Results 71 to 80 of about 764,918 (182)

Fatality Following Intentional Ingestion of Cerbera odollam Seeds

open access: yesClinical Practice and Cases in Emergency Medicine, 2018
Seeds from the mangrove plant Cerbera (C.) odollam, known as the “suicide tree,” are responsible for a significant number of plant deaths worldwide but are not well recognized in Western medicine. Cerberin is a cardiac glycoside concentrated in the plant’
Ryan Misek   +3 more
doaj   +1 more source

Behavioural manipulation of the cabbage stem flea beetle (Psylliodes chrysocephala L): Prospects for push–pull strategies in oilseed rape

open access: yesPest Management Science, Volume 82, Issue 11, Page 10551-10560, November 2026.
Behavioural manipulation of Psylliodes chrysocephala provides promising opportunities for sustainable pest management in oilseed rape systems. This review synthesises evidence on glucosinolates and their volatile isothiocyanate derivatives as phagostimulants and attractants, alongside the repellent or antifeedant effects of non‐host plants, plant ...
Suleiman Mustapha   +6 more
wiley   +1 more source

Cardiac Glycosides Induce Resistance to Tubulin-Dependent Anticancer Drugs in Androgen-Independent Human Prostate Cancer

open access: yes, 2009
Due to high prevalence and mortality and the lack of effective therapies, prostate cancer is one of the most crucial health problems in men. Drug resistance aggravates the situation, not only in human prostate cancer but also in other cancers.
CHUEH, SHIH-CHIEH;TENG, CHE-MING   +1 more
core  

Antagonism of the Sodium-Potassium ATPase Impairs Chikungunya Virus Infection

open access: yesmBio, 2016
Chikungunya virus (CHIKV) is a reemerging alphavirus that has caused epidemics of fever, arthralgia, and rash worldwide. There are currently no licensed vaccines or antiviral therapies available for the prevention or treatment of CHIKV disease.
Alison W. Ashbrook   +7 more
doaj   +1 more source

Histone deacetylase inhibitors as venetoclax‐sensitising partners in acute myeloid leukaemia: Mechanisms, pharmacology and translational perspectives

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 21, Page 6261-6290, November 2026.
Abstract Venetoclax combined with hypomethylating agents has improved treatment for older or unfit patients with acute myeloid leukaemia (AML), but resistance and relapse remain common. This review analyses the rationale for combining venetoclax with inhibitors of histone deacetylase (HDAC).
Jaebok Lee, Marc Diederich
wiley   +1 more source

Natural Product‐Induced Ferroptosis to Overcome Therapy Resistance in Aggressive Cancers

open access: yesChemMedChem, Volume 21, Issue 20, 28 October 2026.
Natural products trigger ferroptosis through iron overload, glutathione depletion, glutathione peroxidase 4 inhibition, and reactive oxygen species accumulation, selectively targeting aggressive, and drug‐resistant cancers. Polyphenols, alkaloids and terpenoids emerge as promising multi‐target agents to overcome therapy resistance and improve future ...
Giorgio Antoniolli
wiley   +1 more source

Identification of Carbohydrate Metabolism Genes in the Metagenome of a Marine Biofilm Community Shown to Be Dominated by Gammaproteobacteria and Bacteroidetes [PDF]

open access: yes, 2010
Polysaccharides are an important source of organic carbon in the marine environment and degradation of the insoluble and globally abundant cellulose is a major component of the marine carbon cycle.
Joint, IR   +28 more
core   +1 more source

Intoxication with Ornithogalum arabicum is a potential cause of visual impairment and irreversible blindness in dogs

open access: yesToxicon: X, 2019
We describe two dogs with persistent visual impairment after initially mild intoxication signs following ingestion of Ornithogalum arabicum plant material.
Inge J.M. Slenter   +3 more
doaj   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

open access: yesAdvanced Science, Volume 13, Issue 57, 14 October 2026.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon   +6 more
wiley   +1 more source

Cardiac troponin I but not cardiac troponin T adheres to polysulfone dialyser membranes in an in vitro haemodialysis model: explanation for lower serum cTnI concentrations following dialysis. [PDF]

open access: yes, 2014
BACKGROUND: Elevated serum cardiac troponin T (cTnT) and I (cTnI) can occur in patients with chronic kidney disease. Differences in cTn concentrations between cTnT and cTnI have been reported but the mechanism of such discrepancy has not been ...
Collinson, PO   +5 more
core   +1 more source

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