D, Sun C, Tian X, Liu H, Jia Y, Guo Z.   +5 more
europepmc   +1 more source

Atrial cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 727-729, April 2025.
Wojciech Kosmala, Monika Przewłocka‐Kosmala   +1 more
wiley   +1 more source

The local mechanosensitive response of primary cardiac fibroblasts is influenced by the microenvironment mechanics. [PDF]

Sci Rep
Braidotti N, Demontis G, Conti M, Andolfi L, Ciubotaru CD, Sbaizero O, Cojoc D.   +6 more
europepmc   +1 more source

BAG3 localizes to mitochondria in cardiac fibroblasts and regulates mitophagy.

Am J Physiol Heart Circ Physiol
Martin TG, Sherer LA, Kirk JA.
europepmc   +1 more source

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Antigen presentation by cardiac fibroblasts promotes cardiac dysfunction

Nature Cardiovascular Research, 2022
Heart failure (HF) is a leading cause of morbidity and mortality. Studies in animal models and patients with HF revealed a prominent role for CD4+ T cell immune responses in the pathogenesis of HF and highlighted an active crosstalk between cardiac fibroblasts and IFNγ producing CD4+ T cells that results in profibrotic myofibroblast transformation ...
Njabulo Ngwenyama, Kuljeet Kaur, Darrian Bugg, Brandon Theall, Mark Aronovitz, Robert Berland, Smaro Panagiotidou, Caroline Genco, Mercio A. Perrin, Jennifer Davis, Pilar Alcaide   +10 more
openaire   +2 more sources

Cardiac Fibroblast Diversity

Annual Review of Physiology, 2020
Cardiac fibrosis is a pathological condition that occurs after injury and during aging. Currently, there are limited means to effectively reduce or reverse fibrosis. Key to identifying methods for curbing excess deposition of extracellular matrix is a better understanding of the cardiac fibroblast, the cell responsible for collagen production.
openaire   +2 more sources

The heart of cardiac reprogramming: The cardiac fibroblasts

Journal of Molecular and Cellular Cardiology, 2022
Cardiovascular disease is the leading cause of death worldwide, outpacing pulmonary disease, infectious disease, and all forms of cancer. Myocardial infarction (MI) dominates cardiovascular disease, contributing to four out of five cardiovascular related deaths.
Shea N, Ricketts, Li, Qian
openaire   +2 more sources

Intracellular Signaling of Cardiac Fibroblasts

Comprehensive Physiology, 2015
ABSTRACTLong regarded as a mere accessory cell for the cardiomyocyte, the cardiac fibroblast is now recognized as a critical determinant of cardiac function in health and disease. A recent renaissance in fibroblast‐centered research has fostered a better understanding than ever before of the biology of fibroblasts and their contractile counterparts ...
Patricia L, Roche, Krista L, Filomeno, Rushita A, Bagchi, Michael P, Czubryt   +3 more
openaire   +2 more sources

Basic Signaling in Cardiac Fibroblasts

Journal of Cellular Physiology, 2016
Cardiac fibroblasts are commonly known as supporting cells of the cardiac network and exert many essential functions that are fundamental for normal cardiac growth as well as for cardiac remodeling process during pathological conditions. This review focuses on the roles of cardiac fibroblasts in the formation and regulation of the extracellular matrix ...
Stéphanie, Chacar, Nassim, Farès, Patrick, Bois, Jean-François, Faivre   +3 more
openaire   +2 more sources

Cardiac Fibroblast Physiology and Pathology

Comprehensive Physiology, 2015
ABSTRACTCardiac function is mediated by interactions between the cellular constituents of the heart, as well as the extracellular matrix. The major cell types of the heart include cardiac fibroblasts, myocytes, endothelial cells, and vascular smooth muscle cells.
David, Dostal, Shannon, Glaser, Troy A, Baudino   +2 more
openaire   +2 more sources