Cardiac glycoside ouabain efficiently targets leukemic stem cell apoptotic machinery independent of cell differentiation status. [PDF]
Cell Commun Signal, 2023 Poohadsuan J +6 more
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Cardiac Glycoside Oleandrin Suppresses EMT Ability in Endometrial Carcinoma Cells. [PDF]
Int J Mol Cell Med, 2023 Secer Celik F, Eroglu Gunes C, Kurar E.
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Transcriptome Profiling of Cardiac Glycoside Treatment Reveals EGR1 and Downstream Proteins of MAPK/ERK Signaling Pathway in Human Breast Cancer Cells. [PDF]
Int J Mol Sci, 2023 Pavithran H, Kumavath R, Ghosh P.
europepmc +1 more source
Genome and Tissue‐Specific Transcriptome of the Tropical Milkweed (Asclepias curassavica)
Plant DirectTropical milkweed (Asclepias curassavica) serves as a host plant for monarch butterflies (Danaus plexippus) and other insect herbivores that can tolerate the abundant cardiac glycosides that are characteristic of this species.
Honglin Feng +9 more
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Pharmacology of Antiarrhythmics: Quinidine, Beta-Blockers, Diphenylhydantoin, Bretylium [PDF]
, 1973 The electrophysiologic effects of the antiarrhythmic drugs, presented elsewhere in this symposium, form only one of the bases for the selection of a therapeutic agent in any given clinical situation.
Proctor, Jack D., Wasserman, Albert J.
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Convergent evolution of cardiac-glycoside resistance in predators and parasites of milkweed herbivores. [PDF]
Curr Biol, 2021 Groen SC, Whiteman NK.
europepmc +1 more source
The cardiac glycoside ZINC253504760 induces parthanatos-type cell death and G2/M arrest via downregulation of MEK1/2 phosphorylation in leukemia cells. [PDF]
Cell Biol Toxicol, 2023 Zhou M, Boulos JC, Klauck SM, Efferth T.
europepmc +1 more source
Identification of a Cardiac Glycoside Exhibiting Favorable Brain Bioavailability and Potency for Reducing Levels of the Cellular Prion Protein. [PDF]
Int J Mol Sci, 2022 Eid S +8 more
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Cardiac glycoside binding sites in cultured heart muscle cells [PDF]
, 1984 Erdmann, E. +4 more
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The Cardiac Glycosides Digitoxin, Digoxin and Ouabain Induce a Potent Inhibition of Glycolysis in Lung Cancer Cells [PDF]
, 2013 Cardiac glycosides are promising anticancer drugs. We have recently shown that the cardiac glycosides digitoxin, digoxin and ouabain induce selective killing of lung cancer cells, and that the cytotoxicity of digitoxin against these cells occurs at ...
Burgos Morón, Estefanía +2 more
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