Results 101 to 110 of about 5,312 (162)
Septins in the Middle—Makers and Breakers of Membrane Contact Sites
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley +1 more source
ACR3 as a Key Regulator Antimicrobial Lipopeptide Synthesis and Efflux in Bacillus velezensis HN‐1
Lipopeptides are natural antibiotics produced by Bacillus velezensis. Mutation of acr3 led to the complete loss of antimicrobial activity. Following the biological assays for validation, we found ACR3 protein may serve as a master switch of lipopeptides synthesis regulation, and control transmembrane transport of lipopeptides by the ABC pathway ...
Yuying Shen +10 more
wiley +1 more source
Plant Peptides on the Rise: From Historical Insight to Future Applications
ABSTRACT Plant peptides constitute a rapidly expanding class of signalling molecules essential to plant physiology, mediating key processes such as development, stress adaptation, and immune responses. This review traces the history of plant peptide research, from the seminal discovery of systemin to the recent identification of non‐canonical peptides (
Shunxi Wang +5 more
wiley +1 more source
Abstract figure legend Calciprotein particles (CPPs) are small calcium‐ and phosphate‐containing nanoaggregates associated with the development of vascular disease (CVD) in chronic kidney disease (CKD). Previously, we have shown that CPPs induce endothelial cell (EC) dysfunction, possibly contributing to CVD in CKD, but the underlying molecular ...
Lian Feenstra +9 more
wiley +1 more source
Mieap forms membrane-less organelles involved in cardiolipin metabolism
Summary: Biomolecular condensates (BCs) are formed by proteins with intrinsically disordered regions (IDRs) via liquid-liquid phase separation. Mieap/Spata18, a p53-inducible protein, participates in suppression of colorectal tumors by promoting ...
Yasuyuki Nakamura +4 more
core +1 more source
Abstract figure legend Seasonal changes profoundly reshape honey bee mitochondrial metabolism. In winter, bees shift from complex I (CI)‐ to mitochondrial glycerol‐3‐phosphate dehydrogenase (mG3PDH)‐ and complex II (CII)‐linked respiration. Despite lower CI‐linked respiration ATP production is maintained, suggesting increased energetic efficiency in ...
Adèle Léger +5 more
wiley +1 more source
Shape and Size of Giant Unilamellar Phospholipid Vesicles Containing Cardiolipin
The effect of cardiolipin content on the shape and size of giant palmitoyloleylphosphatidylcholine/cardiolipin vesicles was studied. Unilamellar vesicles were prepared in sugar solution by the method of electroformation, from mixtures containing up to 50
Ales ˇ Iglič +4 more
core
Abstract Increases in body mass are associated with the development of metabolic dysfunction‐associated steatotic liver disease (MASLD). Caloric restriction (CR) is the primary non‐pharmacological defense against MASLD; however, poor CR maintenance induces partial body mass regain (PR), leading to MASLD progression.
Eira E. Jardines +5 more
wiley +1 more source

