Results 81 to 90 of about 764,918 (182)

Flavonol glycoside chemical structures

, 2022
Structures, CAS, and SMILES for 12 flavonol ...
Hadacek, Franz
core   +1 more source

Cardenolides in the defensive fluid of adult large milkweed bugs have differential potency on vertebrate and invertebrate predator Na+/K+-ATPases

Royal Society Open Science
Aposematic animals rely on diverse secondary metabolites for defence. Various hypotheses, such as competition, life history and multifunctionality, have been posited to explain defence variability and diversity.
P. Rubiano-Buitrago, S. Pradhan, A. A. Aceves, S. Mohammadi, C. Paetz, H. M. Rowland   +5 more
doaj   +1 more source

Inhibiting Na+/K+ ATPase can impair mitochondrial energetics and induce abnormal Ca2+ cycling and automaticity in guinea pig cardiomyocytes.

PLoS ONE, 2014
Cardiac glycosides have been used for the treatment of heart failure because of their capabilities of inhibiting Na+/K+ ATPase (NKA), which raises [Na+]i and attenuates Ca2+ extrusion via the Na+/Ca2+ exchanger (NCX), causing [Ca2+]i elevation.
Qince Li, Steven M Pogwizd, Sumanth D Prabhu, Lufang Zhou   +3 more
doaj   +1 more source

Adaptogenic‐Like Potential of Bauhinia forficata Leaf Extracts: Behavioral and Oxidative Outcomes in an Acute Stress Mouse Model

Brain and Behavior, Volume 16, Issue 10, October 2026.
Graphical abstract ilustrates the adaptogenic‐like potential of crude extracts (CEs) and dichloromethane (DCM) fraction from B. forficata leaves in an acute stress mouse model. C57BL/6J/UFU mice were submitted to a social isolation protocol and both CE (30 mg/kg) and DCM (10 mg/kg) significantly reduced immobility in the forced swim test and increased ...
Sofia Alencar Lafetá, Thiago Neves Vieira, Rodrigo Rodrigues Franco, Ana Claudia Gontijo Couto, Vinicius Prado Bittar, Maria Sol Peña Carrillo, Renata Roland Teixeira, André Luis Lopes Saraiva, Allisson Benatti Justino, Tamara Silva, Veridiana de Melo Rodrigues Ávila, Foued Salmen Espíndola, Cássia Regina Silva   +12 more
wiley   +1 more source

Optimization and validation of high-performance liquid chromatography method for the analysis of cardiac glycosides in Digitalis lanata

, 2009
A simple and reliable HPLC method for the qualitative and quantitative analysis of cardiac glycoside in D.
BELLARDI, MARIA GRAZIA, BERTACCINI, ASSUNTA, Pellati F., R. Bruni   +3 more
core   +1 more source

Allamanda cathartica leaves do not contain cardioactive glycosides [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Allamanda cathartica, a plant used in traditional medicine for different purposes, has been considered a cardiotoxic plant. However, the alleged cardiac glycoside was not further studied. Thus, the present study aimed to determine whether the leaves of A.
B.P. Santos, G.P.P. Ataíde, C.J.C. Saraiva, M.S. Teixeira, B. Soto-Blanco   +4 more
doaj   +1 more source

Multi‐Omics and Computational Pharmacology Approach With Experimental Validation Reveals the Antiproliferative Activity of Sophoricoside Against Pancreatic Cancer

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
An integrated pipeline combining network pharmacology, machine learning, and multi‑omics reveals that sophoricoside suppresses pancreatic cancer cell proliferation through PTPN1, a downstream effector. Elevated PTPN1 correlates with poor prognosis and immune infiltration, positioning it as a promising therapeutic node and prognostic biomarker for this ...
Peng Lin, Wei Cheng, Xin Qi, Jing Li
wiley   +1 more source

Traditional Uses, Phytochemistry, and Multi‐Target Pharmacological Activities of Senna alexandrina

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
Senna alexandrina is a medicinally important plant with documented use across Traditional Chinese, Islamic, Ayurvedic, and Unani medicine systems. Phytochemical investigations have yielded 219 characterized compounds, predominantly anthraquinones, flavonoids, and polysaccharides, distributed across leaves, pods, and aerial parts.
Diana Afrina Rella, Khai‐Lin Hew, Yeun‐Mun Choo   +2 more
wiley   +1 more source

Structural changes to Na+/K+-ATPase affecting cardiac glycoside resistance

, 2016
Cardiac glycosides are steroidal toxins comprising the cardenolides and bufadienolides that bind to the sodium-potassium pump (Na+/K+-ATPase) to inhibit ion transport and signaling.
Ding, Jamie Yan
core  

The Composition and Biochemical Properties of Strophantus (Apocynaceae), with a Focus on S. sarmentosus

Molecules
The genus Strophantus belongs to the Apocynaceae family of flowering plants which grows primarily in tropical Africa. The plants are widely used in traditional herbal medicine. S. sarmentosus, in particular, is used for the treatment of, e.g., joint pain
Simone König
doaj   +1 more source