Results 51 to 60 of about 7,413,990 (275)
Impact of tissue microstructure on a model of cardiac electromechanics based on MRI data [PDF]
, 2011 Cardiac motion is a vital process as it sustains the pumping of blood in the body. For this reason motion abnormalities are often associated with severe cardiac pathologies.
Kevin Burrage +3 more
core +1 more source
Tissue Engineering for Cardiac Regeneration
, 2011 Tissue engineering is an interdisciplinary field that involves engineering, chemistry, biology and medicine and is emerging in the last decade as a possible approach to regenerate an injured organ by using cells, matrix, biological active molecules and ...
Gaetani R. +7 more
core +1 more source
Cardiac Tissue Engineering: A Clinical Perspective
Future Cardiology, 2007 Engineered myocardium may be used to repair myocardial defects. Although not clinically applicable yet, initial studies in rodents have demonstrated the feasibility of tissue engineering based myocardial repair in vivo. In order for restorative treatment to evolve into a functional treatment modality, tissue engineers have to generate human myocardium ...
Zimmermann, Wolfram-Hubertus +2 more
openaire +3 more sources
Application of conductive hydrogels in cardiac tissue engineering
STEMedicine, 2023 The fatality rate of myocardial infarction ranks first in cardiovascular disease, which is myocardial necrosis caused by persistent ischemia and hypoxia caused by coronary artery occlusion. Myocardial infarction leads to the irreversible loss of a large
Xiaoyi Ren, Ziyun Jiang, Mingliang Tang
doaj +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Engineering contractile myocardial tissue using extracellular matrix scaffolds [PDF]
, 2013 There is currently an overwhelming need for functional replacement of diseased or damaged cardiac tissue. Biologic based scaffolds are an attractive tissue engineering approach to cardiac repair because they avoid sensitization associated with homograft ...
Remlinger, Nathaniel
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
FEBS Letters, EarlyView.Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Bioscaffolds of graphene based-polymeric hybrid materials for myocardial tissue engineering [PDF]
BioImpactsIntroduction: Biomaterials currently utilized for the regeneration of myocardial tissue seem to associate with certain restrictions, including deficiency of electrical conductivity and sufficient mechanical strength.
Nazanin Amiryaghoubi, Marziyeh Fathi
doaj +1 more source
Extrinsically Conductive Nanomaterials for Cardiac Tissue Engineering Applications
Micromachines, 2021 Myocardial infarction (MI) is the consequence of coronary artery thrombosis resulting in ischemia and necrosis of the myocardium. As a result, billions of contractile cardiomyocytes are lost with poor innate regeneration capability.
Arsalan Ul Haq +6 more
doaj +1 more source