Results 31 to 40 of about 4,202 (274)

Multiple myosin motors interact with sodium/potassium-ATPase alpha 1 subunits

open access: yesMolecular Brain, 2018
The alpha1 (α1) subunit of the sodium/potassium ATPase (i.e., Na+/K+-ATPase α1), the prototypical sodium pump, is expressed in each eukaryotic cell. They pump out three sodium ions in exchange for two extracellular potassium ions to establish a cellular ...
Bhagirathi Dash   +2 more
doaj   +1 more source

Supplementary data: Single Cardiac Ventricular Myosins are Autonomous Motors

open access: yes, 2017
The files in this record contain partial data for the paper ‘Single Cardiac Ventricular Myosins are Autonomous Motors’. It includes one movie for unloaded Qdot data of WT, A57G and E143K, one movie for data at 3ug/ml of alpha-actinin, and related ...
Yuan, Chen-Ching (5316586)   +9 more
core   +1 more source

Comparative study of binding pocket structure and dynamics in cardiac and skeletal myosin

open access: yes, 2023
The development of small molecule myosin modulators has seen an increased effort in recent years due to their possible use in the treatment of cardiac and skeletal myopathies.
Antonovic, Anna Katarina   +2 more
core   +1 more source

Heterogeneity of alpha-cardiac myosin heavy chains in a small marsupial, Antechinus flavipes, and the effect of hypothyroidism on its ventricular myosins

open access: yes, 2008
The effect of drug-induced hypothyroidism on ventricular myosin gene expression was explored in a small marsupial, Antechinus flavipes. Pyrophosphate gel electrophoresis, SDS-PAGE and western blotting were used to analyse changes in native myosin ...
Zhong, Wendy W. H.   +2 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach   +23 more
wiley   +1 more source

Mechanical and Electrical Phenotype of hiPSC‐Cardiomyocytes on Fibronectin‐Based Hydrogels

open access: yesAdvanced Healthcare Materials, EarlyView.
We introduce fibronectin‐based PEG hydrogels with controlled rigidity to enable the culture of iPSC‐derived cardiomyocytes. These substrates offer an alternative to the current culture of these cells on fibronectin‐coated glass, providing enhanced structural and functional behavior. The system provides a more physiologically relevant platform to assess
Ana Da Silva Costa   +8 more
wiley   +1 more source

Functional diversity between orthologous myosins with minimal sequence diversity

open access: yes, 2000
To define the structural differences that are responsible for the functional diversity between orthologous sarcomeric myosins, we compared the rat and human beta/slow myosins.
ROSSI, ROSETTA   +5 more
core   +1 more source

Coaxially Electrospun Myocardial dECM‐ Based Nanofibrous Scaffolds Demonstrate Enhanced Cardiomyocyte Biocompatibility

open access: yesAdvanced Healthcare Materials, EarlyView.
Our coaxial electrospinning system is capable of incorporating decellularized myocardial extracellular matrix in a core‐sheath configuration, creating nanofibrous scaffolds. These scaffolds, in turn, support the maintenance of functional cardiomyocytes adhered to the surface of these bioactive scaffolds.
Dhanusha N. Rajapakse   +9 more
wiley   +1 more source

Production of monoclonal antibodies against Streptococcus mutans antigens Produção de anticorpos monoclonais contra antígenos de Streptococcus mutans

open access: yesBrazilian Oral Research, 2006
Several studies have been conducted in the last decades aiming to obtain an anti-caries vaccine, however some studies have demonstrated cross reactivity between Streptococcus mutans surface antigens and the human cardiac tissue.
Antonio Carlos Victor Canettieri   +5 more
doaj   +1 more source

Novel blood coagulation molecules: Skeletal muscle myosin and cardiac myosin

open access: yesJournal of Thrombosis and Haemostasis, 2021
Essentials Striated muscle myosins can promote prothrombin activation by FXa or FVa inactivation by APC. Cardiac myosin and skeletal muscle myosin are pro-hemostatic in murine tail cut bleeding models. Infused cardiac myosin exacerbates myocardial injury caused by myocardial ischemia reperfusion.
Deguchi, Hiroshi   +2 more
openaire   +3 more sources

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