Results 61 to 70 of about 17,469 (205)

NUDT21 Drives T‐Cell Acute Lymphoblastic Leukemia Through Dual Regulation of Alternative Polyadenylation and Transcriptional Activation

open access: yesAdvanced Science, Volume 13, Issue 34, 19 June 2026.
In summary, our study defines a coordinated oncogenic model in which NUDT21 integrates alternative polyadenylation–dependent UBE2D3 stabilization and transcriptional activation to sustain MYC‐driven T‐ALL cell survival, thereby establishing NUDT21 as a central regulatory node and a promising therapeutic target.
Conglian Qiu   +18 more
wiley   +1 more source

Immunological Detection of Cardiac-Glycosides in Plants

open access: yes, 1994
Australian native and introduced plants were examined, using digoxin immunoassays, to detect the presence of cross-reacting cardiac glycosides. These compounds were found in 27 species from 20 genera. The assay technique can also be used on serum samples
Radford, DJ   +9 more
core   +1 more source

Аgrobacterium rhizogenes – опосредованная трансформация и особенности регенерантов Digitalis purpurea L.

open access: yesФактори експериментальної еволюції організмів, 2016
Aim. The influence of Agrobacterium rhizogenes-mediated transformation on morphological and biochemical features of D.purpurea. The goal was achieved through the study of the properties of the transformed cell cultures and regenerated plants.
Л. Г. Лёшина   +2 more
doaj  

Gas Chromatography‐Mass Spectrometry‐Based Phytochemical Profiling and Bioactivity‐Guided Fractionation of Psidium guineense Stem Extracts: In Vitro and In Silico Insights Into Antioxidant, Antidiabetic and Antibacterial Potentials

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
ABSTRACT Psidium guineense (Myrtaceae) is traditionally used for various medicinal purposes, although its stem remains underexplored. This study provides the first integrated phytochemical, pharmacological and computational evaluation of the stem extracts to elucidate their antioxidant, antidiabetic and antibacterial potential.
Md. Jahid Hossain   +3 more
wiley   +1 more source

Cardiac Glycosides Induce Resistance to Tubulin-Dependent Anticancer Drugs in Androgen-Independent Human Prostate Cancer

open access: yes, 2009
Due to high prevalence and mortality and the lack of effective therapies, prostate cancer is one of the most crucial health problems in men. Drug resistance aggravates the situation, not only in human prostate cancer but also in other cancers.
CHUEH, SHIH-CHIEH;TENG, CHE-MING   +1 more
core  

Use of cardiac glycosides and risk of glioma

open access: yes, 2016
Cardiac glycosides induce apoptotic effects on glioma cells, but whether cardiac glycosides protect against risk for glioma is unknown. We therefore explored the relation between glycoside use and glioma risk using a large and validated database.
Meier, Christoph R.   +6 more
core   +1 more source

Infused Tiger Nut and Almond Nut Crunchy Snacks Enhanced the Nutritional Value and Antioxidant Activity in High‐Fat Diet Fed Rat

open access: yesFood Chemistry International, Volume 2, Issue 2, Page 175-185, June 2026.
Crunches were produced from formulations of almond nuts and tiger nuts (AN–TN) for the plausible management of commodity disease of obese condition. The produced AN–TN crunches showed high consumers acceptability, phenolic, and amylopectin contents. In addition, formulated percentages of AN–TN crunches when fed to high‐fat diet (HFD) fed rats led to ...
Olufunke Florence Ajeigbe   +4 more
wiley   +1 more source

The Cardiac Glycosides Present in Mistletoes Growing on Nerium oleander

open access: yes, 1961
Three species of mistletoe growing on Nerium oleander have been shown to extract selectively cardiac glycosides from the host plant. The substances selected were the three most polar glycosides present in the leaves of N.
SE Wright, C Boonsong
core   +1 more source

Determination of cardiac glycosides and total phenols in different generations of Securigera securidaca suspension culture [PDF]

open access: yesResearch Journal of Pharmacognosy, 2016
Background and objectives: The seeds of Securigera securidaca (L.) Deg. & Dorf. (Fabaceae) are used as anti-diabetic remedy in Iranian folk medicine. The aim of the present study was to establish the callus and suspension culture of S.
Z. Tofighi   +3 more
doaj  

A Case Report of Accidental Intoxication following Ingestion of Foxglove Confused with Borage: High Digoxinemia without Major Complications

open access: yesCase Reports in Cardiology, 2019
Foxglove (Digitalis purpurea L.) leaves are frequently confused with borage (Borago officinalis L.), which is traditionally used as a food ingredient. Due to the presence of the cardiac glycosides, mostly digitoxin, foxglove leaves are poisonous to human
Maria Silvia Negroni   +11 more
doaj   +1 more source

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