Results 101 to 110 of about 57,535 (289)

Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients

open access: yesItalian Journal of Medicine
Cardiolipin, a critical phospholipid involved in mitochondrial function, has a potential role in the pathogenesis of type 2 diabetes mellitus.
Ayesha Aslam   +7 more
doaj   +1 more source

Isolation and purification of cardiolipin from beef heart.

open access: yesJournal of Lipid Research, 1985
A simple and efficient procedure is described for the preparation of cardiolipin sodium salt from beef heart. A crude phospholipid fraction is isolated by chloroform-methanol extraction of the homogenized tissue, followed by acetone precipitation and ...
E B Smaal   +4 more
doaj   +1 more source

Bioengineered Bacterial Vesicles and Biomimetic Hybrids Eliminate Biofilms and Balance the Gut Microbiome

open access: yesSmall, EarlyView.
Biomimetic nanocarriers based on liposomes and Myxobacteria outer‐membrane vesicles (OMVs) are effective antibiotic delivery systems. Hybrids have a higher drug loading and can target intracellular pathogens, while OMVs evade immune clearance. Biomimetic nanoantibiotics effectively eliminate the biofilms of Gram‐negative bacteria. Besides, Myxobacteria
Leila Pourtalebi Jahromi   +13 more
wiley   +1 more source

Investigating the protective role of the natural hormone Melatonin, in reducing drug-induced cardiotoxicity in the therapy of chronic diseases [PDF]

open access: yes, 2019
Heart failure (HF) is a highly complex disorder and a major end-point of cardiovascular diseases (CVD). The pathogenesis of HF is mostly unresolved but involves interplay between cardiac structural and electrical remodelling, metabolic alterations, cell ...
Kasi Ganeshan, T., Kasi Ganeshan, T.
core  

Complementary transcriptomic, lipidomic, and targeted functional genetic analyses in cultured Drosophila cells highlight the role of glycerophospholipid metabolism in Flock House virus RNA replication [PDF]

open access: yes, 2010
Background Cellular membranes are crucial host components utilized by positive-strand RNA viruses for replication of their genomes. Published studies have suggested that the synthesis and distribution of membrane lipids are particularly important for the
Castorena, Kathryn M   +2 more
core   +4 more sources

ChitoSilkBioPatch: A bio‐inspired wound dressing scaffold for antibiotic‐free diabetic wound management

open access: yesVIEW, EarlyView.
We present ChitoSilkBioPatch, a maleimide‐functionalized chitosan/dACM hydrogel integrated with a stretchable nanopatterned silk mesh to provide intrinsic, antibiotic‐free antibacterial activity and bioactive wound support. The scaffold eliminates S. aureus and P.
Dorsa Dehghan‐Baniani   +12 more
wiley   +1 more source

Docosahexaenoic acid accumulates in cardiolipin and enhances HT-29 cell oxidant production

open access: yesJournal of Lipid Research, 1998
The objective of this study was to investigate membrane fatty acids for their effects on mitochondrial function in live cells. Mitochondrial potential and oxidant production were measured in human colonic adenocarcinoma (HT-29) cells with membranes ...
Steven M. Watkins   +2 more
doaj   +1 more source

The alkaline transition of cytochrome c revisited: Effects of electrostatic interactions and tyrosine nitration on the reaction dynamics [PDF]

open access: yes, 2019
Here we investigated the effect of electrostatic interactions and of protein tyrosine nitration of mammalian cytochrome c on the dynamics of the so-called alkaline transition, a pH- and redox-triggered conformational change that implies replacement of ...
Castro, Maria Ana   +7 more
core   +1 more source

Clinical and pathogenetic value of immune disruptions in manifestation of mixed cryoglobulinemia in patients with chronic hepatitis C

open access: yesZaporožskij Medicinskij Žurnal, 2018
Objective – to discover role of immune disorders in clinical manifestations formation of mixed cryoglobulinemia in patients with CHC. Material and methods. 214 patients with CHC were included in the study.
O. O. Furyk   +2 more
doaj   +1 more source

Sensing of cardiolipin exposure on plasma membranes of apoptotic cells by EryA‐mCherry protein

open access: yesThe FEBS Journal, EarlyView.
An aegerolysin protein erylysin A (EryA) fused with mCherry binds to artificial lipid vesicles supplemented with cardiolipin (CL). This binding is much more specific than that of annexin V, which binds various negatively charged glycerophospholipids (PG, PS, PI). In mammalian cells, the CL exposition at the membrane surface represents an early hallmark
Luka Žeželj   +12 more
wiley   +1 more source

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