The role of fluorescence polarization immuno-assay in the diagnosis of plant-induced cardiac glycoside poisoning livestock in South Africa [PDF]
Onderstepoort Journal of Veterinary Research, 2005 Poisoning with cardiac glycoside-containing plants is collectively the most important plant-associated poisoning of livestock in southern Africa. As a diagnosis of this significant poisoning is currently based on circumstantial evidence, a practical ...
R.A. Schultz +2 more
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CARDIAC GLYCOSIDES IN UP-TO-DATE CLINICAL PRACTICE
Alʹmanah Kliničeskoj Mediciny, 2016 The article reviews the use of cardiac glycosides in patients with chronic heart failure, paroxysmal tachyarrhythmia and chronic atrial fibrillation (rate control).
M. A. Gurevich, A. A. Gavrilin
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Journal of Kerbala for Agricultural Sciences, 2022 The Explants that was used in the experiment to stimulate the production of glycoside compounds is the tips of the vegetative branches with a length of 2 cm obtained from the stage of vegetative multiplication growing from seeds treated with gamma ...
Sarab A. Almukhtar
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Retinoschisin and Cardiac Glycoside Crosstalk at the Retinal Na/K-ATPase. [PDF]
Invest Ophthalmol Vis Sci, 2020 PURPOSE. Mutations in the RS1 gene, which encodes retinoschisin, cause X-linked juvenile retinoschisis, a retinal dystrophy in males. Retinoschisin specifically interacts with the retinal sodium-potassium adenosine triphosphatase (Na/K-ATPase), a ...
Schmid V +5 more
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Convergent evolution of cardiac-glycoside resistance in predators and parasites of milkweed herbivores. [PDF]
Curr Biol, 2021 The community of plant-feeding insects (herbivores) that specialize on milkweeds (Apocynaceae) form a remarkable example of convergent evolution across levels of biological organization1.
Groen SC, Whiteman NK.
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Inflammasome inhibition blocks cardiac glycoside cell toxicity. [PDF]
J Biol Chem, 2019 Chronic heart failure and cardiac arrhythmias have high morbidity and mortality, and drugs for the prevention and management of these diseases are a large part of the pharmaceutical market.
LaRock DL +7 more
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A Fatal Case of Suicide Fruit Ingestion in Singapore by Cerbera Cardiac Glycoside Intoxication: Case Report and Review of Literature [PDF]
Asia Pacific Journal of Medical Toxicology, 2020 Case Presentation: We present a case of Cerbera fruit ingestion which highlight the knowledge gap in unusual glycoside poisoning. Despite the patient’s asymptomatic presentation, life threatening clinical features such as hyperkalaemia, hypotension and ...
Yee Shay Lee +3 more
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Enhanced genome editing in human iPSCs with CRISPR-CAS9 by co-targeting ATP1a1 [PDF]
PeerJ, 2020 Genome editing in human induced pluripotent stem cells (iPSCs) provides the potential for disease modeling and cell therapy. By generating iPSCs with specific mutations, researchers can differentiate the modified cells to their lineage of interest for ...
Jui-Tung Liu +3 more
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Pharmacological aspects of acute treatment glycoside intoxication
Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье, 2021 Despite the active introduction of surgical treatments for cardiac pathology and new synthetic cardiotonic drugs, cardiac glycosides (CG) remain an important component of the pharmacological treatment of heart diseases.
M. I. Sperling +2 more
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Molecular Modes of Action of an Aqueous Nerium oleander Extract in Cancer Cells In Vitro and In Vivo
Molecules, 2023 Cancer drug resistance remains a major obstacle in clinical oncology. As most anticancer drugs are of natural origin, we investigated the anticancer potential of a standardized cold-water leaf extract from Nerium oleander L., termed Breastin.
Luay J. Rashan +9 more
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