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Cardiac Tissue Engineering [PDF]
Circulation Research, 2014 The engineering of 3-dimensional (3D) heart muscles has undergone exciting progress for the past decade. Profound advances in human stem cell biology and technology, tissue engineering and material sciences, as well as prevascularization and in vitro assay technologies make the first clinical application of engineered cardiac tissues a realistic option
Marc N, Hirt +2 more
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Electrospun Acellular Heart ECM for Cardiac Tissue Engineering [PDF]
Iranian Journal of Chemical Engineering, 2021 Electrospun nanofiber is one of the promising alternatives for use in tissue engineering and drug delivery due to its controllable characteristics. However, choosing an appropriate biomaterial for a specific tissue regeneration plays a significant role ...
Sh. mashayekhiyan +5 more
doaj +1 more source
Recapitulating Cardiac Structure and Function In Vitro from Simple to Complex Engineering
Micromachines, 2021 Cardiac tissue engineering aims to generate in vivo-like functional tissue for the study of cardiac development, homeostasis, and regeneration.
Ana Rita M. P. Santos +4 more
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Engineered cardiac tissues [PDF]
Current Opinion in Biotechnology, 2011 Cardiac tissue engineering offers the promise of creating functional tissue replacements for use in the failing heart or for in vitro drug screening. The last decade has seen a great deal of progress in this field with new advances in interdisciplinary areas such as developmental biology, genetic engineering, biomaterials, polymer science, bioreactor ...
Rohin K, Iyer +3 more
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Cardiac Tissue Engineering [PDF]
Journal of Cardiovascular Nursing, 2009 The first 2 reviews in this series have described the defining properties of stem cells, their possible sources, and some initial attempts at their clinical use for tissue regeneration and repair. This third and final article in the series describes bioengineering methods for building physical structures to contain and organize implanted cells.
Matthew W, Curtis, Brenda, Russell
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Engineering virtual cardiac tissue [PDF]
Briefings in Bioinformatics, 2001 The kinetics of proteins involved in ion transfer, sequestration and binding in cardiac cells can be modelled to construct a model of the electrical activity of isolated cardiac cells as a system of ordinary differential equations. These cell models may be incorporated into tissue models, which, when combined with histology and anatomy, form virtual ...
Boyett, M. R., Holden, A. V., Zhang, H.
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Cardiac Organoids to Model and Heal Heart Failure and Cardiomyopathies
Biomedicines, 2021 Cardiac tissue engineering aims at creating contractile structures that can optimally reproduce the features of human cardiac tissue. These constructs are becoming valuable tools to model some of the cardiac functions, to set preclinical platforms for ...
Magali Seguret +3 more
doaj +1 more source
Challenges in Cardiac Tissue Engineering [PDF]
Tissue Engineering Part B: Reviews, 2010 Cardiac tissue engineering aims to create functional tissue constructs that can reestablish the structure and function of injured myocardium. Engineered constructs can also serve as high-fidelity models for studies of cardiac development and disease. In a general case, the biological potential of the cell-the actual "tissue engineer"-is mobilized by ...
Gordana, Vunjak-Novakovic +6 more
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Functional Cardiac Tissue Engineering [PDF]
Regenerative Medicine, 2012 Heart attack remains the leading cause of death in both men and women worldwide. Stem cell-based therapies, including the use of engineered cardiac tissues, have the potential to treat the massive cell loss and pathological remodeling resulting from heart attack.
Brian, Liau +2 more
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Transplant Immunology, 2002 Recent progress in implantations of differentiated cardiac and non-cardiac cells as well as adult stem cells into the heart suggests that the irreversible loss of viable cardiac myocytes that occurs during myocardial infarction can be at least partly substituted.
Eschenhagen, Thomas +4 more
openaire +5 more sources