Results 41 to 50 of about 6,808 (263)

Mouse models for the study of postnatal cardiac hypertrophy

International Journal of Cardiology: Heart & Vasculature, 2015
The main objective of this study was to create a postnatal model for cardiac hypertrophy (CH), in order to explain the mechanisms that are present in childhood cardiac hypertrophy.
A. Del Olmo-Turrubiarte, A. Calzada-Torres, G. Díaz-Rosas, I. Palma-Lara, R. Sánchez-Urbina, N.A. Balderrábano-Saucedo, H. González-Márquez, P. Garcia-Alonso, A. Contreras-Ramos   +8 more
doaj   +1 more source

UNC-45a promotes myosin folding and stress fiber assembly [PDF]

, 2017
Contractile actomyosin bundles, stress fibers, are crucial for adhesion, morphogenesis, and mechanosensing in nonmuscle cells. However, the mechanisms by which nonmuscle myosin II (NM-II) is recruited to those structures and assembled into functional ...
Aidan M. Fenix, Anderson, Baird, Barral, Barral, Bazzaro, Beach, Berg, Berg, Billington, Bird, Blanchoin, Breiman, Bujalowski, Burgess, Burnette, Burnette, Case, Chadli, Chadli, Chen, Choi, Chow, Clarke, Comyn, Craig, Dylan T. Burnette, Epping, Epstein, Etard, Etard, Fenix, Gaiser, Gazda, Geach, Gibala, Giuseppe Balistreri, Guo, Gustafsson, Henderson, Horvath, Hotulainen, Hu, Iizuka, Jaakko I. Lehtimäki, Jorrisch, Kamentsky, Lam, Landsverk, Lassi Paavolainen, Lee, Lee, Lee, Liu, Liu, Markku Varjosalo, McNeil, Mehta, Melkani, Melkani, Myhre, Nambiar, Ni, Niederman, Odronitz, Paulsen, Pekka Lappalainen, Price, Ran, Raucher, Roux, Sandquist, Schneider, Schulze, Shih, Shutova, Shutova, Skau, Srikakulam, Thoresen, Toi, Tojkander, Tojkander, Tojkander, Tommi M. Kotila, Umemoto, Venolia, Vicente-Manzanares, Vicente-Manzanares, Wei, Wells, Wohlgemuth, Wolfenson, Ye   +93 more
core   +1 more source

Functional Characterization of Cardiac Myosin Isoforms.

The Japanese Journal of Physiology, 1998
In this brief review, we have discussed the functional significance of cardiac myosin isoform redistribution. The development of in vitro motility assay techniques has greatly aided the research in this field. The next important step would be the integration of data at molecular or cellular level to account for the pathophysiology of animal or human ...
S, Sugiura, H, Yamashita
openaire   +3 more sources

Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family. [PDF]

, 1993
A polymerase chain reaction strategy was devised to identify new members of the mammalian myosin I family of actin-based motors. Using cellular RNA from mouse granular neurons and PC12 cells, we have cloned and sequenced three 1.2-kb polymerase chain ...
Greene, LA, Joyce, MP, Sherr, EH
core  

Differential expression of skeletal muscle genes following administration of clenbuterol to exercised horses. [PDF]

, 2016
BackgroundClenbuterol, a beta2-adrenergic receptor agonist, is used therapeutically to treat respiratory conditions in the horse. However, by virtue of its mechanism of action it has been suggested that clenbuterol may also have repartitioning affects in
Chouicha, Nadira, Harrison, Linda M, Kass, Phil H, Knych, Heather K, Steinmetz, Stacy J   +4 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

Advanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa, Lineta Stonkute, Sara Trujillo, Mariana Azevedo Gonzalez Oliva, Francis Burton, Matthew J. Dalby, Oana Dobre, Godfrey Smith, Manuel Salmeron‐Sanchez   +8 more
wiley   +1 more source

Production of monoclonal antibodies against Streptococcus mutans antigens Produção de anticorpos monoclonais contra antígenos de Streptococcus mutans

Brazilian Oral Research, 2006
Several studies have been conducted in the last decades aiming to obtain an anti-caries vaccine, however some studies have demonstrated cross reactivity between Streptococcus mutans surface antigens and the human cardiac tissue.
Antonio Carlos Victor Canettieri, Fujiko Yamasiro Kretchetoff, Cristiane Yumi Koga-Ito, Daniella Moreira, Fabio José Condino Fujarra, Carmelinda Schmidt Unterkircher   +5 more
doaj   +1 more source

Nonmuscle myosin-2: mix and match [PDF]

, 2012
Members of the nonmuscle myosin-2 (NM-2) family of actin-based molecular motors catalyze the conversion of chemical energy into directed movement and force thereby acting as central regulatory components of the eukaryotic cytoskeleton.
Dietmar J. Manstein, Sarah M. Heissler
core   +1 more source

Cardiac Myosin Light Chain Kinase [PDF]

Circulation Research, 2008
See related article, pages 571–580 Muscle myosin, which is the highly conserved molecular motor, contains 1 pair of myosin heavy chains (MHCs) and 2 pairs of myosin light chains (MLCs), the latter of which are referred to as essential and regulatory light chains.1,2 It is well known that muscle myosin is regulated through the phosphorylation of ...
Yoshihiro Ishikawa, Reiko Kurotani
openaire   +1 more source