Results 21 to 30 of about 648 (69)

Pulsatile tubular cardiac tissues fabricated by wrapping human iPS cells-derived cardiomyocyte sheets

Regenerative Therapy, 2019
The purpose of this study was to fabricate pulsatile tubular cardiac tissue using cell sheet based-tissue engineering. First, we fabricated human induced pluripotent stem cell (hiPSc)-derived cardiomyocyte sheets and normal human dermal fibroblast (NHDF)
Shinpei Tsuruyama, Katsuhisa Matsuura, Katsuhisa Sakaguchi, Tatsuya Shimizu   +3 more
doaj   +1 more source

Application of conductive hydrogels in cardiac tissue engineering

STEMedicine, 2023
The fatality rate of myocardial infarction ranks first in cardiovascular disease, which is myocardial necrosis caused by persistent ischemia and hypoxia caused by coronary artery occlusion. Myocardial infarction leads to the irreversible loss of a large
Xiaoyi Ren, Ziyun Jiang, Mingliang Tang
doaj   +1 more source

Cardiac tissue engineering: Multiple approaches and potential applications

Frontiers in Bioengineering and Biotechnology, 2022
The overall increase in cardiovascular diseases and, specifically, the ever-rising exposure to cardiotoxic compounds has greatly increased in vivo animal testing; however, mainly due to ethical concerns related to experimental animal models, there is a ...
Ilaria Gisone, Antonella Cecchettini, Antonella Cecchettini, Elisa Ceccherini, Elisa Persiani, Maria Aurora Morales, Federico Vozzi   +6 more
doaj   +1 more source

Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering [PDF]

BioImpacts
Introduction: Biomaterials currently utilized for the regeneration of myocardial tissue seem to associate with certain restrictions, including deficiency of electrical conductivity and sufficient mechanical strength.
Nazanin Amiryaghoubi, Marziyeh Fathi
doaj   +1 more source

Extrinsically Conductive Nanomaterials for Cardiac Tissue Engineering Applications

Micromachines, 2021
Myocardial infarction (MI) is the consequence of coronary artery thrombosis resulting in ischemia and necrosis of the myocardium. As a result, billions of contractile cardiomyocytes are lost with poor innate regeneration capability.
Arsalan Ul Haq, Felicia Carotenuto, Paolo Di Nardo, Roberto Francini, Paolo Prosposito, Francesca Pescosolido, Fabio De Matteis   +6 more
doaj   +1 more source

Carbon based materials in conducting tissue engineering

Materials Research Express
Conducting materials based on carbon have been widely investigated in conducting tissue engineering applications due to their outstanding physical, chemical, thermal, and electric properties in recent years. Carbon based conductive materials can generate
Elif Sancar, Büşra Oktay, Esma Ahlatcıoğlu Özerol   +2 more
doaj   +1 more source

Inducing Endogenous Cardiac Regeneration: Can Biomaterials Connect the Dots?

Frontiers in Bioengineering and Biotechnology, 2020
Heart failure (HF) after myocardial infarction (MI) due to blockage of coronary arteries is a major public health issue. MI results in massive loss of cardiac muscle due to ischemia.
Assaf Bar, Smadar Cohen, Smadar Cohen, Smadar Cohen   +3 more
doaj   +1 more source

Cardiac tissue engineering: state-of-the-art methods and outlook

Journal of Biological Engineering, 2019
The purpose of this review is to assess the state-of-the-art fabrication methods, advances in genome editing, and the use of machine learning to shape the prospective growth in cardiac tissue engineering.
Anh H. Nguyen, Paul Marsh, Lauren Schmiess-Heine, Peter J. Burke, Abraham Lee, Juhyun Lee, Hung Cao   +6 more
doaj   +1 more source

Application of biomaterials in cardiac tissue engineering: Current status and prospects

MedComm – Biomaterials and Applications
Cardiovascular diseases have become one of the leading causes of death and illness worldwide, posing significant challenges to global health. Due to the limited regenerative capacity of the heart, conventional approaches to treating heart diseases have ...
Dongshan Zhang, Rui He, Ying Qu, Chuan He, Bingyang Chu   +4 more
doaj   +1 more source

Electrospun Scaffolds and Induced Pluripotent Stem Cell-Derived Cardiomyocytes for Cardiac Tissue Engineering Applications

Bioengineering, 2020
Tissue engineering (TE) combines cells, scaffolds, and growth factors to assemble functional tissues for repair or replacement of tissues and organs. Cardiac TE is focused on developing cardiac cells, tissues, and structures—most notably the heart.
Taylor Cook Suh, Alaowei Y. Amanah, Jessica M. Gluck   +2 more
doaj   +1 more source