Results 101 to 110 of about 7,413,990 (275)

Cardiac tissue engineering: current state-of-the-art materials, cells and tissue formation

Einstein (São Paulo)
Cardiovascular diseases are the major cause of death worldwide. The heart has limited capacity of regeneration, therefore, transplantation is the only solution in some cases despite presenting many disadvantages.
Isabella Caroline Pereira Rodrigues, Andreas Kaasi, Rubens Maciel Filho, André Luiz Jardini, Laís Pellizzer Gabriel   +4 more
doaj   +1 more source

Mechanoactive Biomaterials for Cell–Matrix Mechanotransduction

Advanced Materials, EarlyView.
The graphical abstract shows how individual triggers (force, light, or temperature) and combined optothermal or receptor‐targeted actuation induce material responses at the tissue, cellular, and receptor scales. Their spatial (global or focused) and temporal (continuous or cyclic) modulation determines the resulting mechanical output.
Yi‐Tung Lu, Alison E. John, Marc A. Fernández‐Yagüe   +2 more
wiley   +1 more source

Biomimetic Polymers for Cardiac Tissue Engineering

Biomacromolecules, 2016
Heart failure is a morbid disorder characterized by progressive cardiomyocyte (CM) dysfunction and death. Interest in cell-based therapies is growing, but sustainability of injected CMs remains a challenge. To mitigate this, we developed an injectable biomimetic Reverse Thermal Gel (RTG) specifically engineered to support long-term CM survival.
Peña, Brisa, Martinelli, Valentina, Jeong, Mark, Bosi, Susanna, Lapasin, Romano, Taylor, Matthew RG, Long, Carlin S, Shandas, Robin, Park, Daewon, Mestroni, Luisa   +9 more
openaire   +4 more sources

Tissue Engineering to Restore Cardiac Function

Engineering, 2022
Richard D. Weisel
doaj   +1 more source

Life‐Like Ferrous Oxide Microspheres from Kombucha

Advanced Materials Interfaces, EarlyView.
Kombucha bacterial cellulose, sodium alginate, and ferrous nitrate self‐assemble into membrane‐enclosed iron oxide microspheres. These microspheres bud daughter vesicles, sustain 24‐h electrochemical oscillations, and filter theta‐band signals.
Panagiotis Mougkogiannis, Anna Nikolaidou, Andrew Adamatzky   +2 more
wiley   +1 more source

Recent Advances in Bioprinting Technologies for Engineering Cardiac Tissue

, 2021
Annually increasing incidences of cardiac-related disorders and cardiac tissue’s minimal regenerative capacity have motivated the researchers to explore effective therapeutic strategies.
Cui, Haitao, Hann, Sung Yun, Di Natale, Concetta, Agarwal, Tarun, Onesto, Valentina, Fortunato, Gabriele Maria, Chan, Alex H. P., Zhang, Lijie Grace, Presutti, Dario, Chan, Alex H-P, Costantini, Marco, Ayan, Bugra, Vajanthri, Kiran Yellappa, Shabani, Majid, Makvandi, Pooyan, Maiti, Tapas Kumar, De Maria, Carmelo, Huang, Ngan F., Vajanthri K. Y., Di Natale C., Fortunato G. M., Shabani M., De Maria C., Agarwal T., Costantini M., Onesto V., Zhang L. G., Ayan B., Chan A. H. P., Maiti T. K., Makvandi P., Hann S. Y., Presutti D., Cui H., Huang N. F., Concetta Di Natale, Tapas Kumar Maiti, Sung Yun Hann, Marco Costantini, Gabriele Maria Fortunato, Pooyan Makvandi, Bugra Ayan, Valentina Onesto, Tarun Agarwal, Carmelo De Maria, Ngan F. Huang, Haitao Cui, Lijie Grace Zhang, Dario Presutti, Alex H.P. Chan, Kiran Yellappa Vajanthri, Majid Shabani   +51 more
core   +1 more source

Reduced Graphene Oxide Enhances the Vascular Organization and Contractile Performance of Fibrin‐Gelatin‐Based Engineered Cardiac Tissue

Advanced Materials Interfaces, EarlyView.
Fibrin–gelatin hydrogels functionalized with reduced graphene oxide create a mechanically stable and bioactive 3D environment for engineered cardiac tissue. The composite matrix promotes endothelial lumen formation, enhances sarcomeric protein expression, and increases contractile performance of embedded cardiomyocytes.
Christoph Kuckelkorn, Marie Baiker, Yajuan Jiang, Ebru Aksoy, Kurt Pfannkuche, Horst Fischer   +5 more
wiley   +1 more source

Manufacturing a Biomimetic Biorecator in Cardiac Tissue Engineering

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2021
Introduction: The direct approach of cardiac tissue engineering is to mimic the natural tissue of heart, considering the significant role of scaffolding and mechanical simulation.
Zahra Shams, Babak Akbari, Sarah Rajabi, Nasser Aghdami   +3 more
doaj  

A Critical Review on the Evolution of Chitosan‐Based Injectable Hydrogels in Bone Regeneration

Advanced Materials Interfaces, EarlyView.
The graphical illustration depicts hydrogel formulation using chitosan and biocompatible cross‐linkers, major advantages, and incorporation of cells, osteoinductive factors, and therapeutic drugs. Following injection, pH‐responsive gelation enables controlled drug release, promotes cell recruitment and osteogenic differentiation, enhances extracellular
Shivani Santosh Sakhrani, Abu ul Hassan S. Rana, S. Sudheer Khan   +2 more
wiley   +1 more source

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

Advanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang, Rachel P. White, Yashasvi Tharani, Michael A. Finocchiaro, Leona M. Ripple, Maksymilian Prondzynski, Tania Konry, Vassilios J. Bezzerides   +7 more
wiley   +1 more source