Results 61 to 70 of about 14,654 (172)

Superior Cardiorenal Protection With Tirzepatide Over Dulaglutide in Heart Failure With Preserved Ejection Fraction: A Large‐Scale Propensity Score–Matched Real‐World Analysis

Clinical Cardiology, Volume 49, Issue 8, August 2026.
In this large real‐world propensity‐matched analysis, tirzepatide demonstrated superior reductions in mortality, hospitalizations, and cardiorenal outcomes versus dulaglutide in HFpEF patients, with a favorable safety profile. ABSTRACT Background No direct head‐to‐head trials compare tirzepatide and dulaglutide in heart failure with preserved ejection ...
Ibrahim Khalil, Md. Imran Hossain, Mst. Mahmuda Akter, Ferdous Wahid, Aizaz Anwar Khalid, Sunjida Amin Promi, Md. Abu Sayed, Mohd Turzo Rahman, Pallab Sarker   +8 more
wiley   +1 more source

Possible Deslanoside‐Induced Left Posterior Fascicular Ventricular Tachycardia: A Case Report

Annals of Noninvasive Electrocardiology
Cardiac glycosides, including Deslanoside, are widely used for ventricular rate control in atrial fibrillation (AF). We report a 73‐year‐old man with paroxysmal AF and no structural heart disease who developed left posterior fascicular ventricular ...
Zhang Wenjun, Chen Yao
doaj   +1 more source

Identification of Volatile Odor Compounds in Extracts of Four Types of Herbaceous Plant Spices via GC × GC–O‐TOF MS

eFood, Volume 7, Issue 4, August 2026.
In this study, sensory evaluation, electronic nose, solid‐phase microextraction, and comprehensive two‐dimensional gas chromatography‐olfactometry‐time‐of‐flight mass spectrometry were used to analyze the volatile compounds and key odor‐active components in the extracts of sour horn, alfalfa, chicory, and fenugreek, and a total of 59 odor‐active ...
Suxing Tuo, Qinghui Jia, Shuang Bi, Yixin Dai, Ting Deng, Hongbing Lu, Jiaxiao Cai, Zifeng Li, Cheng Yang, Kejun Zhong, Bo Kong, Ye Liu   +11 more
wiley   +1 more source

Pharmacological Assessment of Calamus guruba Methanolic Extract: Multitarget Effects on Diabetes, Inflammation, Anxiety, and Depression

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
Calamus guruba Buch.‐Ham. (family Arecaceae) is a highly regarded traditional medicinal plant known for its diverse therapeutic benefits. This research aimed to investigate the antidiabetic, anti‐inflammatory, anxiolytic, and antidepressant effects of the methanolic extract of C. guruba (MECG).
Mohi Uddin, Tania Akter Shorna, Khurshida Jahan Suma, Md. Ekramul Haque Ekram, Masud Rana, Md. Jahirul Islam Mamun   +5 more
wiley   +1 more source

Mechanisms of Lycium barbarum Treatment in Sepsis‐Induced Myocardial Injury: A Network Pharmacology and Experimental Validation Study

Food Science &Nutrition, Volume 14, Issue 8, August 2026.
The chemical characterization of the LB extract confirmed the presence of polysaccharides and specific small‐molecule constituents (e.g., rutin, isoquercitrin). Network pharmacology analysis predicted that the bioactive components of LB were able to interact with core targets such as TP53, AKT1, and JUN, and molecular docking simulations suggested ...
Ruxin Liu, Chunxia Ma, Yujiao Tang, Xue Bai, Liting Yang, Yi Hu, Zesu Niu, Weiliang Xue, Ling Zhang, Mengfei Chen   +9 more
wiley   +1 more source

Morroniside Attenuates Doxorubicin‐Induced Cardiotoxicity by Activating the PI3K/AKT/Nrf2/HO‐1 Pathway to Inhibit Ferroptosis and Oxidative Stress

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Mor activates the PI3K/AKT pathway to promote Nrf2 nuclear translocation and HO‐1 expression, enhancing antioxidants, curbing Fe2+‐induced ROS/lipid peroxidation, suppressing ferroptosis, and alleviating Dox‐induced cardiotoxicity. ABSTRACT Cardiotoxicity induced by doxorubicin (Dox) significantly contributes to increased mortality among cancer ...
Zhi‐Hui Lin, Xing‐Yu Lin, Wen‐Jie Lu, Meng‐Qi Wu, Dong‐Yan Song, Rui‐Dong Cheng   +5 more
wiley   +1 more source

Allamanda cathartica leaves do not contain cardioactive glycosides [PDF]

Arquivo Brasileiro de Medicina Veterinária e Zootecnia
Allamanda cathartica, a plant used in traditional medicine for different purposes, has been considered a cardiotoxic plant. However, the alleged cardiac glycoside was not further studied. Thus, the present study aimed to determine whether the leaves of A.
B.P. Santos, G.P.P. Ataíde, C.J.C. Saraiva, M.S. Teixeira, B. Soto-Blanco   +4 more
doaj   +1 more source

Investigation of the Efficacy of Orientin in Streptozotocin‐Induced Type 1 Diabetes Model and Pancreatic Beta‐TC6 Cells

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 8, August 2026.
Orientin, a natural flavonoid, protects against streptozotocin‐induced pancreatic β‐cell damage by suppressing NF‐κB–mediated inflammation, restoring antioxidant defense (SOD, CAT, GSH), and inhibiting apoptotic (Bax/Bcl‐2, Caspase‐3/9) and pyroptotic (Caspase‐1, IL‐1β) cell death pathways in both an in vivo type 1 diabetes mouse model and Beta‐TC6 ...
Bengul Ozdemir Sarikaya, Seyit Ali Bingol   +1 more
wiley   +1 more source

Cardiovascular Diseases and Cancer: Convergent Proteostasis Networks at the Crossroads of Mechanisms and Therapeutic Opportunities

MedComm, Volume 7, Issue 8, August 2026.
The disruption of proteostasis, encompassing the ubiquitin–proteasome system, autophagy, UPR/ER stress, and chaperone function, represents a fundamental mechanism shared by both cancer and cardiovascular diseases. While these pathways frequently facilitate tumor progression, they are crucial for maintaining proteostasis in cardiac tissue. Consequently,
Jacob Eli García Torres, Norbert Frey, Ashraf Yusuf Rangrez   +2 more
wiley   +1 more source

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

Oikos, Volume 2026, Issue 8, August 2026.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining, Cameron M. Hudson, Jernej Bravničar, Antonella Carosi, Gaël P. J. Denys, Philine G. D. Feulner, Žiga Fišer, Hanna Rosinger, Verena Saladin, Linda Zanella, Davor Zanella, Catherine L. Peichel, Blake Matthews   +12 more
wiley   +1 more source