Results 51 to 60 of about 20,846 (206)

17βH-Neriifolin Improves Cardiac Remodeling Through Modulation of Calcium Handling Proteins in the Heart Failure Rat Model

open access: yesBiomedicines
Background: Cardiac glycosides such as digoxin have been commonly used for patients with heart failure; however, their toxicity remains a main concern.
Rajasegar Anamalley   +3 more
doaj   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi   +15 more
wiley   +1 more source

Synthesis and evaluation of cardiac glycoside mimics as potential anticancer drugs

open access: yes, 2011
The cardiac glycoside digitoxin, consisting of a steroid core linked to a labile trisaccharide, has been used for centuries for the treatment of congestive heart failure.
Henrik H. Jensen   +9 more
core   +1 more source

Glycoside oleandrin downregulates toll-like receptor pathway genes and associated miRNAs in human melanoma cells [PDF]

open access: yes, 2022
Melanoma accounts for the majority of skin cancer-related deaths. Nerium oleander is a plant known to be toxic and consumed due to the cardiac glycosides it contains. Oleandrin is a cardiac glycoside obtained from of N. oleander.
Çelik, Fatma Seçer   +11 more
core   +1 more source

Recent Advances in Photocatalyst‐Driven Protein Labeling and Proximity Mapping

open access: yesThe Chemical Record, EarlyView.
Photocatalyst‐driven protein labeling and proximity mapping have rapidly advanced as powerful strategies for spatiotemporal control in complex biological environments. This review integrates recent developments across single‐electron transfer and energy transfer‐based mechanisms and highlights how catalyst design, reactive intermediates, and diffusion ...
Shinichi Sato   +3 more
wiley   +1 more source

Techniques for studying the pharmacodynamic effects of cardiac glycosides on patients' own erythrocytes during glycoside therapy.

open access: yes, 1981
We have measured the effects of digoxin on the cation transport mechanisms of patients' erythrocytes during treatment with digoxin for atrial fibrillation and cardiac failure in sinus rhythm. The results show that during short-term treatment with digoxin
Ford, AR   +3 more
core   +1 more source

Systemic medications associate with surgically treated cataract among adults over 50 years in Finland

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To identify associations between systemic drugs and cataract surgery in Finland. Methods A historic cohort study based on administrative data. Endpoint event was cataract surgery. Use of drugs in question was based on redeemed prescriptions and consisted of 156 drugs.
Antti Riikonen   +3 more
wiley   +1 more source

Suspected cardiac glycoside intoxication in sheep and goats in Namibia due to Ornithogalum nanodes (Leighton) [PDF]

open access: yes, 1998
The articles have been scanned in colour with a HP Scanjet 5590; 600dpi. Adobe Acrobat X Pro was used to OCR the text and also for the merging and conversion to the final presentation PDF-format.The main clinical and necropsy features of field and ...
Bamhare, C.
core  

The connection between the cardiac glycoside‐induced senescent cell morphology and Rho/Rho kinase pathway

open access: yes, 2018
Recently drug-induced senescence has gained momentum as a new approach in cancer therapy. It is accepted that senescent cells display typical phenotypic features including flattened, enlarged, and multinucleated cell morphology.
Yaprak Dilber Şimay   +7 more
core   +1 more source

Evaluation of HSYA and Carthamin Accumulation in Safflower (Carthamus tinctorius L.) Induced by Chemical Mutagens (EMS and SA) in M1 and M2 Generations

open access: yesPlant Breeding, EarlyView.
ABSTRACT Historically cultivated for medicinal and dyeing purposes, safflower (Carthamus tinctorius L.) saw a shift towards widespread oilseed production after the 1920s due to the growing importance of oils. However, there is a renewed interest in its medicinal and dyeing properties today.
Tansu Uskutoglu   +2 more
wiley   +1 more source

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