Results 81 to 90 of about 5,312 (162)
This graphical abstract delineates noncanonical protein secretion systems across eukaryotes and prokaryotes. Eukaryotic UcPS covers four ER–Golgi bypass pathways, enabling rapid leaderless protein export via direct transmembrane translocation or vesicle‐mediated release.
Qiyuan Yang +8 more
wiley +1 more source
Dysregulated Lipid Metabolism in Hepatocellular Carcinoma: Mechanisms and Therapeutic Strategies
Dysregulated lipid metabolism facilitates hepatocellular carcinoma (HCC) development, progression, immunosuppressive tumor microenvironment (TME) formation, and therapeutic resistance. Notably, the patterns of lipid metabolism vary significantly among different types of HCC driven by various etiologies.
Yi Yi +4 more
wiley +1 more source
Sketching microprotein portraits
Abstract The illustrations of intricate molecular machineries inside cells created by David Goodsell continue to inspire the scientific community. Here, we aim to extend his artworks to include microproteins, a newly recognized class of small proteins with less than 100 amino acids, encoded by small open reading frames.
Gabriel Diaz +6 more
wiley +1 more source
The role of cardiolipin in mitochondrial function and apoptosis
The phospholipid cardiolipin is thought to play an important role in mitochondrial physiology and mitochondrial outer membrane permeabilization (MOMP) during apoptosis. However, this remains controversial due to the lack of good cellular models.
Raemy, Etienne
core +1 more source
Abstract Mitochondrial cristae architecture is central for optimal oxidative phosphorylation and a healthy mitochondrial physiology. The intricate architecture of the inner mitochondrial membrane relies on protein complexes that compartmentalize the membrane by imposing membrane curvature, forming membrane contact sites or membrane subdomains ...
Patrick Horten +3 more
wiley +1 more source
Cardiolipin clusters and membrane domain formation induced by mitochondrial proteins.
International audienceWe show in this study that mitochondrial creatine kinase promotes segregation and clustering of cardiolipin in mixed membranes, a phenomenon that has been proposed to occur at contact sites in the mitochondria.
Schlattner, Uwe +4 more
core +1 more source
The symbiotic interaction between Demodex folliculorum and Corynebacterium kroppenstedtii subsp. demodicis. Created by the author based on genomic and functional analyses presented in this work. The tripartite interaction between the human host, the mite Demodex folliculorum, and its endosymbiont Corynebacterium kroppenstedtii subsp. demodicis.
T. Steegmüller +6 more
wiley +1 more source
Cardiolipin content increased in C70 and C72 groups.
HT1080 cells exited cell cycle arrest and harvested at 0, 4, 8, 16 and 22 hr for cardiolipin extraction in triplicates and then subjected for LC-MS analysis. All cardiolipin species in A. C70 and B.
Yuan-Hao Howard Hsu (665876) +4 more
core +1 more source
Oral administration of Lactobacillus paracasei L9 (L9) reshapes the gut microbiota, specifically increasing the abundance of short‐chain fatty acid (SCFA)‐producing bacteria (e.g., Blautia), thereby leading to a significant elevation of serum propionic acid (97% increase) and butyric acid (193% increase).
Ran Bi +10 more
wiley +1 more source

