Results 91 to 100 of about 28,908 (220)

A New Cytotoxic Pregnanone from Calotropis gigantea

Molecules, 2008
A new pregnanone, named calotropone (1), was isolated from the EtOH extract of the roots of Calotropis gigantea L. together with a known cardiac glycoside. The structures were elucidated by a study of their physical and spectral data.
Mao-Yuan Wang, Zhu-Nian Wang, Wen-Li Mei, Zhuang Han, Hao-Fu Dai   +4 more
doaj   +1 more source

Zhenyuan Solid Drink Ameliorates Inflammation and Oxidative Stress in Isoproterenol‐Induced Ischemic Myocardial Infarction via TLR4/NF‐κB Pathway and PI3K/AKT1/NRF2 Pathway in Rats

Food Science &Nutrition, Volume 14, Issue 4, April 2026.
ZYSD exerts curative and preventive cardioprotection against isoproterenol‐induced myocardial infarction through synergistic interaction with probiotics, exerting antioxidant and anti‐inflammatory effects. ABSTRACT Zhenyuan Solid Drink (ZYSD) is a formulation consisting of 6 medicinal herbs that can be used as both food and medicinal materials in China.
Jiawen Huang, Tian Yu, Guoyi Li, Kechao Nie, Donghua Liu, Cong Meng, Xiaoling Shen, Linchun Fu, Liang Long, Zhuotao Fu, Zhitong Deng, Yingjie Hu   +11 more
wiley   +1 more source

The Composition and Biochemical Properties of Strophantus (Apocynaceae), with a Focus on S. sarmentosus

Molecules
The genus Strophantus belongs to the Apocynaceae family of flowering plants which grows primarily in tropical Africa. The plants are widely used in traditional herbal medicine. S. sarmentosus, in particular, is used for the treatment of, e.g., joint pain
Simone König
doaj   +1 more source

Characterisation of Na/K-ATPase, its isoforms, and the inotropic response to ouabain in isolated failing human hearts [PDF]

, 2017
Objective: The aim was to determine whether failing human hearts have increased sensitivity to the inotropic and toxic effects of ouabain, and to examine alterations in Na/K-ATPase that might explain the observed higher ouabain sensitivity.
Gradoux, Nathalie, Grupp, Gunther, Grupp, Ingrid L., Kremers, Walter, Lingrel, Jerry B., Melvin, David, Pover, Alain De, Shamraj, Olga I.   +7 more
core  

The characteristics and prognostic factors on initial presentation to healthcare facilities associated with poor outcomes in acute or acute‐on‐chronic digoxin poisoning in Hong Kong

Hong Kong Journal of Emergency Medicine, Volume 33, Issue 2, April 2026.
Abstract Background Digoxin is a commonly used cardiovascular drug but has a narrow therapeutic window, and its poisoning could be fatal. Prognostic factors of digoxin poisoning were proposed largely based on the toxicokinetics of digoxin. Higher levels of evidence on this topic were limited.
Pui Hang Belle Lau, Yuet Yee Wu, Shing Kit Tommy Lam, Tin Yat Anthony Chow, Ping Wu, Oi Fung Wong, Chi Keung Chan, Man Li Tse   +7 more
wiley   +1 more source

Probing the interaction of lysozyme with cardiac glycoside digitoxin: experimental and in silico analyses. [PDF]

Front Mol Biosci, 2023
Ali MS, Al-Lohedan HA, Bhati R, Muthukumaran J.   +3 more
europepmc   +1 more source

Systematic Druggable Genome‐Wide Analysis Identifies Therapeutic Targets for Aging: A Mendelian Randomization Study

Health Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims Currently, there are no effective drug treatments for aging. Mendelian randomization (MR) has been widely applied to repurpose existing drugs and identify new therapeutic targets. Our aim is to identify aging‐related therapeutic targets and evaluate their potential adverse effects, underlying mechanisms, and actionable ...
Yanfang Zhang, Menglong Wang, Hang Li, Ting Jin, Shanshan Peng, Yi Dong, Chaowei Deng, Hang Li, Xinyi Li, Juanjuan Qin, Xujun Ye   +10 more
wiley   +1 more source

Hepatoprotective Potential and Histological Studies of Effects of Celosia Argentea L. on Paracetamol-Induced Liver Damage [PDF]

, 2018
Celosia argentea L. is a common vegetable known to possess anti-oxidative and other therapeutic properties. This study evaluates the hepatoprotective activities and histological effects of aqueous extract of Celosia argentea L.
Bello, Oluwakemi A., Dokunmu, Titilope M., Ezekiel, O. M., Ogunlana, Olubanke Olujoke, Oladele, F. W., Oyelade, I. F.   +5 more
core  

Biogenic Synthesis of Silver and Iron Nanoparticles Derived From Grewia Optiva Leaf Extract: A Novel Approach for Antidiabetic, Anticoagulant and Anti‐Inflammatory Therapies

International Journal of Chemical Kinetics, Volume 58, Issue 4, Page 159-174, April 2026.
ABSTRACT This study presents the green synthesis of silver (Ag‐NPs) and iron nanoparticles (Fe‐NPs) using aqueous leaf extract of Grewia optiva as a natural reducing and stabilizing agent. The extract was prepared using a Kjeldahl apparatus under controlled heating. Nanoparticle synthesis was optimized by varying pH, temperature, and salt concentration,
Muhammad Salman Khan, Khushbakht Asad, Sehrish Asad, Aulia Kanwal, Abdur Rahim, Mina Ziarati, Muhammad Bilal, Nolubabalo Matinise, Farhad Badshah   +8 more
wiley   +1 more source

Phytosynthesized Silver Nanoparticles from Waste Kigelia africana Flowers: Characterization and Functional Applications

ChemistryOpen, Volume 15, Issue 4, April 2026.
Green synthesized silver nanoparticles from Kigelia africana flower waste were characterized using Ultraviolet–Visible Spectroscopy (UV–Vis), Fourier Transform Infrared Spectroscopy (FT‐IR), Field Emission Scanning Electron Microscopy (FESEM), and X‐ray Diffraction (XRD).
Lakshya, Amanpreet Kaur, Utkarsh Tyagi, Man Vir Singh, Aaysha Pandey, Kamal Kishore, Ranjeet Brajpuria, Soniya Dhiman, Naresh Kumar Wagri   +8 more
wiley   +1 more source