Results 41 to 50 of about 6,898,187 (235)

Engineering contractile myocardial tissue using extracellular matrix scaffolds [PDF]

, 2013
There is currently an overwhelming need for functional replacement of diseased or damaged cardiac tissue. Biologic based scaffolds are an attractive tissue engineering approach to cardiac repair because they avoid sensitization associated with homograft ...
Remlinger, Nathaniel
core  

Application of conductive hydrogels in cardiac tissue engineering

STEMedicine, 2023
The fatality rate of myocardial infarction ranks first in cardiovascular disease, which is myocardial necrosis caused by persistent ischemia and hypoxia caused by coronary artery occlusion. Myocardial infarction leads to the irreversible loss of a large
Xiaoyi Ren, Ziyun Jiang, Mingliang Tang
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering [PDF]

BioImpacts
Introduction: Biomaterials currently utilized for the regeneration of myocardial tissue seem to associate with certain restrictions, including deficiency of electrical conductivity and sufficient mechanical strength.
Nazanin Amiryaghoubi, Marziyeh Fathi
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Carbon based materials in conducting tissue engineering

Materials Research Express
Conducting materials based on carbon have been widely investigated in conducting tissue engineering applications due to their outstanding physical, chemical, thermal, and electric properties in recent years. Carbon based conductive materials can generate
Elif Sancar, Büşra Oktay, Esma Ahlatcıoğlu Özerol   +2 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Tissue Engineering for Cardiac Regeneration

, 2011
Tissue engineering is an interdisciplinary field that involves engineering, chemistry, biology and medicine and is emerging in the last decade as a possible approach to regenerate an injured organ by using cells, matrix, biological active molecules and ...
Gaetani R., Doevendans P. A. F., Messina E., Sluijter J. P. G.   +3 more
core   +1 more source

Inducing Endogenous Cardiac Regeneration: Can Biomaterials Connect the Dots?

Frontiers in Bioengineering and Biotechnology, 2020
Heart failure (HF) after myocardial infarction (MI) due to blockage of coronary arteries is a major public health issue. MI results in massive loss of cardiac muscle due to ischemia.
Assaf Bar, Smadar Cohen, Smadar Cohen, Smadar Cohen   +3 more
doaj   +1 more source