Results 31 to 40 of about 1,567,002 (208)

The role of fluorescence polarization immuno-assay in the diagnosis of plant-induced cardiac glycoside poisoning livestock in South Africa

Onderstepoort Journal of Veterinary Research, 2005
Poisoning with cardiac glycoside-containing plants is collectively the most important plant-associated poisoning of livestock in southern Africa. As a diagnosis of this significant poisoning is currently based on circumstantial evidence, a practical ...
R.A. Schultz, T.S. Kellerman, H. Van den Berg   +2 more
doaj   +1 more source

Ca²⁺-Driven Selectivity of the Effect of the Cardiotonic Steroid Marinobufagenin on Rabbit Sinoatrial Node Function

Cells, 2023
The synergy between Na+-K+ pumps, Na+-Ca2+ exchangers, membrane currents and the sarcoplasmic reticulum (SR) generates the coupled-clock system, which governs the spontaneous electrical activity of heart sinoatrial node cells (SANCs).
Sofia Segal, Yael Yaniv
doaj   +1 more source

PHARMACOLOGICAL CORRECTION OF DILATED CARDIOMYOPATHY IN DOGS

Ветеринарная патология, 2021
In the practice of treating small domestic animals, cardiac diseases account for a signifcant part of cases of internal diseases of non-infectious etiology.
M. N. Lifentsova, E. A. Gorpinchenko, A. R. Ratnikov, K. S. Zaiko   +3 more
doaj   +1 more source

Differential accumulation of cardenolides from Asclepias curassavica by large milkweed bugs does not correspond to availability in seeds or biological activity on the bug Na+/K+-ATPase

Frontiers in Ecology and Evolution, 2023
Milkweed–herbivore systems are characterized by cardenolide chemical defenses and specialized herbivore adaptations such as physiological target site insensitivity.
Paola Rubiano-Buitrago, Paola Rubiano-Buitrago, Shrikant Pradhan, Veit Grabe, Alfonso Aceves-Aparicio, Christian Paetz, Hannah M. Rowland   +6 more
doaj   +1 more source

Cardiac Glycoside Plants Self-Poisoning

Acta Medica Bulgarica, 2014
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander, Convallaria majalis (lily of the valley), Strophanthus gratus, etc.
Radenkova-Saeva J., Atanasov P.
doaj   +1 more source

Cardiac glycoside cerberin exerts anticancer activity through PI3K/AKT/mTOR signal transduction inhibition.

Cancer Letters, 2019
Natural products possess a significant role in anticancer therapy and many currently-used anticancer drugs are of natural origin. Cerberin (CR), a cardenolide isolated from the fruit kernel of Cerbera odollam, was found to potently inhibit cancer cell ...
M. Hossan, Zi-Yang Chan, H. Collins, F. Shipton, M. Butler, M. Rahmatullah, J. Lee, P. Gershkovich, L. Kagan, T. Khoo, C. Wiart, T. Bradshaw   +11 more
semanticscholar   +1 more source

CARDIAC GLYCOSIDES IN UP-TO-DATE CLINICAL PRACTICE

Alʹmanah Kliničeskoj Mediciny, 2016
The article reviews the use of cardiac glycosides in patients with chronic heart failure, paroxysmal tachyarrhythmia and chronic atrial fibrillation (rate control).
M. A. Gurevich, A. A. Gavrilin
doaj   +1 more source

Plants containing cardiac glycosides showing antiphytoviral activity against Potato virus Y (PVYNTN) on tobacco plants

Journal of Plant Protection Research, 2018
The tuber necrotic strain of Potato virus Y (PVYNTN) causes widespread disease and has severe negative effects on the growth and yields of plants, especially those of the Solanaceae family.
Simin Emamzadeh Yazdi, Julia Mulabisana, Gerhard Prinsloo, Michele Cloete, Quenton Kritzinger   +4 more
doaj   +1 more source

Strophanthidin Attenuates MAPK, PI3K/AKT/mTOR, and Wnt/β-Catenin Signaling Pathways in Human Cancers

Frontiers in Oncology, 2020
Lung cancer is the most prevalent in cancer-related deaths, while breast carcinoma is the second most dominant cancer in women, accounting for the most number of deaths worldwide.
Dhanasekhar Reddy, Preetam Ghosh, Ranjith Kumavath   +2 more
doaj   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source