Results 21 to 30 of about 764,918 (182)

Activated charcoal hemadsorption in Cerbera odollam poisoning

open access: yesApollo Medicine, 2022
Cerbera odollam belongs to the poisonous Apocynaceae family, which grows in coastal salt swamps, creeks and along river banks found in South India. The poisonous part of the plant is the kernel containing the toxin cerberin which is a cardiac glycoside ...
Dyna Jones   +3 more
doaj   +1 more source

PHARMACOLOGICAL CORRECTION OF DILATED CARDIOMYOPATHY IN DOGS

open access: yesВетеринарная патология, 2021
In the practice of treating small domestic animals, cardiac diseases account for a signifcant part of cases of internal diseases of non-infectious etiology.
M. N. Lifentsova   +3 more
doaj   +1 more source

Differential accumulation of cardenolides from Asclepias curassavica by large milkweed bugs does not correspond to availability in seeds or biological activity on the bug Na+/K+-ATPase

open access: yesFrontiers in Ecology and Evolution, 2023
Milkweed–herbivore systems are characterized by cardenolide chemical defenses and specialized herbivore adaptations such as physiological target site insensitivity.
Paola Rubiano-Buitrago   +6 more
doaj   +1 more source

Ca2+-Driven Selectivity of the Effect of the Cardiotonic Steroid Marinobufagenin on Rabbit Sinoatrial Node Function

open access: yesCells, 2023
The synergy between Na+-K+ pumps, Na+-Ca2+ exchangers, membrane currents and the sarcoplasmic reticulum (SR) generates the coupled-clock system, which governs the spontaneous electrical activity of heart sinoatrial node cells (SANCs).
Sofia Segal, Yael Yaniv
doaj   +1 more source

Cardiac Glycoside Plants Self-Poisoning

open access: yesActa Medica Bulgarica, 2014
Cardiac glycosides are found in a diverse group of plants including Digitalis purpurea and Digitalis lanata (foxgloves), Nerium oleander, Convallaria majalis (lily of the valley), Strophanthus gratus, etc.
Radenkova-Saeva J., Atanasov P.
doaj   +1 more source

Erysimum cheiranthoides, an ecological research system with potential as a genetic and genomic model for studying cardiac glycoside biosynthesis [PDF]

open access: yes, 2018
At least twelve plant families contain species that synthesize cardiac glycosides as defense against herbivory. These inhibitors of animal Na+, K+-ATPases also have medical uses in treating congestive heart failure and other diseases.
Mahdieh Mirzaei   +5 more
core   +2 more sources

Complete Pathway Refactoring and Combinatorial Biosynthesis of Anthracyclines for Modulation of Histone Eviction and DNA Damage Bioactivities

open access: yesAngewandte Chemie, EarlyView.
A synthetic biology platform was established for the complete refactoring of complex anthracycline biosynthetic pathways in Streptomyces coelicolor using standardized, chemically synthetic DNA parts. This modular construction enabled streamlined combinatorial biosynthesis, yielding novel analogs that decouple DNA damage from chromatin damage (histone ...
Rongbin Wang   +15 more
wiley   +2 more sources

Extractability of Thevetia Peruviana Glycoside using Various Organic Solvents [PDF]

open access: yes, 2014
This work was designed to investigate the suitable organic solvent(s) for the effective removal of Thevetia peruviana glycoside in the seed. The anti-nutritional status of the seed was also assessed. Of all anti-nutrients screened (Tannins, Phlobatannins,
Adulsalami, Mohammed Sani   +4 more
core   +1 more source

Impaired cardiac autonomic nervous control after cardiac bypass surgery for congenital heart disease [PDF]

open access: yes, 2009
We undertook a study to describe changes in heart rate variability (HRV) postoperatively in children undergoing cardiac bypass surgery for congenital heart disease (CHD).
McGlone, Laura   +4 more
core   +4 more sources

Synthesis of an F−H Gambierol Subunit Using a C-Glycoside-Centered Strategy

open access: yes, 2016
This manuscript describes our synthesis of the F−H subunit of gambierol. In addition to the synthesis of the tricycle, of note is an interesting protecting group influence on the generation of a C(23) C-glycoside as well as the use of ring-closing ...
Jon D. Rainier (1688194)   +2 more
core   +2 more sources

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