Results 61 to 70 of about 777,596 (195)
The Cardiac Glycosides Present in Mistletoes Growing on Nerium oleander
, 1961 Three species of mistletoe growing on Nerium oleander have been shown to extract selectively cardiac glycosides from the host plant. The substances selected were the three most polar glycosides present in the leaves of N.
SE Wright, C Boonsong
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Senotherapeutics for Knee Osteoarthritis
Medicinal Research Reviews, EarlyView.ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
Enzymatic determination of cardiac glycosides [PDF]
, 1971 A specific and highly sensitive enzymatic method for the determination of cardiac glycosides has been developed. The method is based on the inhibition of the Na,K-ATPase in a microsomal preparation from beef cerebral cortex. The procedure, which involves
Medziharadsky, Fedor +2 more
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Pest Management Science, EarlyView.Plant‐derived nanoemulsion for root‐knot nematode control in tomato: formulation concept, proposed mode of action, and efficacy under pot and greenhouse conditions. Abstract Objective Nanoemulsion‐based delivery systems offer a promising approach to improve the stability and biological performance of plant‐derived nematicides.
Ramanan Ganapathy, Ahmet Aykaç
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Gentiopicroside Regulates EGFR and Induces Its Lysosomal Degradation to Attenuate Heart Failure
Phytotherapy Research, EarlyView.GPS attenuates pressure overload‐induced cardiac remodeling by promoting lysosomal degradation of EGFR. TAC‐induced EGFR accumulation activates AKT/ERK1/2 signaling and drives pathological cardiac hypertrophy, fibrosis, apoptosis, oxidative stress, and cardiac dysfunction. GPS promotes lysosome‐dependent EGFR degradation, thereby limiting excessive AKT/
Mingzhen Cao +6 more
wiley +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Use of cardiac glycosides and risk of glioma
, 2016 Cardiac glycosides induce apoptotic effects on glioma cells, but whether cardiac glycosides protect against risk for glioma is unknown. We therefore explored the relation between glycoside use and glioma risk using a large and validated database.
Meier, Christoph R. +13 more
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Cardiac glycosides initiate Apo2L/TRAIL-induced apoptosis in non-small cell lung cancer cells by up-regulation of death receptors 4 and 5 [PDF]
, 2006 Tumor necrosis factor (TNF)-related apoptosis-inducing ligand (Apo2L/TRAIL) belongs to the TNF family known to transduce their death signals via cell membrane receptors.
Frese-Schaper, Manuela +14 more
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Senolytics and exercise: Dual modalities for rejuvenating muscle
The Journal of Physiology, EarlyView.Abstract figure legend The role of senolytics on the heart and skeletal muscle. Senescent cell burden increases with ageing, disuse and disease. The senolytics dasatinib+quercetin (D+Q), navitoclax and fisetin, as well as exercise, eliminate senescent cells, reducing senescent cell burden and their senescence‐associated secretory phenotype (SASP ...
Zeynep Elif Yesilyurt‐Dirican +4 more
wiley +1 more source
, 2009 Due to high prevalence and mortality and the lack of effective therapies, prostate cancer is one of the most crucial health problems in men. Drug resistance aggravates the situation, not only in human prostate cancer but also in other cancers.
CHUEH, SHIH-CHIEH;TENG, CHE-MING +1 more
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