Results 121 to 130 of about 66,906 (291)

Correlation of serum cardiolipin levels with physical activity in type 2 diabetes mellitus patients

Italian Journal of Medicine
Cardiolipin, a critical phospholipid involved in mitochondrial function, has a potential role in the pathogenesis of type 2 diabetes mellitus.
Ayesha Aslam, Shazia Bokhari, Riffat Mehboob, Uzma Rafi, Zeeshan Mehboob, Deema Sabtan, Mohammed M. Karami, Hani Sadaka Shalabi   +7 more
doaj   +1 more source

Diminished exercise capacity and mitochondrial bc1 complex deficiency in tafazzin-knockdown mice.

Frontiers in Physiology, 2013
The phospholipid, cardiolipin, is essential for maintaining mitochondrial structure and optimal function. Cardiolipin-deficiency in humans, Barth syndrome, is characterized by exercise intolerance, dilated cardiomyopathy, neutropenia and 3-methyl ...
Corey ePowers, Yan eHuang, Arnold W Strauss, Zaza eKhuchua   +3 more
doaj   +1 more source

Toward understanding the catalytic mechanism for two classes of bacterial phospholipid N‐methyltransferases

The FEBS Journal, EarlyView.
Phospholipid N‐methyltransferases (Pmts) synthesize phosphatidylcholine in many bacteria. In this study, we compared the catalytic mechanisms of two bacterial Pmt classes: the Rhodobacter (R‐) and the Sinorhizobium (S‐) type. Representative enzymes for each class were derived from Rubellimicrobium thermophilum and Agrobacterium tumefaciens ...
Irina Shevyreva, Lena Sophie Fritsch, Leander Mika Koch, Anton Effing, Meriyem Aktas, Franz Narberhaus   +5 more
wiley   +1 more source

Isolation and purification of cardiolipin from beef heart.

Journal of Lipid Research, 1985
A simple and efficient procedure is described for the preparation of cardiolipin sodium salt from beef heart. A crude phospholipid fraction is isolated by chloroform-methanol extraction of the homogenized tissue, followed by acetone precipitation and ...
E B Smaal, D Romijn, W S Geurts van Kessel, B de Kruijff, J de Gier   +4 more
doaj   +1 more source

Mitochondrial fusion and Bid-mediated mitochondrial apoptosis are perturbed by alcohol with distinct dependence on its metabolism [PDF]

, 2018
Environmental stressors like ethanol (EtOH) commonly target mitochondria to influence the cell’s fate. Recent literature supports that chronic EtOH exposure suppresses mitochondrial dynamics, central to quality control, and sensitizes mitochondrial ...
Hajnóczky, György, Madesh, Muniswamy, Naghdi, Shamim, Rubin, Emanual, Slovinsky, William S.   +4 more
core   +3 more sources

Investigation into the delivery and evaluation of a unique Avena sativa (Oat) Lipid Extract on skin barrier using LC‒MS/MS, Raman spectroscopy, immunostaining analysis and skin efficacy

International Journal of Cosmetic Science, EarlyView.
Abstract Objectives Oat lipids are rich in ceramides. In this investigation, we analysed the delivery of a specific Oat Lipid Extract derived from Avena sativa, comprising ‘skin identical’ ratios of fatty acids, ceramides and cholesterol/sterol. This investigation is the first reported investigation of oat lipids utilizing Raman spectroscopy for the ...
E. Gombert, C. Dewis
wiley   +1 more source

The dynamic action of SecA during the initiation of protein translocation [PDF]

, 2013
Biotechnology and Biological Sciences Research Council (BBSRC) [a doctoral training grant Ph.D. studentship to S.W. and project grant number BB/I008675/1] and the Wellcome Trust [project grant number 084452]
Alice Robson, Bauer, Blobel, Breyton, Brundage, Cannon, Deville, Ding, Erlandson, Gelis, Gold, Gold, Gouridis, Hizlan, Hunt, Ian Collinson, Kimura, Or, Osborne, Osborne, Park, Plath, Robson, Robson, Sarah Whitehouse, van den Berg, Vicki A. M. Gold, Whitehouse, Woodbury, Zimmer, Zimmer   +30 more
core   +2 more sources

How cardiolipin modulates the dynamics of respiratory complex I

Science Advances, 2019
Cardiolipin induces conformational changes in complex I that modulate the accessibility of the quinone substrate to the enzyme. Cardiolipin modulates the activity of membrane-bound respiratory enzymes that catalyze biological energy transduction.
Alexander Jussupow, Andrea Di Luca, Ville R. I. Kaila   +2 more
semanticscholar   +1 more source

Plant Peptides on the Rise: From Historical Insight to Future Applications

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant peptides constitute a rapidly expanding class of signalling molecules essential to plant physiology, mediating key processes such as development, stress adaptation, and immune responses. This review traces the history of plant peptide research, from the seminal discovery of systemin to the recent identification of non‐canonical peptides (
Shunxi Wang, Jinghua Zhang, Minghui Chen, Bokai Zhang, Huina Zhao, Liuji Wu   +5 more
wiley   +1 more source

Abstract 067 | Special lecture: cardiolipin and mitochondrial quality control in aging

European Journal of Translational Myology
A progressive decline in mitochondrial oxidative phosphorylation (OxPhos) is a fundamental feature of aging and a strong predictor of mobility loss, cognitive decline, and dementia.
Luigi Ferrucci
doaj   +1 more source