Results 191 to 200 of about 175,167 (244)

Breast cancer susceptibility gene 2 upregulation alleviated cardiac hypertrophy in angiotensin II-treated mice. [PDF]

Biochem Biophys Rep
Liu K, Gong XX, Li Y, Li MZ, Si C, Zhou L.   +5 more
europepmc   +1 more source

Identification of a Novel De Novo HECW2 Gene Pathogenic Variant in a Fetus With Cardiac Abnormalities

Prenatal Diagnosis, EarlyView.
Kristina Nimchenko, Bettina Bessieres, Gihad E. Chalouhi, Antonia Pop, Vanina Castaigne, Bertrand Stos, Marie‐Paule Beaujard, Diane Roy, Daniela Laux, Tania Attie‐Bitach   +9 more
wiley   +1 more source

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Cardiac hypertrophy

The Southern medical record
openaire   +3 more sources

Regulatory mechanisms of exercise-induced physiological cardiac hypertrophy: progress and prospects. [PDF]

Front Cardiovasc Med
Cheng P, Zhang X, Si Y, Yin Q, Chen L, Ru Q, Chu C, Xiang H, Liao L, Ran H, Zhang Z, Wu Y.   +11 more
europepmc   +1 more source

Prenatal Presentation of ENPP1‐Associated Generalized Arterial Calcification of Infancy at 15 + 1 Weeks: A Fetal Phenotype–Genotype Report

Prenatal Diagnosis, EarlyView.
Ismail Tekesin, Gunter Kerst, Loredana Delle Chiaie, April Dinwiddie, Heinz Gabriel   +4 more
wiley   +1 more source

Circulating Musclin is associated with skeletal muscle function and subclinical cardiac dysfunction in patients with cancer

British Journal of Pharmacology, EarlyView.
Background and Purpose Musclin (osteocrin) is a skeletal muscle‐derived peptide that has been implicated in cardioprotective signalling pathways. Its relevance in cancer patients, who frequently experience muscle wasting and cardiotoxicity, remains unclear. This study aimed to determine whether circulating Musclin levels reflect functional capacity and
Jannek Brauer, Daniel Finke, Sebastian Romann, Norbert Frey, Joerg Heineke, Lorenz H. Lehmann   +5 more
wiley   +1 more source

RMC-6272, a selective third-generation bi-steric mTORC1 inhibitor, improves cardiac function in pressure overload-induced cardiac hypertrophy. [PDF]

J Mol Cell Cardiol Plus
Rogge M, Fischer J, Jakobi T, Loewenthal Z, Gupta P, Jürgensen L, Frey N, Sandmann C, Völkers M.   +8 more
europepmc   +1 more source

Notoginsenoside‐Fa mitigates vascular endothelial permeability via targeting SUGT1 to stabilize NLRP3 in a resting state

British Journal of Pharmacology, EarlyView.
Background and Purpose Notoginsenoside‐Fa (Noto‐Fa) is an emerging active compound derived from notoginseng with promise in treating cardiovascular diseases. The development of cardiovascular diseases is intricately linked to the damage of vascular endothelium and it is widely acknowledged that numerous chronic inflammation pathways, especially the ...
Xiao‐Ying Yu, Da‐Hao Mai, Xing‐Ming Zhong, Li‐Ting Huang, Lan‐Ting Fu, He‐Cai Wang, Ke Wang, Hai‐Yan Li, Qiu‐He Chen, Yang Chen   +9 more
wiley   +1 more source

Type-1 Ryanodine Receptor Plays an Important Role in Cardiac Hypertrophy and Heart Failure by Increasing Type-2 Ryanodine Receptor-Mediated Calcium Release. [PDF]

Int J Mol Sci
Wang YX, Santos EW, Mistretta S, Yuan Y, Singer HA, Sheu SS, Zheng YM.   +6 more
europepmc   +1 more source